公开(公告)号：US20070225270A1

公开(公告)日：2007-09-27

申请号：US11710644

申请日：2007-02-23

Applicant: Timothy Guzi ,  Kamil Paruch ,  Michael Dwyer ,  Marc Labroli ,  Kartik Keertikar

Inventor： Timothy Guzi ,  Kamil Paruch ,  Michael Dwyer ,  Marc Labroli ,  Kartik Keertikar

IPC: A61K31/551 ,  A61K31/5377 ,  A61K31/519 ,  C07D487/04 ,  A61K31/541

CPC classification number: C07D487/04 ,  Y02P20/582

Abstract: In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.

公开(公告)号：US20070072881A1

公开(公告)日：2007-03-29

申请号：US11542920

申请日：2006-10-04

Applicant: Timothy Guzi ,  Kamil Paruch ,  Michael Dwyer ,  Marc Labroli ,  Kartik Keertikar

Inventor： Timothy Guzi ,  Kamil Paruch ,  Michael Dwyer ,  Marc Labroli ,  Kartik Keertikar

IPC: A61K31/519 ,  C07D487/04

CPC classification number: C07D487/04

Abstract: In its many embodiments, the present invention provides a class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases (CDKs), methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.