公开(公告)号：US20190258075A1

公开(公告)日：2019-08-22

申请号：US16374849

申请日：2019-04-04

Applicant: KOWA COMPANY, LTD.

Inventor： Hirofumi YAGI

IPC: G02B27/64 ,  H04N5/232 ,  H04N5/225 ,  G03B17/14 ,  G02B7/02 ,  G03B9/02 ,  G03B15/00

Abstract: A lens barrel detachably attached to a camera body includes a fixed tube section that has a base end installed at the camera body, and a top end, a first pitch screw section being formed on an inner peripheral surface of the top end; a movable tube section that is a tube member configured to hold a plurality of lens and has a second pitch screw section on the movable tube side formed at an outer peripheral surface, and is located so as to be movable inside the fixed tube section in such a state that the second pitch screw section is threadedly engaged with the first pitch screw section, the plurality of lens including two group of lenses, a first group and a second group, held within the movable tube section. The movable tube section having a fixed diaphragm plate that is detachable.

公开(公告)号：US10376523B2

公开(公告)日：2019-08-13

申请号：US15514259

申请日：2015-09-25

Applicant: KOWA COMPANY, LTD.

Inventor： Shin Sugimoto

IPC: A61K31/551 ,  A61K47/18 ,  A61K9/08 ,  A61P27/02 ,  A61K9/00 ,  A61K31/435 ,  A61K33/42

Abstract: An aqueous composition having an excellent antiseptic effect is provided. An aqueous composition containing: a compound represented by Formula (1), a salt thereof, or a solvate of the compound or the salt thereof, where X represents a halogen atom, and a quaternary ammonium surfactant. A method for producing an aqueous composition with an antiseptic effect, by incorporating a compound represented by Formula (1), a salt thereof, or a solvate of the compound or the salt thereof and a quaternary ammonium surfactant into the aqueous composition.

公开(公告)号：US20190104698A1

公开(公告)日：2019-04-11

申请号：US16092034

申请日：2017-04-19

Applicant: KOWA COMPANY, LTD.

Inventor： Naoki MIWA ,  Daisuke NITTA

IPC: A01G31/02

Abstract: [Problem] Provided is a compact cultivation device which has a number of management items (parameters) such as air temperature and CO2 concentration in cultivation space.[Solution] A compact cultivation device 1 according to the present invention is provided with; an air conditioning sensor 6 which detects the air temperature, the CO2 concentration, the humidity, or an air current in a cultivation space A; and a nutrient liquid sensor 8 which detects the temperature, the flow rate, the EC, or the pH of a cultivation liquid B. The compact cultivation device 1 is configured to allow cultivation of a plant V while controlling various management items detected by the sensors 6, 8.

公开(公告)号：US10206439B2

公开(公告)日：2019-02-19

申请号：US13522670

申请日：2011-01-24

Applicant: Kazuhiko Matsuo ,  Hidefumi Koga

Inventor： Kazuhiko Matsuo ,  Hidefumi Koga

IPC: A41D13/08 ,  A61F5/01 ,  A61F13/10 ,  A63B71/12

Abstract: An elbow joint supporter includes a first anchor section formed by wrapping one end of a tubular knitted fabric around the wearer's upper arm, a second anchor section formed by wrapping the other end of the fabric around the wearer's forearm, and a substantially X-shaped knitted supporting section intersecting at the wearer's cubital fossa. Two ends of the X-shaped knitted fabric are joined to the first anchor section and the other two ends of the X-shaped knitted fabric are joined to the second anchor section so as to support the wearer's elbow joint. In the circumferential direction of the fabric, the stretch resistances of the first anchor part and the second anchor part are larger than that of a base fabric section. In the length direction of the fabric, the stretch resistance of the supporting section is larger than that of the base fabric section.

公开(公告)号：US20190030005A1

公开(公告)日：2019-01-31

申请号：US16150514

申请日：2018-10-03

Applicant: KOWA COMPANY, LTD.

Inventor： Toshiaki Takizawa

IPC: A61K31/423 ,  A61K31/202 ,  A61K31/232

Abstract: This invention provides a combination-drug composition and a combination use of pharmaceuticals for preventing and/or treating dyslipidemia states, such as hyper-LDL cholesterolemia, in mammals, including humans. This invention pertains to a drug composition for preventing and/or treating dyslipidemia and the like, said drug composition comprising the following: (R)-2-[3-[[N-(benzoxazole-2-yl)-N-3-(4-methoxyphenoxy)propyl] aminomethyl]phenoxy] butyric acid, a salt thereof, or a solvate of either; and an omega-3 fatty acid or an ester derivative of an ω-3 fatty acid.

公开(公告)号：US20180256595A1

公开(公告)日：2018-09-13

申请号：US15755700

申请日：2016-08-31

Applicant: KOWA COMPANY, LTD.

Inventor： Kenji Kawamata ,  Kazushi Maruo ,  Hideki Suganami

IPC: A61K31/551 ,  A61P27/06

CPC classification number: A61K31/551 ,  A61K45/00 ,  A61P27/06

Abstract: The present invention pertains to a drug available for long-term continuous administration for preventing or treating glaucoma or ocular hypertension, said drug showing no decrease in efficacy during long-term administration and exhibiting a stable ocular hypotensive effect. The present invention pertains to a therapeutic agent for glaucoma or ocular hypertension that is to be continuously administered for a long period of time, said drug comprising an Rho kinase inhibitor, more specifically, to a therapeutic agent comprising an Rho kinase inhibitor for treating glaucoma or ocular hypertension in a patient suffering from glaucoma or ocular hypertension who has been administered with a therapeutic agent comprising the Rho kinase inhibitor for treating glaucoma or ocular hypertension continuously over a definite period of time and needs a further enhanced ocular hypotensive effect.

公开(公告)号：US20180250274A1

公开(公告)日：2018-09-06

申请号：US15903279

申请日：2018-02-23

Applicant: KOWA COMPANY, LTD.

Inventor： Mitsumasa NAKAMURA ,  Satoshi KOJIMA ,  Ryohei TANIGAWA

IPC: A61K31/423 ,  A61K31/575 ,  A61P1/16

CPC classification number: A61K31/423 ,  A61K31/575 ,  A61P1/16

Abstract: The present invention relates to a pharmaceutical composition for the treatment of primary biliary cirrhosis (PBC), in which containing a therapeutically effective amount of (R)-2-[3-[[N-(benzoxazol-2-yl)-N-3-(4-methoxyphenoxy)propyl]aminomethyl]phenoxy] butyric acid, a salt thereof, or a solvate thereof.

公开(公告)号：US20180224712A1

公开(公告)日：2018-08-09

申请号：US15504419

申请日：2015-09-07

Applicant: KOWA COMPANY, LTD.

Inventor： Shuichi TOMINAGA ,  Suguru HANZAWA

IPC: G03B9/06 ,  G02B7/02

CPC classification number: G03B9/06 ,  G02B5/005 ,  G02B7/02

Abstract: In the present invention, an edge face of an diaphragm ring (4) has a part (a locked portion) wherein a plurality of depressions (62) are formed and a substantially flat surface wherein no depression (62) is formed, and by a simple operation of operating a link releaser (52) so as to rotate the diaphragm ring (4), it is possible to switch between a click mode and a non-click mode. When taking still images, a diaphragm value can be fixed by using the click mode, and when video is taken, the diaphragm value can be smoothly changed during imaging by using the non-click mode.

公开(公告)号：US20180185337A1

公开(公告)日：2018-07-05

申请号：US15904922

申请日：2018-02-26

Applicant: KOWA COMPANY, LTD.

Inventor： Toshiaki Takizawa ,  Yasunobu Yoshinaka

IPC: A61K31/423 ,  A61K45/06 ,  A61K31/397

CPC classification number: A61K31/423 ,  A61K31/397 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention addresses the problem of providing a pharmaceutical combination composition and drug combinations for the prevention and/or treatment of dyslipidemic conditions such as atherosclerosis, hypercholesterolemia, low HDL blood disease in mammals including humans. A pharmaceutical composition for the prevention and/or treatment of dyslipidemia, etc. which comprises (a) a compound represented by the general formula (1) (in the formula, each symbol is the same as defined in the specification) or a salt thereof or a solvate thereof and (b) a cholesterol absorption inhibitor.

公开(公告)号：US09931321B2

公开(公告)日：2018-04-03

申请号：US15399856

申请日：2017-01-06

Applicant: KOWA COMPANY, LTD.

Inventor： Toshiaki Takizawa ,  Yasunobu Yoshinaka

IPC: A61K31/423 ,  A61K31/397 ,  A61K45/06

CPC classification number: A61K31/423 ,  A61K31/397 ,  A61K45/06 ,  A61K2300/00

Abstract: The present invention addresses the problem of providing a pharmaceutical combination composition and drug combinations for the prevention and/or treatment of dyslipidemic conditions such as atherosclerosis, hypercholesterolemia, low HDL blood disease in mammals including humans. A pharmaceutical composition for the prevention and/or treatment of dyslipidemia, etc. which comprises (a) a compound represented by the general formula (1) (in the formula, each symbol is the same as defined in the specification) or a salt thereof or a solvate thereof and (b) a cholesterol absorption inhibitor (1).