System and method for efficient computation of simulated thermodynamic property and phase equilibrium characteristics using comprehensive local property models
    111.
    发明授权
    System and method for efficient computation of simulated thermodynamic property and phase equilibrium characteristics using comprehensive local property models 有权
    使用综合局部性质模型有效计算模拟热力学性质和相平衡特征的系统和方法

    公开(公告)号:US07676352B1

    公开(公告)日:2010-03-09

    申请号:US11109840

    申请日:2005-04-19

    IPC分类号: G06F9/455

    CPC分类号: G05B17/02 Y10T137/2196

    摘要: A method of estimating a thermophysical property of a fluid using a local model is disclosed herein. The method includes generating, for use within the local model, a series expansion of thermodynamic equations relating to the thermophysical property and one or more derivatives involving the thermophysical property. The method further includes evaluating, based upon a set of specified values of parameters of the fluid, a first order term of the series expansion and a second order term of the series expansion. The values of the first order term and the second order term are then compared. A value of the thermophysical property is then automatically updated when the values of the first order term and the second order term are found to differ by more than a predefined amount.

    摘要翻译: 本文公开了使用局部模型估计流体的热物理性质的方法。 该方法包括在本地模型中使用与热物理性质相关的热力学方程的串联扩展和涉及热物理性质的一种或多种衍生物。 该方法还包括基于流体的参数的一组指定值来评估串联膨胀的一阶项和串联膨胀的二阶项。 然后比较一阶项和二阶项的值。 当发现一阶项和二阶项的值相差大于预定量时,热物理属性的值被自动更新。

    Apoptosis-based evaluation of chemosensitivity in cancer patients
    113.
    发明授权
    Apoptosis-based evaluation of chemosensitivity in cancer patients 有权
    基于细胞凋亡的癌症患者化学敏感性评估

    公开(公告)号:US07674579B2

    公开(公告)日:2010-03-09

    申请号:US10580170

    申请日:2004-11-26

    申请人: Guillermo Mor

    发明人: Guillermo Mor

    IPC分类号: C12Q1/70 G01N33/53

    摘要: Induction of apoptosis in target cells is a key mechanism by which chemotherapy induces cell killing. An in vitro system has been established for determining carboplatin and paclitaxel (Taxol) chemosensitivity of epithelial ovarian cancer cells, where measurements of caspase-3 activation are surrogate markers for activation of chemotherapy-induced programmed cell death. To validate the assay as a predictor of clinical chemotherapy-induced programmed cell death. To validate the assay as a predictor of clinical chemosensitivity in vitro apoptotic response were compared to the clinical response of the patients from whom the tumor cells were isolated. Caspase-3 activation in response to in vitro chemotherapy to both drugs was shown to have an 83% positive predictive value and a 71% negative predictive value. Markers of apoptosis such as caspase-3 activation can be quantitated and utilized to predict the clinical response to chemotherapy.

    摘要翻译: 诱导靶细胞凋亡是化疗诱导细胞杀伤的关键机制。 已经建立了用于测定上皮性卵巢癌细胞的卡铂和紫杉醇(Taxol)化学敏感性的体外系统,其中半胱天冬酶-3活化的测量是激活化疗诱导的程序性细胞死亡的替代标志物。 验证测定作为临床化疗诱导的程序性细胞死亡的预测因子。 将验证作为临床化学敏感性体外凋亡反应的预测因子与其中分离肿瘤细胞的患者的临床反应进行比较。 对两种药物的体外化疗反应的胱天蛋白酶-3激活显示具有83%的阳性预测值和71%的阴性预测值。 细胞凋亡标志物如胱天蛋白酶-3激活可以定量并用于预测化疗的临床反应。

    Method for diagnosing and distinguishing stroke and diagnostic devices for use therein
    115.
    发明授权
    Method for diagnosing and distinguishing stroke and diagnostic devices for use therein 有权
    用于诊断和区分用于其中的卒中和诊断装置的方法

    公开(公告)号:US07655424B2

    公开(公告)日:2010-02-02

    申请号:US10924283

    申请日:2004-08-23

    申请人: George Jackowski

    发明人: George Jackowski

    IPC分类号: G01N33/00 G01N33/543

    CPC分类号: G01N33/6896 G01N2800/2871

    摘要: A method for determining whether a subject has had a stroke and, if so, the type of stroke which includes analyzing the subject's body fluid for at least four selected markers of stroke, namely, myelin basic protein, S100 protein, neuronal specific enolase and a brain endothelial membrane protein such as thrombomodulin or a similar molecule. The data obtained from the analyses provide information as to the type of stroke, the onset of occurrence and the extent of brain damage and allow a physician to determine quickly the type of treatment required by the subject.

    摘要翻译: 一种用于确定受试者是否具有中风的方法,如果是,则包括分析至少四种选择的中风标志物的主体体液的中风类型,即髓磷脂碱性蛋白,S100蛋白,神经元特异性烯醇化酶和 脑内皮细胞膜蛋白如血栓调节蛋白或类似分子。 从分析获得的数据提供关于中风类型,发生发生和脑损伤程度的信息,并允许医生快速确定受试者所需的治疗类型。

    Method and system for creating graphical and interactive representations of input and output data
    116.
    发明授权
    Method and system for creating graphical and interactive representations of input and output data 有权
    用于创建输入和输出数据的图形和交互式表示的方法和系统

    公开(公告)号:US07650576B2

    公开(公告)日:2010-01-19

    申请号:US10153400

    申请日:2002-05-21

    IPC分类号: G06F3/00

    摘要: The invention relates to a method and tool which allows users to create interactive representations of input and output data, and simulate the associated algorithms used to manipulate this data, that are used in spreadsheet applications and other similar software programs. The interactive simulation is visually represented by a customizable set of components which hereinafter will be referred to as a control panel. The control panels can consist of a variety of components which include user interface elements (such as sliders, buttons, and checkboxes), charts and maps. The underlying simulation is generated based on data sources within an application software program file (e.g., spreadsheet data cells) selected by the user during the control panel creation process.

    摘要翻译: 本发明涉及一种方法和工具,其允许用户创建输入和输出数据的交互式表示,并且模拟用于操纵该数据的相关算法,用于电子表格应用程序和其他类似的软件程序。 交互式模拟由可定制的组件集合在视觉上表示,在下文中将被称为控制面板。 控制面板可以由包括用户界面元素(如滑块,按钮和复选框),图表和地图的各种组件组成。 基于在控制面板创建过程期间由用户选择的应用软件程序文件(例如,电子表格数据单元)内的数据源生成底层模拟。

    System and method for defining a policy enabled network
    117.
    发明授权
    System and method for defining a policy enabled network 有权
    用于定义启用策略的网络的系统和方法

    公开(公告)号:US07650396B2

    公开(公告)日:2010-01-19

    申请号:US11763937

    申请日:2007-06-15

    申请人: Glen D. Tindal

    发明人: Glen D. Tindal

    IPC分类号: G06F15/177 G06F15/173

    摘要: A system and method for communicating with network devices without regard to the device type and/or manufacturer is described. In one embodiment, the present invention provides a global graphical user interface (GUI) for communicating with various network devices. The global GUI includes an intuitive interface driven by a template library. For each device type and each device manufacturer, this template library can store both the attribute fields required for device configuration and the format for communicating those attribute fields. When a network administrator wants to communicate with a particular network device, the template associated with that device can be retrieved from the template library. The network administrator can then populate the attribute fields of that template with the appropriate data. This attribute data can be formatted and provided to the network device.

    摘要翻译: 描述了与网络设备通信而不考虑设备类型和/或制造商的系统和方法。 在一个实施例中,本发明提供用于与各种网络设备通信的全局图形用户界面(GUI)。 全局GUI包括由模板库驱动的直观界面。 对于每个设备类型和每个设备制造商,此模板库可以存储设备配置所需的属性字段和用于传递这些属性字段的格式。 当网络管理员想要与特定网络设备进行通信时,可以从模板库检索与该设备相关联的模板。 然后,网络管理员可以使用适当的数据填充该模板的属性字段。 该属性数据可以格式化并提供给网络设备。

    Footwear with rest support
    118.
    发明授权
    Footwear with rest support 失效
    鞋履休息支持

    公开(公告)号:US07644521B2

    公开(公告)日:2010-01-12

    申请号:US11397060

    申请日:2006-04-03

    IPC分类号: A43B13/14

    CPC分类号: A43C15/02 A43B5/145 A43B13/26

    摘要: Footwear includes a sole with a forefoot region, a heel region, and a mid-sole region positioned between the forefoot region and the heel region. A support structure is positioned within the mid-sole region. The support structure is configured to engage an object to facilitate resistance to gravitational pull.

    摘要翻译: 鞋类包括具有前脚区域,脚后跟区域和位于前脚区域和脚后跟区域之间的中部底部区域的鞋底。 支撑结构位于中间鞋底区域内。 支撑结构被配置为接合物体以促进对重力拉力的阻力。

    Apparatus, system, and method for joint processing in graphics processing units
    119.
    发明授权
    Apparatus, system, and method for joint processing in graphics processing units 有权
    图形处理单元联合处理的装置,系统和方法

    公开(公告)号:US07633505B1

    公开(公告)日:2009-12-15

    申请号:US10991540

    申请日:2004-11-17

    申请人: Brian M. Kelleher

    发明人: Brian M. Kelleher

    IPC分类号: G06F15/16 G06F15/80 G06F13/14

    CPC分类号: G06T1/20

    摘要: A multi-chip graphics system includes a master chip and a slave chip coupled by an interlink. The slave chip performs pixel processing in parallel with the master chip, improving the performance of the master chip. In one embodiment, an individual graphics processing unit (GPU) chip includes a normal operational mode, a master mode, and a slave mode to permit an individual GPU chip to be used as individual processor or to be utilized as part of a master/slave pair.

    摘要翻译: 多芯片图形系统包括通过互连耦合的主芯片和从芯片。 从芯片与主芯片并行执行像素处理,提高了主芯片的性能。 在一个实施例中,单个图形处理单元(GPU)芯片包括正常操作模式,主模式和从模式,以允许单个GPU芯片用作单独处理器或用作主/从器件的一部分 对。

    Controlled release potassium chloride tablets
    120.
    发明授权
    Controlled release potassium chloride tablets 失效
    控释氯化钾片

    公开(公告)号:US07632521B2

    公开(公告)日:2009-12-15

    申请号:US10619924

    申请日:2003-07-15

    摘要: A unit dosage form, such as a tablet for delivering potassium into the body in a controlled release fashion, comprises of a multiplicity of microencapsulated potassium chloride crystals, which are further coated with a plasticized polymer to improve compressibility of the microcapsules. The compressible microcapsules are blended with a compression aid, such as microcrystalline cellulose and a glidant, such as colloidal silicon dioxide, to form controlled release potassium chloride tablets. The tablets may optionally include other excipients such as surfactants and disintegrants. The tablets thus produced exhibit not only high crushing strength and low friability but also release potassium in humans in a desired controlled release fashion similar to commercially available potassium chloride tablets.

    摘要翻译: 单位剂型,例如以控制释放方式将钾输送到体内的片剂,包含多个微胶囊化的氯化钾晶体,其进一步用增塑聚合物涂覆以改善微胶囊的压缩性。 可压缩微胶囊与压缩助剂如微晶纤维素和助流剂如胶体二氧化硅混合,形成控制释放的氯化钾片。 片剂可以任选地包括其它赋形剂,例如表面活性剂和崩解剂。 如此生产的片剂不仅具有高的抗碎强度和低脆性,而且以类似于市售的氯化钾片剂的所需的控制释放方式释放人体中的钾。