公开(公告)号：US20200155562A1

公开(公告)日：2020-05-21

申请号：US16660339

申请日：2019-10-22

Applicant: Epizyme, Inc.

Inventor： Kevin W. KUNTZ ,  Richard CHESWORTH ,  Kenneth W. DUNCAN ,  Heike KEILHACK ,  Natalie WARHOLIC ,  Christine KLAUS ,  Sarah K. KNUTSON ,  Timothy J. N. WIGLE ,  Masashi SEKI ,  Syuji SHIROTORI ,  Satoshi KAWANO

IPC: A61K31/5377 ,  A61K31/553 ,  A61K31/551 ,  A61K31/506 ,  A61K31/496 ,  A61K31/4709 ,  A61K31/4545 ,  A61K31/444 ,  A61K31/4439 ,  A61K31/4436 ,  A61K31/4433 ,  A61K31/443 ,  A61K31/4412 ,  C07D405/14 ,  C07D213/64 ,  C07D491/107 ,  C07D491/08 ,  C07D417/12 ,  C07D413/12 ,  C07D409/12 ,  C07D405/12 ,  C07D401/12 ,  C07D498/08

Abstract: The present invention relates to aryl- or heteroaryl-substituted benzene compounds. The present invention also relates to pharmaceutical compositions containing these compounds and methods of treating cancer by administering these compounds and pharmaceutical compositions to subjects in need thereof. The present invention also relates to the use of such compounds for research or other non-therapeutic purposes.