公开(公告)号：US11564981B2

公开(公告)日：2023-01-31

申请号：US17474797

申请日：2021-09-14

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Kenneth Roland ,  Andrew Diamos ,  Hugh Mason

IPC: A61K39/08 ,  A61P31/04 ,  C12N15/74 ,  C12N15/82 ,  A61K39/00

Abstract: In certain embodiments, the present invention provides a poultry vaccine comprising an antigenic protein comprising a PlcC protein unit that is operably linked to a peptide linker that is operably linked to a NetB protein unit, where the vaccine is effective in stimulating a protective cellular and/or humoral immune response to C. perfringens. Methods are also provided for making the vaccine and for vaccinating poultry by administering such a vaccine.