公开(公告)号：US20110191897A1

公开(公告)日：2011-08-04

申请号：US12977211

申请日：2010-12-23

Applicant: Fabien Poree ,  Bernd Laber ,  Nathalie Knittel-Ottleben ,  Gudrun Lange ,  Arno Schulz ,  Ruediger Hain

Inventor： Fabien Poree ,  Bernd Laber ,  Nathalie Knittel-Ottleben ,  Gudrun Lange ,  Arno Schulz ,  Ruediger Hain

IPC: A01H5/00 ,  C07H21/04 ,  C12N15/63 ,  C12N5/10 ,  A01H5/10 ,  C12N15/87 ,  A01N35/06 ,  A01N43/80 ,  A01P13/00 ,  C11B1/10 ,  A01N43/40 ,  A01N37/34 ,  A01N43/56 ,  A01N43/08

CPC classification number: C12N15/8274 ,  C12N9/0069

Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from protists belonging to the family Blepharismidae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

Abstract translation: 本发明涉及编码由属于Blepharismidae家族的原生生物获得的羟基苯基丙酮酸双加氧酶（EC 1.13.11.27，本文缩写为HPPD）以及由此编码的蛋白质的核酸序列，以及包含该核酸的嵌合基因 序列，以及使用这种核酸序列，蛋白质或嵌合基因来获得对HPPD抑制剂除草剂具有耐受性的植物。

公开(公告)号：US08853495B2

公开(公告)日：2014-10-07

申请号：US12977122

申请日：2010-12-23

Applicant: Fabien Poree ,  Bernd Laber ,  Nathalie Knittel-Ottleben ,  Gudrun Lange ,  Arno Schulz ,  Ruediger Hain

Inventor： Fabien Poree ,  Bernd Laber ,  Nathalie Knittel-Ottleben ,  Gudrun Lange ,  Arno Schulz ,  Ruediger Hain

IPC: C12N15/82 ,  C12N9/02

CPC classification number: C12N15/8274 ,  C12N9/0069 ,  C12Y113/11027

Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from Euryarchaeota belonging to the family Picrophilaceae, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

Abstract translation: 本发明涉及从属于皮肤科​​科属的Euryarchaeota获得的编码羟基苯基丙酮酸双加氧酶（EC 1.13.11.27，本文缩写为HPPD）的核酸序列，以及由此编码的蛋白质以及包含该核酸的嵌合基因 序列，以及使用这种核酸序列，蛋白质或嵌合基因来获得对HPPD抑制剂除草剂具有耐受性的植物。

公开(公告)号：US20140024530A1

公开(公告)日：2014-01-23

申请号：US14006049

申请日：2012-03-21

Applicant: Fabien Poree ,  Andreas Almsick ,  Ralf Braun ,  Bernd Laber ,  Ruediger Hain

Inventor： Fabien Poree ,  Andreas Almsick ,  Ralf Braun ,  Bernd Laber ,  Ruediger Hain

IPC: A01N57/24 ,  A01N47/28 ,  A01N43/713 ,  A01N47/34 ,  A01N43/653 ,  A01N43/80

CPC classification number: A01N57/24 ,  A01N43/653 ,  A01N43/713 ,  A01N43/80 ,  A01N47/28 ,  A01N47/34

Abstract: Use of N-(tetrazol-4-yl)- or N-(triazol-3-yl)arylcarboxamides of formula (I) or salts thereof for controlling unwanted plants in areas of transgenic crop plants being tolerant to HPPD inhibitor herbicides by containing one or more chimeric gene(s) comprising (I) a DNA sequence encoding hydroxyphenylpyruvate dioxygenase (HPPD) derived from a member of a group of organisms consisting of (a) Avena, (b) Pseudomonas, (c) Synechococcoideae, (d) Blepharismidae, (e) Rhodococcus, (f) Picrophilaceae, (g) Kordia, or (II) comprising one or more mutated DNA sequences of HPPD encoding genes of the before defined organisms.

Abstract translation: 式（I）的N-（四唑-4-基） - 或N-（三唑-3-基）芳基羧酰胺或其盐用于控制对HPPD抑制剂除草剂具有耐受性的转基因作物植物区域中的不想要的植物， 或更多的嵌合基因，其包含（I）编码由（a）Avena，（b）假单胞菌，（c）集落藻科，（d）睑炎科（A））组成的一组生物的成员的羟基苯丙酮酸双加氧酶（HPPD）的DNA序列 ，（e）红球菌属，（f）Picrophilaceae，（g）Kordia或（II），其包含一个或多个经过定义的生物体的HPPD编码基因的突变的DNA序列。

公开(公告)号：US20110197308A1

公开(公告)日：2011-08-11

申请号：US12977126

申请日：2010-12-23

Applicant: Fabien Poree ,  Bernd Laber ,  Nathalie Knittel-Ottleben ,  Gudrun Lange ,  Arno Schulz ,  Ruediger Hain

Inventor： Fabien Poree ,  Bernd Laber ,  Nathalie Knittel-Ottleben ,  Gudrun Lange ,  Arno Schulz ,  Ruediger Hain

IPC: A01H1/00 ,  C07H21/04 ,  C12N15/82 ,  C12N5/10 ,  A01H5/00 ,  A01H5/10 ,  A01N39/02 ,  A23L1/48 ,  C11B1/00

CPC classification number: C12N15/8274 ,  C12N9/001 ,  C12N9/0069 ,  C12Y103/01012 ,  C12Y113/11027

Abstract: The present invention relates to nucleic acid sequences encoding a hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27, abbreviated herein as HPPD) obtained from bacteria belonging to the genus Kordia, as well as the proteins encoded thereby, and to a chimeric gene which comprises such nucleic acid sequence, and to the use of such nucleic acid sequences, proteins or chimeric genes for obtaining plants which are tolerant to HPPD inhibitor herbicides.

Abstract translation: 本发明涉及从属于科迪亚属的细菌获得的编码羟基苯基丙酮酸双加氧酶（EC 1.13.11.27，本文缩写为HPPD）的核酸序列，以及由此编码的蛋白质以及包含该核酸的嵌合基因 序列，以及使用这种核酸序列，蛋白质或嵌合基因来获得对HPPD抑制剂除草剂具有耐受性的植物。

公开(公告)号：US06630331B1

公开(公告)日：2003-10-07

申请号：US09424378

申请日：1999-11-23

Applicant: Christopher Abell ,  Alison Gail Smith ,  Ulrich Genschel ,  Bernd Laber

Inventor： Christopher Abell ,  Alison Gail Smith ,  Ulrich Genschel ,  Bernd Laber

IPC: C12N900

CPC classification number: C12N9/93 ,  A01N61/00 ,  C12N15/8274 ,  G01N33/573

Abstract: An isolated DNA molecule encoding a protein from a plant, which protein has pantothenate synthetase activity; a non-naturally occuring chimeric gene comprising a promoter operably linked to a DNA molecule encoding a protein from a plant having pantothenate synthetase activity; a recombinant vector comprising the chimeric gene wherein the vector is capable of being stably transformed into host cell, a host cell stably transformed with a vector wherein the host cell is capable of expressing the DNA molecule; a method for assaying a protein having pantothenate synthetase activity; the use as herbicides of compounds which inhibit pantothenate synthetase, and a herbicidal composition, comprising one or more active ingredients which show significant pantothenate synthetase inhibition in an assay, are disclosed. The invention relates to plant enzymatic activity, and aspects therefor, involved in the biosynthesis of coenzyme A. The invention particularly relates to the plant enzyme known either as pantoate B-alanine ligase, pantoate activating enzyme or pantothenate synthetase (PS).

Abstract translation: 编码来自植物的蛋白质的分离的DNA分子，该蛋白质具有泛酸合成酶活性; 非天然存在的嵌合基因，其包含与编码具有泛酸合成酶活性的植物的蛋白质的DNA分子可操作地连接的启动子; 包含嵌合基因的重组载体，其中所述载体能够稳定转化到宿主细胞中，宿主细胞用宿主细胞能够表达DNA分子的载体稳定转化; 测定具有泛酸合成酶活性的蛋白质的方法; 公开了作为抑制泛酸合成酶的化合物的除草剂的用途，以及除草组合物，其包含在测定中显示出显着的泛酸合成酶抑制的一种或多种活性成分。本发明涉及植物酶活性及其方面， 辅酶A的生物合成。本发明特别涉及已知有泛酸B-丙氨酸连接酶，泛酸活化酶或泛酸合成酶（PS）的植物酶。