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公开(公告)号:US20160061599A1
公开(公告)日:2016-03-03
申请号:US14841198
申请日:2015-08-31
发明人: Qingguo Zeng , Ping Jia , Charulatha Ramanathan , Lijun Yu , Jeff Burrell , Brian George , Qing Lu , Ryan Bokan , Soniya Bhojwani
摘要: This disclosure relates to localization and tracking of an object. As one example, measurement data can be stored in memory to represent measured electrical signals at each of a plurality of known measurement locations in a given coordinate system in response to an applied signal at an unknown location in the given coordinate system. A dipole model cost function has parameters representing a dipole location and moment corresponding to the applied signal. A boundary condition can be imposed on the dipole model cost function. The unknown location in the given coordinate system, corresponding to the dipole location, can then be determined based on the stored measurement data and the dipole model cost function with the boundary condition imposed thereon.
摘要翻译: 本公开涉及对象的定位和跟踪。 作为一个示例,响应于给定坐标系中未知位置处的施加信号,测量数据可以存储在存储器中以在给定坐标系中的多个已知测量位置的每一个处表示测量的电信号。 偶极子模型成本函数具有表示与施加的信号相对应的偶极位置和力矩的参数。 可以对偶极子模型成本函数施加边界条件。 然后,可以基于存储的测量数据和施加有边界条件的偶极子模型成本函数来确定给定坐标系中对应于偶极位置的未知位置。
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公开(公告)号:US20150216438A1
公开(公告)日:2015-08-06
申请号:US14614219
申请日:2015-02-04
发明人: RYAN BOKAN , Charulatha Ramanathan , Ping Jia , Maria Strom , Qingguo Zeng
IPC分类号: A61B5/0452 , A61B5/0432 , A61B5/0245 , A61B5/04 , A61B5/024 , A61B5/00 , A61B5/044
CPC分类号: A61B5/0452 , A61B5/02405 , A61B5/0245 , A61B5/04012 , A61B5/0402 , A61B5/042 , A61B5/044 , A61B5/06 , A61B5/066 , A61B5/4836 , A61B5/7264 , A61B5/743
摘要: A method can include analyzing non-invasive electrical data for a region of interest (ROI) of a patient's anatomical structure to identify one or more zones within the ROI that contain at least one mechanism of distinct arrhythmogenic electrical activity. The method also includes analyzing invasive electrical data for a plurality of signals of interest at different spatial sites within each of the identified zones to determine intracardiac signal characteristics for the plurality of sites within each respective zone. The method also includes generating an output that integrates the at least one mechanism of distinct arrhythmogenic electrical activity for the one or more zones with intracardiac signal characteristics for the plurality of sites within each respective zone.
摘要翻译: 方法可以包括分析患者解剖结构的感兴趣区域(ROI)的非侵入式电气数据,以识别ROI内包含至少一种不同致心律不良电活动的机制的一个或多个区域。 该方法还包括分析在每个识别的区域内的不同空间位置处的感兴趣的多个信号的侵入性电数据,以确定每个相应区域内的多个位点的心内信号特征。 该方法还包括产生一个输出,该输出将一个或多个区域的不同致心律失常电活动的至少一种机制与每个相应区域内的多个位点的心内信号特征相集成。
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公开(公告)号:US20140200467A1
公开(公告)日:2014-07-17
申请号:US14156951
申请日:2014-01-16
发明人: Maria Strom , Qingguo Zeng , Remi Dubois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Brian P. George
CPC分类号: A61B5/7282 , A61B5/0042 , A61B5/0044 , A61B5/0402 , A61B5/044 , A61B5/0476 , A61B5/7425
摘要: A method can include storing a plurality of data sets including values computed for each of a plurality of points for a given spatial region of tissue, the values in each of the data sets characterizing electrical information for each respective point of the plurality of points for a different time interval. The method can also include combining the values computed for each of a plurality of points in a first interval, corresponding to a first map, with the values for computed for each of the respective plurality of points in another interval and to normalize the combined values relative to a common scale. The method can also include generating a composite map for the given spatial region based on the combined values that are normalized.
摘要翻译: 一种方法可以包括存储多个数据集,包括为组织的给定空间区域的多个点中的每一个计算的值,每个数据集中的值表征多个点中的每个点的电信息, 不同的时间间隔。 该方法还可以包括将对应于第一映射的第一间隔中的多个点中的每个点计算的值与为另一间隔中的相应多个点中的每个点计算的值相组合,并且将组合值相对于 达到共同的规模。 该方法还可以包括基于归一化的组合值来生成给定空间区域的复合图。
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公开(公告)号:US11179054B2
公开(公告)日:2021-11-23
申请号:US16033971
申请日:2018-07-12
IPC分类号: A61B5/0536 , A61B5/00 , A61B6/03 , A61B6/00 , G06T7/33 , A61B34/20 , A61B90/00 , G06T7/00 , A61B5/06 , G06T7/73 , A61B5/282 , A61B34/10
摘要: A method includes placing a set of electrodes on a body surface of a patient's body. The method also includes digitizing locations for the electrodes across the body surface based on one or more image frames using range imaging and/or monoscopic imaging. The method also includes estimating locations for hidden ones of the electrodes on the body surface not visible during the range imaging and/or monoscopic imaging. The method also includes registering the location for the electrodes on the body surface with predetermined geometry information that includes the body surface and an anatomical envelope within the patient's body. The method also includes storing geometry data in non-transitory memory based on the registration to define spatial relationships between the electrodes and the anatomical envelope.
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公开(公告)号:US10806359B2
公开(公告)日:2020-10-20
申请号:US15498992
申请日:2017-04-27
发明人: Qingguo Zeng , Qing Lou , Ryan M. Bokan , Ping Jia , Connor S. Edel , Charulatha Ramanathan
摘要: One or more non-transitory computer-readable media have instructions executable by a processor and programmed to perform a method. The method includes analyzing the electrical data to locate one or more wave front lines over a given time interval. The electrical data represents electrophysiological signals distributed across a cardiac envelope for one or more time intervals. A respective trajectory is determined for each wave end of each wave front line that is located across the cardiac envelope over the given time interval. A set of connected trajectories are identified based on a duration that the trajectories are connected to each other by a respective wave front line during the given time interval. A connectivity association is characterized for the trajectories in the set of connected trajectories.
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公开(公告)号:US10568540B2
公开(公告)日:2020-02-25
申请号:US14867716
申请日:2015-09-28
发明人: Ping Jia , Qingguo Zeng , Charulatha Ramanathan , Ryan Bokan
摘要: An example method includes applying a localization signal to a source electrode positioned within a conductive volume and a ground electrode at a known location. Electrical activity is sensed at a plurality of sensor electrodes distributed across an outer surface of the conductive volume. The locations of each of the sensor electrodes and the location of the ground electrode being stored in memory as part of geometry data. The electrical activity sensed at each of the sensor electrodes is stored in the memory as electrical measurement data. The method also includes computing a location of the source electrode by minimizing a difference between respective pairs of source voltages determined for the plurality of sensor electrodes. The source voltage for each of the sensor electrodes is determined based on the electrical measurement data and the geometry data.
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公开(公告)号:US10376173B2
公开(公告)日:2019-08-13
申请号:US15498719
申请日:2017-04-27
发明人: Brian P. George , Meredith E. Stone , Qingguo Zeng , Qing Lou , Connor S. Edel , Ping Jia , Jeffrey B. Adair , Vladimir A. Turovskiy , Matthew J. Sabo , Ryan M. Bokan , Ketal C. Patel , Charulatha Ramanathan , John E. Anderson , Andrew E. Hoover , Cheng Yao
IPC分类号: A61B5/00 , A61B5/0456 , A61B5/04 , A61B5/0408 , A61B5/0452
摘要: An example method includes performing amplitude-based detection to determine location of R-peaks for a plurality of electrograms. The method also includes performing wavelet-based detection to determine location of R-peaks for the plurality of electrograms. The method also includes adjusting the location of the R-peaks determined by the wavelet-based detection of R-peaks based on the location of R-peaks determined by the amplitude-based detection of R-peaks. The method also includes storing, in memory, R-peak location data to specify R-peak locations for the plurality of electrograms based on the adjusting.
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公开(公告)号:US09974462B2
公开(公告)日:2018-05-22
申请号:US15048835
申请日:2016-02-19
发明人: Vivek Jayan , Ping Jia , Ryan Bokan , Charulatha Ramanathan , Qingguo Zeng , Torsten Konrad
IPC分类号: A61B5/04 , A61B5/046 , A61B5/0402 , A61B5/00 , A61B18/12 , A61B5/18 , A61B5/0408 , A61N1/365 , A61B18/14 , A61B18/00 , A61B18/02
CPC分类号: A61B5/046 , A61B5/04012 , A61B5/0402 , A61B5/0408 , A61B5/18 , A61B5/4836 , A61B5/7275 , A61B18/1206 , A61B18/1492 , A61B2018/00357 , A61B2018/00363 , A61B2018/00577 , A61B2018/0072 , A61B2018/00767 , A61B2018/00994 , A61B2018/0212 , A61N1/365
摘要: A system includes an input to receive at least one electrophysiological signal representing cardiac electrical activity measured from a body surface of a patient. The system also includes a signal processor to analyze the at least one electrophysiological signal and compute a score having a value to indicate a likelihood of arrhythmogenic activity, the score being computed as a function of at least two of cycle length, amplitude and polarity of the at least one signal.
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公开(公告)号:US09737267B2
公开(公告)日:2017-08-22
申请号:US14156951
申请日:2014-01-16
发明人: Maria Strom , Qingguo Zeng , Remi Dubois , Ping Jia , Ryan Bokan , Venkatesh Vasudevan , Charulatha Ramanathan , Brian P. George
IPC分类号: A61B5/00 , A61B5/0402 , A61B5/044 , A61B5/0476
CPC分类号: A61B5/7282 , A61B5/0042 , A61B5/0044 , A61B5/0402 , A61B5/044 , A61B5/0476 , A61B5/7425
摘要: A method can include storing a plurality of data sets including values computed for each of a plurality of points for a given spatial region of tissue, the values in each of the data sets characterizing electrical information for each respective point of the plurality of points for a different time interval. The method can also include combining the values computed for each of a plurality of points in a first interval, corresponding to a first map, with the values for computed for each of the respective plurality of points in another interval and to normalize the combined values relative to a common scale. The method can also include generating a composite map for the given spatial region based on the combined values that are normalized.
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公开(公告)号:US20230036977A1
公开(公告)日:2023-02-02
申请号:US17840256
申请日:2022-06-14
发明人: Qingguo Zeng , Timothy G. Laske , Qing Lou
摘要: In an example, a signal segment evaluator can be programmed to evaluate a morphology of at least one electrophysiological signal to identify a signal segment of interest. The morphology of the signal segment of interest can be indicative of an electrophysiological event of a patient during a respective time interval. A reconstruction engine can be programmed to reconstruct electrophysiological signals on a surface of interest within a body of the patient based on the electrophysiological signals measured from an outer surface of the patient and geometry data representing an anatomy of the patient. A map generator can be programmed to generate a map representing the reconstructed electrophysiological signals on the surface of interest for the respective time interval of the signal segment of interest. A target generator can be programmed to identify a target site within the patient's body based on the map for the electrophysiological event.
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