Devices and methods for transluminal or transthoracic interstitial electrode placement
    106.
    发明授权
    Devices and methods for transluminal or transthoracic interstitial electrode placement 有权
    用于经腔或经胸腔间隙电极放置的装置和方法

    公开(公告)号:US07191015B2

    公开(公告)日:2007-03-13

    申请号:US10411891

    申请日:2003-04-11

    IPC分类号: A61N1/05

    摘要: Methods and devices for implanting pacing electrodes or other apparatus, or for delivering substances, to the heart of other tissues within the body. A guided tissue penetrating catheter is inserted into a body lumen (e.g., blood vessel) or into a body cavity or space (e.g., the pericardial space) and a penetrator is advanced from the catheter to a target location. In some embodiments, a substance or an apparatus (such as an electrode) may be delivered through a lumen in the penetrator. In other embodiments, a guidewire may be advanced through the penetrator, the penetrating catheter may then be removed and an apparatus (e.g., electrode) may then be advanced over that guidewire. Also disclosed are various implantable electrodes and electrode anchoring apparatus.

    摘要翻译: 用于将起搏电极或其他装置植入或用于输送物质的方法和装置到体内其他组织的心脏。 将引导组织穿透导管插入体腔(例如血管)或插入体腔或空间(例如心包空间)中,并且穿透器从导管前进到目标位置。 在一些实施例中,物质或装置(例如电极)可以通过穿透器中的内腔递送。 在其他实施例中,导丝可以穿过穿透器前进,然后可以移除穿透导管,然后可以在该导丝上前进装置(例如电极)。 还公开了各种可植入电极和电极锚定装置。

    Methods for bypassing total or near-total obstructions in arteries or other anatomical conduits
    110.
    发明授权
    Methods for bypassing total or near-total obstructions in arteries or other anatomical conduits 有权
    绕过动脉或其他解剖导管中的全部或接近完全的障碍物的方法

    公开(公告)号:US06709444B1

    公开(公告)日:2004-03-23

    申请号:US09860147

    申请日:2001-05-17

    申请人: Joshua Makower

    发明人: Joshua Makower

    IPC分类号: A61M2500

    摘要: Methods for bypassing total or near-total obstructions in arteries or other anatomical conduits. A guidewire is advanced through the lumen of the artery or anatomical conduit upstream of the obstruction and past the obstruction. In navigating past the obstruction, this guidewire may advance through tissue that is located within the wall of the artery or anatomical conduit and/or through tissue that is located outside of the wall of the artery or anatomical conduit. After this guidewire has been advanced past the obstruction, a penetrating catheter that is equipped with an orientation element is advanced over that guidewire. The orientation element is then used to aim a penetrator back into the lumen of the obstructed artery or conduit, downstream of the obstruction. The penetrator is then advanced into the lumen of the obstructed artery or conduit, downstream of the obstruction, and a final guidewire is advanced through the penetrator and into the lumen of the artery or conduit downstream of the obstruction. The catheter (and the guidewire that was initially used to pass the obstruction) may then be removed, leaving the final guidewire in place. A balloon or other tract enlarging device may be used to dilate or otherwise enlarge the bypass tract through which the final guidewire extends. Also, a covered or uncovered stent may be placed within the tract to facilitate flow from the lumen of the artery or anatomical conduit upstream of the obstruction, through the newly created bypass tract and back into the lumen of the artery or anatomical conduit downstream of the obstruction.

    摘要翻译: 绕过动脉或其他解剖导管中的全部或接近完全的障碍物的方法。 导丝通过阻塞物上游的动脉或解剖导管的内腔前进通过障碍物。 在导航通过障碍物时,该导丝可以通过位于动脉或解剖导管的壁内的组织和/或通过位于动脉或解剖导管的壁外部的组织前进。 在该导丝已经超过障碍物之后,配备有取向元件的穿透导管在该导丝上前进。 然后使用定向元件将穿透器对准阻塞物下游的阻塞动脉或导管的内腔。 然后将穿透器推进到阻塞动脉或导管的内腔中,阻塞下游,并且最终导丝通过穿透器前进并进入阻塞下游的动脉或导管的内腔。 然后可以移除导管(以及最初用于通过障碍物的导丝),留下最终的导丝。 可以使用球囊或其它扩张装置来扩张或以其他方式扩大最终导丝通过其延伸的旁路管。 此外,覆盖或未覆盖的支架可以放置在管道内,以便于从阻塞物上游的动脉或解剖导管的内腔通过新产生的旁路管并且返回到动脉或解剖导管下游的解剖导管 梗阻。