公开(公告)号：US20110201634A1

公开(公告)日：2011-08-18

申请号：US13057247

申请日：2009-06-15

申请人： Virinder Singh Parmar ,  Hanumanthrao Guru Raj ,  Ashok Kumar Prasad

发明人： Virinder Singh Parmar ,  Hanumanthrao Guru Raj ,  Ashok Kumar Prasad

IPC分类号： A61K31/513 ,  C07D239/22 ,  A61P9/00 ,  A61P7/02

CPC分类号： C07D239/22

摘要： The present invention relates to a dihydropyrimidinone compound of formula (I) wherein X represents O, S, etc. and R′ represents alkyl, alkoxy, thioalkyl, thioalkyloxy, phenyl, substituted phenyl, phenyloxy, substituted phenyloxy, amino, monosubstitutedamino, disubstitutedamino, aryl, heteroaryl, aryloxy, heteroaryloxy, halo; R″ represents alkoxy, phenyloxy, substituted phenyloxy, aryloxy, heteroaryloxy, halo, NR1R2 and Rn represents OR1, NH2, SR1, NR1R2; R1, R2=H, alkyl, phenyl, aryl, OCOR3, SCOR3, NHCOR3, NR1COR3; R3 represents alkyl, phenyl, aryl, heteroaryl.

摘要翻译： 本发明涉及式（I）的二氢嘧啶酮化合物，其中X表示O，S等，R'表示烷基，烷氧基，硫代烷基，硫代烷氧基，苯基，取代的苯基，苯氧基，取代的苯氧基，氨基，单取代的氨基，二取代的氨基， 芳基，杂芳基，芳氧基，杂芳氧基，卤素; R“表示烷氧基，苯氧基，取代的苯氧基，芳氧基，杂芳氧基，卤素，NR1R2和Rn表示OR1，NH2，SR1，NR1R2; R1，R2 = H，烷基，苯基，芳基，OCOR3，SCOR3，NHCOR3，NR1COR3; R3表示烷基，苯基，芳基，杂芳基。