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公开(公告)号：US3452061A
公开(公告)日：1969-06-24
申请号：US3452061D
申请日：1968-01-29
Applicant: AMERICAN HOME PROD
Inventor： WENDT GERHARD R , LEDIG KURT W
IPC: C07J41/00 , C07C169/12 , C07C169/02
CPC classification number: C07J41/0072
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公开(公告)号：US3387006A
公开(公告)日：1968-06-04
申请号：US34081964
申请日：1964-01-28
Applicant: AMERICAN HOME PROD
Inventor： WENDT GERHARD R , LEDIG KURT W
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公开(公告)号：US3366652A
公开(公告)日：1968-01-30
申请号：US31046563
申请日：1963-09-20
Applicant: AMERICAN HOME PROD
Inventor： WENDT GERHARD R , LEDIG KURT W
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14.发明授权D-17beta-(3-aminopropoxy)-3-alkoxyestra-1, 3, 5(10)-trienes and urea derivatives thereof 失效D-17β-（3-氨基丙氧基）-3-烷氧基雌甾-1,3,5（10） - 三烯及其脲衍生物
公开(公告)号：US3312721A
公开(公告)日：1967-04-04
申请号：US48622765
申请日：1965-09-09
Applicant: AMERICAN HOME PROD
Inventor： WENDT GERHARD R , LEDIG KURT W
IPC: C07J41/00
CPC classification number: C07J41/0094 , C07J41/0072
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公开(公告)号：US3311626A
公开(公告)日：1967-03-28
申请号：US56081766
申请日：1966-06-27
Applicant: AMERICAN HOME PROD
Inventor： WENDT GERHARD R , LEDIG KURT W
IPC: C07D241/38
CPC classification number: C07D241/38
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Patent Agency Ranking16.发明授权
公开(公告)号：US3261853A
公开(公告)日：1966-07-19
申请号：US40868964
申请日：1964-11-03
Applicant: AMERICAN HOME PROD
Inventor： WENDT GERHARD R , LEDIG KURT W
IPC: C07J41/00
CPC classification number: C07J41/0072 , Y10S514/866
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17.发明授权17alpha-(3-substituted aminopropyl)-17-hydroxyestra-3-one-steroids and process for preparing same 失效17α-（3-取代氨基丙基）-17-羟雌甾-3-酮类固醇及其制备方法
公开(公告)号：US3184486A
公开(公告)日：1965-05-18
申请号：US28971763
申请日：1963-06-21
Applicant: AMERICAN HOME PROD
Inventor： WENDT GERHARD R , LEDIG KURT W
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公开(公告)号：US3880866A
公开(公告)日：1975-04-29
申请号：US35237573
申请日：1973-04-18
Applicant: AMERICAN HOME PROD
Inventor： HERBST DAVID R , LEDIG KURT W
IPC: C07D471/22 , C07D57/04
CPC classification number: C07D471/22
Abstract: Compound of the formulae:
WHERE R is hydrogen, alkyl of from 1 to 5 carbon atoms, or allyl; R1 is methyl, ethyl, or n-propyl; R2 is alkyl of from 1 to 5 carbon atoms or allyl; and n is 1 or 2, or the pharmacologically acceptable acid addition salts thereof have analgesic activity.Abstract translation: 化合物的配方：
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公开(公告)号：US3644436A
公开(公告)日：1972-02-22
申请号：US3644436D
申请日：1969-04-30
Applicant: AMERICAN HOME PROD
Inventor： WENDT GERHARD R , LEDIG KURT W , TELLER DANIEL M
IPC: C07J41/00 , C07C169/00
CPC classification number: C07J41/0005
Abstract: THE DISCLOSURE IS DIRECTED TO BIS(AMIDINOHYDRAZONES) OF GONA-3,17-DINORPREGNA-3,20-DIONES. THE COMPOUNDS HAVE DARDIOTONIC ACTIVITY.
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20.发明授权Semicarbazones and thiosemicarbazones of 17alpha-substituted 3-keto-steroids 失效17ALPHA取代的3-酮酯的半胱氨酸和硫代硫酸钠
公开(公告)号：US3642842A
公开(公告)日：1972-02-15
申请号：US3642842D
申请日：1968-12-23
Applicant: AMERICAN HOME PROD
Inventor： BEGANY ALBERT J , LEDIG KURT W , OLIVER DONALD W , WENDT GERHARD R
IPC: C07J41/00 , C07J63/00 , C07C169/20
CPC classification number: C07J63/008 , C07J41/0005
Abstract: 13-ALKYL-17X-SUBSTITUTED - 17 - HYDROXYGON-4-EN-3-ONE, SEMICARBAXONES AND THIOSEMICARBAZONES, $4,6,8(14),9 AND 11 DEHYDRO ANALOGS, AND D-HOMO ANALOGS THEREOF, OPTIONALLY SUBSTITUTED BY METHYL AT POSTIONS 1,2,4,6,7 AND 11, ALKANOYL AT POSTION 17, BY ALKYL, ARYL, ARYLALKYL AND ALKYLARYL IN THE SEMICARBAZONE OR THIOSEMICARBAZONE GROUP, AND BY A 17X-ALKYL GROUP OR BY METHYL OR HAOLGEN IN A 17X-ETHYNYL GROUP (I) ARE PROVIDED BY CONDENSING THE CORRESPONDING 3-KETOSTEROID (II) WITH THE CORRESPONDING SEMICARBAZIDE OR THIOSEMICARBAZIDE (III). COMPOUNDS (I) ARE PHARMACOLOGICALLY ACTIVE IN WARM BLOODED LOWER ANIMALS AS BRONOCHODILATORS AND AS ANTI-INFLAMMATORY AGENTS.
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