公开(公告)号：US20190262481A1

公开(公告)日：2019-08-29

申请号：US16145115

申请日：2018-09-27

Applicant: GENERAL ELECTRIC COMPANY ,  AFFIBODY AB

Inventor： Faisal Ahmed Syud ,  Brian Duh-Lan Lee ,  Rong Zhang ,  Peter Brian Iveson ,  Paul Schaffer ,  Tove Simonsson ,  Elin Gunneriusson ,  Fredrik Frejd ,  Lars Abrahmsen ,  Joachim Feldwisch ,  Nina Herne ,  Christofer Lendel

IPC: A61K51/08 ,  C07K14/71

Abstract: Imaging agents comprising an isolated polypeptide conjugated with a radionuclide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents.

公开(公告)号：US10159760B2

公开(公告)日：2018-12-25

申请号：US15083424

申请日：2016-03-29

Applicant: General Electric Company ,  AFFIBODY AB

Inventor： Faisal Ahmed Syud ,  Brian Duh-Lan Lee ,  Rong Zhang ,  Peter Brian Iveson ,  Paul Schaffer ,  Tove Simonsson ,  Elin Gunneriusson ,  Fredrik Frejd ,  Lars Abrahmsen ,  Joachim Feldwisch ,  Nina Herne ,  Christofer Lendel

IPC: A61K51/00 ,  A61M36/14 ,  A61K51/08 ,  C07K14/71

Abstract: Imaging agents comprising an isolated polypeptide conjugated with a radionucleide and a chelator; wherein the isolated polypeptide binds specifically to HER2, or a variant thereof; and methods for preparing and using these imaging agents.