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11.
公开(公告)号:US06660854B2
公开(公告)日:2003-12-09
申请号:US10310887
申请日:2002-12-06
Applicant: Tai-Au Lee , Nam-Jin Park , Ja-Heouk Khoo , Byung-Cheol Lee
Inventor: Tai-Au Lee , Nam-Jin Park , Ja-Heouk Khoo , Byung-Cheol Lee
IPC: C07H19056
CPC classification number: C07H19/056 , C07H1/00 , Y02P20/55
Abstract: Provided are a process for preparing &bgr;-D-ribofuranose derivatives, which are useful as an intermediate for the preparation of ribavirin. The process can be performed under a mild condition, in the presence of a catalyst selected from the group consisting of methanesulfonic acid, benzenesulfonic acid and p-toluenesulfonic acid.
Abstract translation: 提供了制备β-D-呋喃核糖衍生物的方法,其可用作制备利巴韦林的中间体。 该方法可以在温和条件下,在选自甲磺酸,苯磺酸和对甲苯磺酸的催化剂存在下进行。