专利检索 ap:("Ali Ebrahimi Afrouzi" OR "Scott McDonald" OR "Masoud Nasiri Sarvi") AND inv:"Scott McDonald" 第 2 页

11.

发明申请
Memantine for the treatment of mild and mild to moderate Alzheimer's disease 审中-公开
标题翻译：美金刚治疗轻度和轻度至中度阿尔茨海默病

公开(公告)号：US20060020042A1

公开(公告)日：2006-01-26

申请号：US11030584

申请日：2005-01-05

申请人： Scott McDonald , Ivan Gergel , Steven Potkin , Albrecht Stoffler , Yvonne Wirth , Hans-Joerg Moebius

发明人： Scott McDonald , Ivan Gergel , Steven Potkin , Albrecht Stoffler , Yvonne Wirth , Hans-Joerg Moebius

IPC分类号： A61K31/13

CPC分类号： A61K31/13

摘要： The present invention provides a method for the treatment, prevention, or delay of progression of mild, or mild-to-moderate Alzheimer's disease, by administering an effective dose of memantine. The present invention also provides a method for preventing the decrease in glucose metabolism in the cortical and sub-cortical regions of the brain in subjectes with mild, or mild-to-moderate Alzheimer's disease.

摘要翻译： 本发明提供了通过施用有效剂量的美金刚来治疗，预防或延缓轻度或轻度至中度阿尔茨海默氏病的进展的方法。本发明还提供了一种用于在具有轻度或轻度至中度阿尔茨海默氏病的受试者中防止脑皮质和亚皮质区域中葡萄糖代谢降低的方法。

12.

发明申请
Memantine for the prevention or reduction of suicidality and for treatment of major depression associated with suicidality 审中-公开
标题翻译：美加哥预防或减少自杀和治疗与自杀相关的重大抑郁症

公开(公告)号：US20050282911A1

公开(公告)日：2005-12-22

申请号：US11006487

申请日：2004-12-06

申请人： Heikki Hakkarainen , Scott McDonald , Charles Flicker

发明人： Heikki Hakkarainen , Scott McDonald , Charles Flicker

IPC分类号： A61K31/13

CPC分类号： A61K31/13

摘要： The present invention relates to the treatment of major depressive disorder (MDD), and the prevention of suicidality associated therewith, using the uncompetitive NMDA receptor antagonist memantine.

摘要翻译： 本发明涉及使用非竞争性NMDA受体拮抗剂美金刚治疗重度抑郁障碍（MDD）和预防与之相关的自杀。