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公开(公告)号:US20200262932A1
公开(公告)日:2020-08-20
申请号:US16777053
申请日:2020-01-30
Applicant: GENMAB A/S
Inventor: Aran Frank LABRIJN , Joyce I. MEESTERS , Ewald T. J. VAN DEN BREMER , Joost J. NEIJSSEN , Patrick VAN BERKEL , Bart DE GOEIJ , Tom VINK , Jan VAN DE WINKEL , Janine SCHUURMAN , Paul PARREN
Abstract: Novel heterodimeric antibody-Fc-containing proteins, such as bispecific antibodies, and novel methods for producing such proteins
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公开(公告)号:US20170369590A1
公开(公告)日:2017-12-28
申请号:US15599393
申请日:2017-05-18
Applicant: GENMAB A/S
Inventor: Bart DE GOEIJ , Patrick VAN BERKEL , Kristin STRUMANE , Aran Frank LABRIJN , Joost J. NEIJSSEN , Joyce I. MEESTERS , Paul PARREN , Janine SCHUURMAN
IPC: C07K16/32 , A61K45/06 , A61K47/68 , A61K39/395 , A61K39/00
CPC classification number: C07K16/32 , A61K39/395 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K47/6855 , A61K47/6879 , A61K2039/505 , C07K16/1063 , C07K16/2809 , C07K16/2863 , C07K16/2887 , C07K16/468 , C07K2317/21 , C07K2317/24 , C07K2317/30 , C07K2317/31 , C07K2317/33 , C07K2317/41 , C07K2317/526 , C07K2317/53 , C07K2317/55 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/77 , C07K2317/92 , C07K2317/94
Abstract: Bispecific antibodies which comprise antigen-binding regions binding to two different epitopes of human epidermal growth factor receptor 2 (HER2), and related antibody-based compositions and molecules, are disclosed. Pharmaceutical compositions comprising the antibodies and methods of preparing and using the antibodies are also disclosed.
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13.HETERODIMERIC ANTIBODY FC-CONTAINING PROTEINS AND METHODS FOR PRODUCTION THEREOF 审中-公开
Title translation: 含杂交抗体的含FC蛋白质及其生产方法公开(公告)号:US20160046727A1
公开(公告)日:2016-02-18
申请号:US14830336
申请日:2015-08-19
Applicant: GENMAB A/S
Inventor: Aran Frank LABRIJN , Joyce I. MEESTERS , Ewald T. J. VAN DEN BREMER , Joost J. NEIJSSEN , Patrick VAN BERKEL , Bart DE GOEIJ , Tom VINK , Jan VAN DE WINKEL , Janine SCHUURMAN , Paul PARREN
CPC classification number: C07K16/468 , A61K2039/505 , C07K16/1063 , C07K16/2809 , C07K16/2863 , C07K16/2887 , C07K16/32 , C07K16/40 , C07K2317/14 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/41 , C07K2317/526 , C07K2317/53 , C07K2317/55 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/6854
Abstract: Novel heterodimeric antibody-Fc-containing proteins, such as bispecific antibodies, and novel methods for producing such proteins
Abstract translation: 新型异二聚抗体-Fc的蛋白质,例如双特异性抗体,以及用于产生这种蛋白质的新方法
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