Method and apparatus for minimizing spectral interference due to within and between sample variations during in-situ spectral sampling of tissue
    11.
    发明授权
    Method and apparatus for minimizing spectral interference due to within and between sample variations during in-situ spectral sampling of tissue 失效
    用于在组织的原位光谱采样期间最小化由于样品变化之内和之间的光谱干扰的方法和装置

    公开(公告)号:US06839584B2

    公开(公告)日:2005-01-04

    申请号:US09954856

    申请日:2001-09-17

    IPC分类号: A61B20060101 A61B5/00

    摘要: An apparatus and method for reproducibly interfacing a living tissue sample to the measurement probe of a spectrometer instrument in-situ minimizes spectral interference related to sampling variations. A minimal contact subject interface includes supports replaceably mounted on a base. An optical coupling means, such as a fiber optic probe, contacts the measurement site through a probe aperture in the base. During use, a subject rests an extremity on the support elements, so that the extremity is reproducibly positioned and supported in relation to the optical coupling means. The supports have a small contact area, minimizing contact with the skin at the measurement site. The interface module is adjustable to fit any subject.By reproducibly positioning and supporting the body appendage using minimal contact supports, spectral interference due to variations in placement, applied pressure, and temperature transients secondary to contact with the interface module are greatly minimized.

    摘要翻译: 将生物组织样本可再现地将光谱仪器的测量探针接地的设备和方法原位最小化与采样变化相关的光谱干扰。 最小接触主体界面包括可替换地安装在基座上的支撑件。 诸如光纤探针的光学耦合装置通过基座中的探针孔接触测量部位。 在使用期间,被摄体将支撑元件的末端置于支撑元件上,使得末端相对于光耦合装置可再现地定位和支撑。 支架具有很小的接触面积,使测量点与皮肤接触最小化。 接口模块是可调整的,适合任何物体。通过使用最小的接触支持可重复地定位和支撑身体附件,由于与接口模块接触的位置变化,施加的压力和温度瞬变引起的频谱干扰大大降低。