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公开(公告)号:US10973891B2
公开(公告)日:2021-04-13
申请号:US16359598
申请日:2019-03-20
IPC分类号: C07K14/745 , A61K38/36 , A61P7/04 , A61K38/57 , A61K45/06
摘要: The present invention relates to a contact activation system inhibitor, preferably a C1INH, for use in the treatment and/or prevention of remote ischemia-reperfusion injury (IRI), comprising administering the contact activation system inhibitory to an individual.
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公开(公告)号:US20200062863A1
公开(公告)日:2020-02-27
申请号:US16674131
申请日:2019-11-05
申请人: CSL Behring GmbH , CSL Ltd.
发明人: Con Panousis , Veronika Rayzman , Andrew Nash , Michael Wilson , Stefan Schmidbauer , Marc Nolte
摘要: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.
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公开(公告)号:US10513560B2
公开(公告)日:2019-12-24
申请号:US15822559
申请日:2017-11-27
申请人: CSL Behring GmbH , CSL Ltd.
发明人: Con Panousis , Veronika Rayzman , Andrew Nash , Michael Wilson , Stefan Schmidbauer , Marc Nolte
IPC分类号: A61K39/395 , C07K16/40 , C07K16/36 , A61K39/00
摘要: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.
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公开(公告)号:US10286047B2
公开(公告)日:2019-05-14
申请号:US14773020
申请日:2014-03-07
申请人: UNIVERSITÄT BERN , CSL BEHRING GMBH
摘要: The present invention relates to a contact activation system inhibitor, preferably a C1INH, for use in the treatment and/or prevention of remote ischemia-reperfusion injury (IRI), comprising administering the contact activation system inhibitory to an individual.
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公开(公告)号:US09856325B2
公开(公告)日:2018-01-02
申请号:US15343401
申请日:2016-11-04
申请人: CSL Behring GmbH , CSL Ltd.
发明人: Con Panousis , Veronika Rayzman , Andrew Nash , Michael Wilson , Stefan Schmidbauer , Marc Nolte
CPC分类号: C07K16/40 , A61K2039/505 , C07K16/36 , C07K2317/21 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12Y304/21038
摘要: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.
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公开(公告)号:US20170137536A1
公开(公告)日:2017-05-18
申请号:US15343447
申请日:2016-11-04
申请人: CSL Behring GmbH , CSL Ltd.
发明人: Con Panousis , Veronika Rayzman , Andrew Nash , Michael Wilson , Stefan Schmidbauer , Marc Nolte
IPC分类号: C07K16/40
CPC分类号: C07K16/40 , A61K2039/505 , C07K16/36 , C07K2317/21 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C12Y304/21038
摘要: The invention relates to inhibitory anti-factor XII/FXIIa antibodies and methods of their use.
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