公开(公告)号：US06689904B2

公开(公告)日：2004-02-10

申请号：US10185445

申请日：2002-06-27

申请人： Alexander Alexei Greenfield ,  John Anthony Butera

发明人： Alexander Alexei Greenfield ,  John Anthony Butera

IPC分类号： C07C6112

CPC分类号： C07D493/08 ,  C07C229/50 ,  C07C2603/64

摘要： This invention provides processes for preparing a group of novel bridged tricyclic compounds having the formula: wherein X is (CH2)n, O, S, SO, SO2 or CR1R2; n is 1 or 2; and R1 and R2 are, independently, hydrogen, halogen, hydroxy, alkyl of one to six carbon atoms, alkoxy of one to six carbon atoms, or R1 and R2, taken together with the carbon to which they are attached, form cycloalkyl of three to six carbon atoms, an alkylidene of up to six carbon atoms or a carbonyl.

摘要翻译： 本发明提供了制备一组具有下式的新型桥连三环化合物的方法：其中X是（CH 2）n，O，S，SO，SO 2或CR 1 R 2; n为1或2; R 1和R 2独立地是氢，卤素，羟基，1至6个碳原子的烷基，1至6个碳原子的烷氧基或R 1和R 2与 它们所连接的碳形成3至6个碳原子的环烷基，最多6个碳原子的亚烷基或羰基。