公开(公告)号：US08669279B2

公开(公告)日：2014-03-11

申请号：US13874575

申请日：2013-05-01

Applicant: Cephalon, Inc.

Inventor： Martin Ian Cooper ,  Laurent D. Courvoisier ,  Mark Eddleston ,  Robert E. McKean

IPC: C07D235/16

CPC classification number: A61K31/4184 ,  A61K9/0019 ,  A61K9/14 ,  A61K9/19 ,  A61K47/26 ,  C07D235/16

Abstract: Novel solid forms of bendamustine hydrochloride are described, as well as methods of their preparation and use.

公开(公告)号：US20170071913A1

公开(公告)日：2017-03-16

申请号：US15359777

申请日：2016-11-23

Applicant: Cephalon, Inc.

Inventor： Martin Ian Cooper ,  Laurent D. Courvoisier (Deceased) ,  Mark Eddleston ,  Robert E. McKean

IPC: A61K31/4184 ,  A61K47/26 ,  A61K9/00

CPC classification number: A61K31/4184 ,  A61K9/0019 ,  A61K9/14 ,  A61K9/19 ,  A61K47/26 ,  C07D235/16

Abstract: Novel solid forms of bendamustine hydrochloride are described, as well as methods of their preparation and use.

Abstract translation: 描述了新型固体形式的盐酸苯达莫司汀，以及它们的制备和使用方法。