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公开(公告)号：US5599527A
公开(公告)日：1997-02-04
申请号：US340568
申请日：1994-11-14
申请人： Donald P. Hsu , Rajnish Kohli , Michael Prencipe
发明人： Donald P. Hsu , Rajnish Kohli , Michael Prencipe
摘要： A storage stable oral composition which is effective against calculus which contains an orally acceptable vehicle having incorporated therein an effective anticalculus combination of about 0.5 to about 2% by weight of a water soluble pyrophosphate salt and about 0.5 to about 3% by weight of a water soluble polyphosphate salt. The presence in the composition of polyvalent metal compounds and fluoride compounds do not affect the stability of the composition as well as reactive ingredients such as peroxide and bicarbonate compounds.
摘要翻译： 一种储存稳定的口腔用组合物，其对于结石有效，其含有口服可接受的载体，其中加入了约0.5至约2重量％的水溶性焦磷酸盐和约0.5至约3重量％水的有效抗结石组合 可溶性多磷酸盐。 在多价金属化合物和氟化物的组成中的存在不影响组合物的稳定性以及反应性成分如过氧化物和碳酸氢盐化合物。
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132.发明授权Oral compositions containing stabilized stannous compounds having antiplaque and antitartar efficacy 失效含有稳定的亚锡化合物的口服组合物具有抗斑和抗药效
公开(公告)号：US5578293A
公开(公告)日：1996-11-26
申请号：US350309
申请日：1994-12-06
摘要： An aqueous oral care composition containing a stannous ion releasing compound and a combination of a pyrophosphate salt, and an organic acid compound, the combination being present in the composition in an amount sufficient to effectively stabilize the stannous ion concentration.
摘要翻译： 一种含有离子释放化合物的水性口腔护理组合物和焦磷酸盐和有机酸化合物的组合，该组合物以足以有效稳定亚锡离子浓度的量存在于组合物中。
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公开(公告)号：US5487906A
公开(公告)日：1996-01-30
申请号：US356804
申请日：1994-12-15
CPC分类号： A61K33/24
摘要： A method for the preparation of an aqueous stable premix containing a stannous ion releasing compound useful in the manufacture of an aqueous oral care composition containing a stable stannous ion releasing compound which comprises first dissolving the stannous compound in an aqueous solution of critic acid or its alkali metal salt to prepare the aqueous premix to the vehicle of the oral care composition.
摘要翻译： 一种制备含有稳定的亚锡离子释放化合物的水性稳定预混物的方法，其用于制备含有稳定的亚锡离子释放化合物的水性口腔护理组合物，其包括首先将亚锡化合物溶解在批评酸或其碱的水溶液中 金属盐，以将水性预混物制备成口腔护理组合物的载体。
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公开(公告)号：US5453265A
公开(公告)日：1995-09-26
申请号：US181525
申请日：1994-01-13
申请人： Abdul Gaffar , Nuran Nabi , John Afflitto , Drum Stringer , Michael Prencipe
发明人： Abdul Gaffar , Nuran Nabi , John Afflitto , Drum Stringer , Michael Prencipe
CPC分类号： A61K8/24 , A61K8/347 , A61K8/42 , A61K8/8164 , A61Q11/00 , A61K2800/87
摘要： An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2'-hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.
摘要翻译： 含有口服可接受的载体的口服组合物洁齿剂，约30-75重量％的牙齿可接受的水不溶性抛光剂，基本上不溶于水的非阳离子抗菌抗斑剂如2,4,4'-三氯-2' - 羟基 - 二苯基醚（三氯生）抗菌增强剂，其增强了所述抗菌剂向口腔表面和表面活性剂和/或调味油的输送和保留。
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公开(公告)号：US5385729A
公开(公告)日：1995-01-31
申请号：US933851
申请日：1992-08-24
IPC分类号： A61K8/00 , A61K8/21 , A61K8/24 , A61K8/25 , A61K8/29 , A61K8/34 , A61K8/36 , A61K8/40 , A61K8/60 , A61K8/72 , A61K8/73 , A61K8/81 , A61K8/85 , A61K8/97 , A61Q5/06 , A61Q11/00 , A61Q19/00 , A61Q19/10 , A61K7/06 , A61K7/48
CPC分类号： A61K8/042 , A61K8/8135 , A61K8/8164 , A61K8/8182 , A61Q11/00 , A61Q19/00 , A61Q19/10 , A61Q5/06 , A61K2800/48 , A61K2800/52
摘要： A personal care composition in the form of a hair or skin-treating gel containing an amount of a synthetic linearly viscoelastic cross-linked polymeric thickening agent, especially a cross-linked methyl vinyl ether/maleic anhydride copolymer, effective to render the composition linearly viscoelastic, and a method of promoting personal care by applying an effective amount of the composition to the hair or skin.
摘要翻译： 一种以毛发或皮肤处理凝胶形式的个人护理组合物，其含有一定量的合成线性粘弹性交联聚合物增稠剂，特别是交联的甲基乙烯基醚/马来酸酐共聚物，其有效地使组成线性粘弹性 以及通过将有效量的组合物施用于毛发或皮肤来促进个人护理的方法。
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公开(公告)号：US10391038B2
公开(公告)日：2019-08-27
申请号：US12866766
申请日：2009-02-06
摘要： The invention provides a method of treating sensitive teeth comprising attaching a sealant composition comprising a basic amino acid to a person's tooth and allowing the basic amino acid to be slowly released over time in order to reduce chrome and/or acute tooth sensitivity together with compositions and methods of use.
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公开(公告)号：US10098829B2
公开(公告)日：2018-10-16
申请号：US14116371
申请日：2011-06-02
申请人： Steven Fisher , Lynette Zaidel , Michael Prencipe
发明人： Steven Fisher , Lynette Zaidel , Michael Prencipe
摘要： A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients. The composition comprises a source of metal ions, an inorganic phosphate salt having four or more phosphorus atoms and a cross-linked polyvinylpyrrolidone thickening agent in a single phase. Preferred metal ions are stannous, copper and zinc, in particular from zinc citrate and stannous fluoride.
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138.发明授权公开(公告)号：US09968803B2
公开(公告)日：2018-05-15
申请号：US13503801
申请日：2009-10-29
申请人： Linh Fruge , Steven Wade Fisher , Michael Prencipe
发明人： Linh Fruge , Steven Wade Fisher , Michael Prencipe
CPC分类号： A61Q11/00 , A61K8/20 , A61K8/24 , A61K8/365 , A61K2800/31
摘要： A dentifrice composition having a low water phase comprising effective amounts of polyphosphate and ionic active ingredients.
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139.发明授权公开(公告)号：US09937365B2
公开(公告)日：2018-04-10
申请号：US13262010
申请日：2010-04-01
CPC分类号： A61Q11/00 , A61K8/19 , A61K8/20 , A61K8/25 , A61K2800/412
摘要： The invention encompasses combinations of bioactive glass composition and potassium salts that are useful in conjunction with delivery agent such as, for example, toothpastes, mouthwashes, and oral gels. In certain embodiments, the compositions of the invention form a rapid and continuous reaction with body fluids (e.g., saliva) to promote the immediate and long-tem release of Ca and P ions to produce a stable crystalline layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.
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公开(公告)号：US09918918B2
公开(公告)日：2018-03-20
申请号：US12866780
申请日：2009-02-06
摘要： The present invention provides tooth-whitening compositions comprising a bleaching agent and a basic amino acid, together with devices for application thereof, and methods of use therefor.
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