公开(公告)号：US20160310611A1

公开(公告)日：2016-10-27

申请号：US15104388

申请日：2014-12-16

Applicant: GENENTECH INC. ,  MEDIMMUNE LIMITED

Inventor： John FLYGARE ,  Janet GUNZNER-TOSTE ,  Thomas PILLOW ,  Brian SAFINA ,  Vishal VERMA ,  Binqing WEI ,  Guiling ZHAO ,  Leanna STABEN ,  Philip Wilson HOWARD ,  Luke MASTERSON

IPC: A61K47/48 ,  C07K16/30 ,  A61K31/5517 ,  C07K16/28

Abstract: This invention relates to peptidomimetic linkers and anti-body drug conjugates thereof, pharmaceutical compositions containing them, and to their use in therapy for the prevention treatment of cancer.

Abstract translation: 本发明涉及肽模拟接头及其抗体药物偶联物，含有它们的药物组合物及其在预防癌症治疗中的用途。