Keratin-Binding Polypeptides
    14.
    发明申请
    Keratin-Binding Polypeptides 审中-公开
    角蛋白结合多肽

    公开(公告)号:US20080075684A1

    公开(公告)日:2008-03-27

    申请号:US11597815

    申请日:2005-05-24

    IPC分类号: A61K8/64 C07K14/475

    摘要: The invention relates to novel keratin-binding protein active substances, and also to the production and use thereof. Particularly suitable keratin-binding polypeptides are sequences which are contained in human desmoplakin or are derived therefrom by altering the human desmoplakin polypeptide sequences such as amino acid insertions, substitutions or deletions. The polypeptide sequences of the human desmoplakin is represented in SEQ ID NO: 1. A suitable keratin-binding domain (domain B) is the polypeptide sequence SEQ ID NO: 1, position 2193 2481, in addition to functional equivalents thereof. An additional keratin-binding domain (domain C) is the polypeptide sequence SEQ ID NO: 1, position 2606 2871 and the functional equivalents thereof.

    摘要翻译: 本发明涉及新型角蛋白结合蛋白活性物质,以及其生产和使用。 特别合适的角蛋白结合多肽是通过改变人类粘蛋白多肽序列例如氨基酸插入,取代或缺失而包含在人类丝氨酸蛋白酶中或通过其衍生的序列。 人类粘蛋白的多肽序列表示在SEQ ID NO:1中。合适的角蛋白结合结构域(结构域B)是除了其功能等同物之外的多肽序列SEQ ID NO:1,位置21932481。 另外的角蛋白结合结构域(结构域C)是多肽序列SEQ ID NO:1,位置2606 2871及其功能等同物。

    Use of Hydrophobin-Polypeptides and Conjugates From Hydrophobin-Polypeptides Having Active and Effect Agents and the Production Thereof and Use Thereof In the Cosmetic Industry
    17.
    发明申请
    Use of Hydrophobin-Polypeptides and Conjugates From Hydrophobin-Polypeptides Having Active and Effect Agents and the Production Thereof and Use Thereof In the Cosmetic Industry 审中-公开
    化妆品行业使用具有活性和有效成分及其制备及其用途的疏水双歧杆菌和缀合物

    公开(公告)号:US20090136433A1

    公开(公告)日:2009-05-28

    申请号:US11922650

    申请日:2006-06-23

    摘要: Cosmetic composition for the treatment of keratin-containing materials, mucosa and teeth, comprising at least one hydrophobin polypeptide sequence (i) (I) Xn-C1-X1-50-C2-X0-5-C3-Xp-C4-X1-100-C5-X1-50-C6- X0-5-C7-X1-50-C8-Xm

    摘要翻译: 用于治疗含角蛋白的材料,粘膜和牙齿的化妆品组合物,其包含至少一种疏水蛋白多肽序列(i)

    (I) > Xn-C1-X1-50-C2-X0- 5-C3-Xp-C4-X1-100-C5-X1-50-C6 - 条目> X0-5-C7-X1-50-C8-Xm

      Poly(ADP-ribose) polymerase-gene
      19.
      发明授权
      Poly(ADP-ribose) polymerase-gene 失效
      聚(ADP-核糖)聚合酶基因

      公开(公告)号:US07754459B1

      公开(公告)日:2010-07-13

      申请号:US09701586

      申请日:1999-06-04

      IPC分类号: C12N9/12

      摘要: The invention relates to poly(ADP-ribose)polymerase (PARP) homologs which have an amino acid sequence which has a) a functional NAD+ binding domain and b) no zinc finger sequence motif of the general formula CX2CXmHX2C  in which  m is an integral value from 28 or 30, and the X radicals are, independently of one another, any amino acid; and the functional equivalents thereof; nucleic acids coding therefor; antibodies with specificity for the novel protein; pharmaceutical and gene therapy compositions which comprise products according to the invention; methods for the analytical determination of the proteins and nucleic acids according to the invention; methods for identifying effectors or binding partners of the proteins according to the invention; novel PARP effectors; and methods for determining the activity of such effectors.

      摘要翻译: 本发明涉及具有氨基酸序列的聚(ADP-核糖)聚合酶(PARP)同系物,该氨基酸序列具有a)功能性的NAD +结合域,b)没有通式CX2CXmHX2C的锌指序列基序,其中m是整数值 28或30个,X基彼此独立地为任何氨基酸; 及其功能等同物; 为此编码的核酸; 对新蛋白具有特异性的抗体; 包括根据本发明的产品的药物和基因治疗组合物; 根据本发明的用于分析测定蛋白质和核酸的方法; 用于鉴定根据本发明的蛋白质的效应物或结合配偶体的方法; 新型PARP效应器; 以及用于确定这种效应物的活性的方法。

      Method for manufacturing paper, cardboard and paperboard using endo-beta-1,4-glucanases as dewatering means
      20.
      发明授权
      Method for manufacturing paper, cardboard and paperboard using endo-beta-1,4-glucanases as dewatering means 有权
      使用内β-1,4-葡聚糖酶作为脱水装置制造纸,纸板和纸板的方法

      公开(公告)号:US08394237B2

      公开(公告)日:2013-03-12

      申请号:US13058874

      申请日:2009-08-28

      IPC分类号: D21H11/00

      摘要: A process for the production of paper, board and cardboard by draining a paper stock on a wire in the presence of at least one cationic polymeric retention aid and/or retention aid system with sheet formation and drying of the sheets, wherein an endo-β-1,4-glucanase is metered in an amount of from 0.00001 to 0.01% by weight, based on the dry paper stock, into the paper stock before the addition of the at least one cationic polymeric retention aid and/or retention aid system.

      摘要翻译: 一种用于在存在至少一种阳离子聚合物助留剂和/或助留剂系统的情况下通过在钢丝上排出纸料以生产纸,纸板和纸板的方法,所述阳离子聚合物助留剂和/或助留剂体系具有片材的形成和干燥,其中内含物 ;在加入至少一种阳离子聚合物助留剂和/或助留剂体系之前,将-1,4-葡聚糖酶以基于干纸原料的0.00001至0.01重量%的量计量加入纸料中 。