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公开(公告)号:US20100274005A1
公开(公告)日:2010-10-28
申请号:US12833752
申请日:2010-07-09
申请人: Brett D. Allison , Laurent Gomez , Cheryl A. Grice , Michael D. Hack , Brian J. Morrow , S. Timothy Motley , Alejandro Santillan, JR. , Karen J. Shaw , Kimberly L. Schwarz , Liu Y. Tang , Hariharan Venkatesan , John J. M. Wiener
发明人: Brett D. Allison , Laurent Gomez , Cheryl A. Grice , Michael D. Hack , Brian J. Morrow , S. Timothy Motley , Alejandro Santillan, JR. , Karen J. Shaw , Kimberly L. Schwarz , Liu Y. Tang , Hariharan Venkatesan , John J. M. Wiener
IPC分类号: C07D487/04 , C07D471/04 , C07D417/14 , C07D403/14 , C07D498/04
CPC分类号: A61K31/4375 , A61K31/444 , A61K31/4453 , A61K31/4709 , A61K31/498 , A61K31/538 , A61K31/5383 , A61K31/5415 , A61K31/55 , C07D401/04 , C07D401/14 , C07D405/14 , C07D409/14 , C07D417/12 , C07D417/14 , C07D471/04
摘要: Antibacterial compounds, compositions containing them, and methods of use for the inhibition of bacterial activity and the treatment, prevention or inhibition of bacterial infection.
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公开(公告)号:US20160039790A1
公开(公告)日:2016-02-11
申请号:US14777492
申请日:2014-03-13
申请人: Wenying CHAI , Curt A. DVORAK , Wendy ECCLES , James P. EDWARDS , Steven D. GOLDBERG , Paul J. KRAWCZUK , Alec D. LEBSACK , Jing LIU , Daniel J. PIPPEL , Zachary S. SALES , Virginia M. TANIS , Mark S. TICHENOR , John J.M. WIENER , JANSSEN PHARMACEUTICA NV
发明人: Wenying Chai , Curt A. Dvorak , Wendy Eccles , James P. Edwards , Steven D. Goldberg , Paul J. Krawczuk , Alec D. Lebsack , Jing Liu , Daniel J. Pippel , Zachary S. Sales , Virginia M. Tanis , Mark S. Tichenor , John J. M. Wiener
IPC分类号: C07D401/12 , C07D401/14 , C07D403/14 , C07D403/12
CPC分类号: C07D401/12 , A61K31/4184 , A61K31/4439 , A61K31/454 , A61K31/4545 , A61K31/506 , C07D401/14 , C07D403/12 , C07D403/14
摘要: The present invention relates to compounds of Formula (I), and solvates, hydrates, and pharmaceutically acceptable salts thereof, wherein X1, X1′, X1″, R1, R2 and R3 are as defined herein, useful as FLAP modulators. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I). Methods of making and using the compounds of Formula (I) are also within the scope of the invention.
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