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公开(公告)号:US08772297B2
公开(公告)日:2014-07-08
申请号:US13579843
申请日:2011-02-17
申请人: Hideaki Kakeya , Akira Hattori , Yasuaki Takasu , Nobutaka Fujii , Shinya Oishi , Soichi Kojima , Mitsuko Hara
发明人: Hideaki Kakeya , Akira Hattori , Yasuaki Takasu , Nobutaka Fujii , Shinya Oishi , Soichi Kojima , Mitsuko Hara
IPC分类号: A61K31/495 , C07D295/104
CPC分类号: C07D295/104 , C07D211/28 , C07D295/18 , C07D405/12
摘要: The present invention provides a compound represented by the following formula (I) or a physiologically acceptable salt thereof, and use thereof for the prophylaxis or treatment of TGF-β-related diseases: wherein Y is a hydrogen atom and the like; R2 is and the like; R3 is —NR8—R9— and the like; R4, R5, R6 and R7 are the same or different and each is a hydrogen atom and the like; and X is and the like.
摘要翻译: 本发明提供由下式(I)表示的化合物或其生理学上可接受的盐,及其用于预防或治疗TGF-β相关疾病的用途:其中Y为氢原子等; R2是等等; R3是-NR8-R9-等; R4,R5,R6和R7相同或不同,各自为氢原子等; X等。