摘要:
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
摘要:
A computing device, such as a desktop, laptop, tablet computer, a mobile device, or a computing device integrated into another device (e.g., an entertainment device for gaming, a television, an appliance, kiosk, vehicle, tool, etc.) is configured to determine user input commands from the location and/or movement of one or more objects in a space. The object(s) can be imaged using one or more optical sensors and the resulting position data can be interpreted in any number of ways to determine a command. An interactive volume can be defined and adjusted so that the same movement at different locations within the volume may result in different corresponding movement of a cursor or other interpretations of input.
摘要:
A computing device, such as a desktop, laptop, tablet computer, a mobile device, or a computing device integrated into another device (e.g., an entertainment device for gaming, a television, an appliance, kiosk, vehicle, tool, etc.) is configured to determine user input commands from the location and/or movement of one or more objects in a space. The object(s) can be imaged using one or more optical sensors and the resulting position data can be interpreted in any number of ways to determine a command, including 2-dimensional and 3-dimensional movements with or without touch.
摘要:
Compositions comprising extracts or isolated or purified compounds from plants of the genus Corydalis provide prevention and treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, hepatic steatosis, and metabolic syndrome. Corydalis compounds and their derivatives of natural and synthetic origins lower total cholesterol, LDL-cholesterol, and triglycerides and increase hepatic LDL receptor expression and activate AMP-activated protein kinase. Specific stereoisomers of Corydalis compounds with lipid lowering activity include 14R-(+)-corypalmine, 14R,13S-(+)-corydaline, 14R-(+)-tetrahydropalmatin, (+)-corlumidin, d-(+)-bicuculline, and (+)-egenine.
摘要:
A cleaning composition with a limited number of natural ingredients contain a hydrophobic syndetic, a hydrophilic syndetic, and a biguanide or a cationic quaternary ammonium salt. The cleaning composition can be used to clean laundry, soft surfaces, and hard surfaces and cleans as well or better than commercial compositions containing synthetically derived cleaning agents.
摘要:
This application relates to recombinant human interferon-like proteins. In one embodiment a recombinant protein created by gene shuffling technology is described having enhanced anti-viral and anti-proliferative activities in comparison to naturally occurring human interferon alpha 2b (HuIFN-α2b). The invention encompasses a polynucleotide encoding the protein and recombinant vectors and host cells comprising the polynucleotide. Preferably the polynucleotide is selected from the group of polynucleotides each having a sequence at least 93% identical to SEQ ID: No. 1 and the protein is selected from the group of proteins each having an amino acid sequence at least 85% identical to SEQ ID No: 2. The proteins and compositions comprising the proteins can be used for treatment of conditions responsive to interferon therapy, such as viral diseases and cancer.
摘要翻译:本申请涉及重组人类干扰素样蛋白。 在一个实施方案中,与天然存在的人类干扰素α2b(HuIFN-α2b)相比,描述了通过基因改组技术产生的重组蛋白质具有增强的抗病毒和抗增殖活性。 本发明包括编码蛋白质的多核苷酸和包含多核苷酸的重组载体和宿主细胞。 优选地,多核苷酸选自各自具有与SEQ ID:No.1至少93%相同的序列的多核苷酸,并且所述蛋白质选自蛋白质组,其各自具有与SEQ ID NO:至少85%相同的氨基酸序列 否:2.包含蛋白质的蛋白质和组合物可用于治疗对干扰素治疗(例如病毒性疾病和癌症)有反应的病症。
摘要:
The present invention relates to various methods of sensitizing and modifying nanosensor platforms. In one embodiment, the present invention provides a method of increasing sensitivity by inhibiting oxidation of one or more 1,4-hydroquinone (HQ) molecules, functionalizing the nanosensor by using one or more diazonium molecules, creating one or more oxidized carbon groups on the nanosensor, and/or depositing one or more metal clusters on the nanosensor.
摘要:
A method includes defining a placeholder widget having a property and defining a prototype graphical user interface (GUI) having an instance of the placeholder widget. The method also includes presenting the prototype GUI to a user, where an appearance of the instance of the placeholder widget is based on the property of the placeholder widget. The method further includes replacing the instance of the placeholder widget in the prototype GUI with an instance of another widget. In addition, the method includes updating the presentation of the prototype GUI using the instance of the other widget. Replacing the instance of the placeholder widget with the instance of the other widget could include transforming an instance of a lower fidelity placeholder widget into an instance of a higher fidelity widget. The property of the placeholder widget could include a textual property, an image property, and/or a graphics property.
摘要:
The invention features 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs, compositions containing them, and methods of using them as PPAR delta modulators to treat or inhibit the progression of, for example, dyslipidemia.
摘要:
A method and system for enhancing interaction of a virtual keyboard in a small touch screen. The virtual keyboard includes multiple virtual keys and can be divided into more than one block. Proximity sensors associated with the touch screen can sense the 3D position of a physical selector (e.g., user's finger or stylus) before it contacts the touch screen. When the physical selector is close enough to the touch screen, a block of the virtual keyboard or group of characters nearest the physical selector can be enlarged for selection by physical contact of the physical selector with the touch screen. The virtual keyboard can also be enlarged according to the position of the physical selector in a continual manner, wherein the extent of the enlargement is proportional to the proximity of the physical selector to the screen. Further, a character immediately under the physical selector can also be enlarged in order to determine intent with high reliability.