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公开(公告)号:US09102614B2
公开(公告)日:2015-08-11
申请号:US13806067
申请日:2011-07-01
申请人: Kerim Babaoglu , Elizabeth Bacon , Kyla Bjornson , Hongyan Guo , Randall L. Halcomb , Paul Hrvatin , John O. Link , Hongtao Liu , Ryan Mcfadden , Michael L. Mitchell , Paul Roethle , James Taylor , James D. Trenkle , Randall W. Vivian , Lianhong Xu
发明人: Kerim Babaoglu , Elizabeth Bacon , Kyla Bjornson , Hongyan Guo , Randall L. Halcomb , Paul Hrvatin , John O. Link , Hongtao Liu , Ryan Mcfadden , Michael L. Mitchell , Paul Roethle , James Taylor , James D. Trenkle , Randall W. Vivian , Lianhong Xu
IPC分类号: C07D295/073 , C07D295/155 , C07D493/04 , C07D311/20 , C07D311/58 , C07D239/34 , C07D239/36 , C07D231/12 , C07D213/64 , C07D213/73 , C07D213/65 , C07D205/04 , C07D215/14 , C07C59/64 , C07D211/48 , C07D215/04 , C07D233/58 , C07D241/12 , C07D309/10 , C07D491/06 , C07C229/34 , C07C233/47 , C07C255/57 , C07C271/22 , C07C311/16 , C07D239/26 , C07D239/42 , C07D487/04
CPC分类号: C07C59/64 , C07C229/34 , C07C233/47 , C07C255/57 , C07C271/22 , C07C311/16 , C07D205/04 , C07D211/48 , C07D213/64 , C07D213/65 , C07D213/73 , C07D215/04 , C07D215/14 , C07D231/12 , C07D233/58 , C07D239/26 , C07D239/34 , C07D239/36 , C07D239/42 , C07D241/12 , C07D295/073 , C07D295/155 , C07D309/10 , C07D311/20 , C07D311/58 , C07D487/04 , C07D491/06 , C07D493/04
摘要: The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I, processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds of formula (I).
摘要翻译: 本发明提供了本文所述的式(I)化合物或其盐。 本发明还提供了包含式I化合物的药物组合物,制备式(I)化合物的方法,用于制备式I化合物的中间体和治疗HIV病毒增殖的治疗方法,治疗AIDS或延迟 使用式(I)化合物的哺乳动物中的AIDS或ARC症状。
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公开(公告)号:US20130210801A1
公开(公告)日:2013-08-15
申请号:US13806048
申请日:2011-07-01
申请人: Kerim Babaoglu , Kyla Bjornson , Hongyan Guo , Randall L. Halcomb , John O. Link , Hongtao Liu , Michael L. Mitchell , Jianyu Sun , James Taylor , Randall W. Vivian , Lianhong Xu
发明人: Kerim Babaoglu , Kyla Bjornson , Hongyan Guo , Randall L. Halcomb , John O. Link , Hongtao Liu , Michael L. Mitchell , Jianyu Sun , James Taylor , Randall W. Vivian , Lianhong Xu
IPC分类号: C07D498/04 , C07D215/48 , C07D491/052 , C07D215/14
CPC分类号: C07D498/04 , C07D215/06 , C07D215/14 , C07D215/18 , C07D215/20 , C07D215/227 , C07D215/38 , C07D215/48 , C07D401/04 , C07D401/12 , C07D405/04 , C07D413/04 , C07D417/04 , C07D487/04 , C07D491/052 , C07D519/00
摘要: The invention provides compounds of formula (I): or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula I and therapeutic methods for treating the proliferation of the HIV virus, treating AIDS or delaying the onset of AIDS or ARC symptoms in a mammal using compounds of formula (I).
摘要翻译: 本发明提供了本文所述的式(I)化合物或其盐。 本发明还提供包含式(I)化合物的药物组合物,制备式(I)化合物的方法,用于制备式I化合物的中间体和治疗HIV病毒增殖的治疗方法,治疗AIDS或延迟 使用式(I)化合物在哺乳动物中发生AIDS或ARC症状。
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公开(公告)号:US08669234B2
公开(公告)日:2014-03-11
申请号:US13491446
申请日:2012-06-07
申请人: Hongyan Guo , Darryl Kato , Thorsten A. Kirschberg , Evan S. Krygowski , John O. Link , Michael L. Mitchell , Jay P. Parrish , James Taylor
发明人: Hongyan Guo , Darryl Kato , Thorsten A. Kirschberg , Evan S. Krygowski , John O. Link , Michael L. Mitchell , Jay P. Parrish , James Taylor
IPC分类号: C07D401/14 , C07D403/04 , C07D403/14 , C07D409/14 , C07D413/04 , C07D417/04 , C07D417/14 , C07D495/04 , A61P1/16 , A61P31/14 , A61K31/4178 , A61K31/7068 , A61K31/7052 , A61K31/4184 , A61K31/7056
CPC分类号: C07D403/14 , A61K31/4025 , A61K31/4178 , A61K31/4184 , A61K31/427 , A61K31/435 , A61K31/437 , A61K31/4439 , A61K31/454 , A61K31/496 , A61K31/519 , A61K31/5377 , A61K31/5415 , A61K31/55 , A61K45/06 , A61P31/12 , C07D207/16 , C07D401/14 , C07D403/04 , C07D405/14 , C07D409/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D471/08 , C07D471/10 , C07D487/04 , C07D491/113 , C07D495/04 , C07F5/025
摘要: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号:US09156823B2
公开(公告)日:2015-10-13
申请号:US13884578
申请日:2011-11-16
申请人: Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Viet Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
发明人: Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Viet Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
IPC分类号: C07D403/14 , A61K31/4184 , C07D491/113 , A61K31/5377 , C07D491/107 , A61K31/4188 , A61K31/4178 , A61K45/06 , C07D405/14 , C07D417/14 , C07D471/08 , C07D491/10 , C07D493/04 , C07D495/04 , C07D513/04
CPC分类号: C07D403/14 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/5377 , A61K45/06 , C07D405/14 , C07D417/14 , C07D471/08 , C07D491/10 , C07D491/107 , C07D491/113 , C07D493/04 , C07D495/04 , C07D513/04 , A61K2300/00
摘要: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号:US20140309432A1
公开(公告)日:2014-10-16
申请号:US14261325
申请日:2014-04-24
申请人: Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Viet Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
发明人: Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Viet Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
IPC分类号: C07F5/02 , C07D491/052
CPC分类号: C07D491/052 , A61K31/4188 , A61K31/7056 , A61K31/7064 , A61K31/7072 , A61K38/06 , A61K38/07 , A61K38/21 , A61K45/06 , A61K47/60 , C07D405/12 , C07F5/025 , Y10S514/894 , A61K2300/00
摘要: The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号:US20140018313A1
公开(公告)日:2014-01-16
申请号:US13884578
申请日:2011-11-16
申请人: Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
发明人: Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
IPC分类号: C07D403/14 , C07D491/113 , A61K31/4188 , C07D491/107 , A61K45/06 , A61K31/4184 , A61K31/5377
CPC分类号: C07D403/14 , A61K31/4178 , A61K31/4184 , A61K31/4188 , A61K31/5377 , A61K45/06 , C07D405/14 , C07D417/14 , C07D471/08 , C07D491/10 , C07D491/107 , C07D491/113 , C07D493/04 , C07D495/04 , C07D513/04 , A61K2300/00
摘要: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号:US20140112885A1
公开(公告)日:2014-04-24
申请号:US14049133
申请日:2013-10-08
申请人: Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Viet Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
发明人: Elizabeth M. Bacon , Jeromy J. Cottell , Ashley Anne Katana , Darryl Kato , Evan S. Krygowski , John O. Link , James Taylor , Chinh Viet Tran , Teresa Alejandra Trejo Martin , Zheng-Yu Yang , Sheila Zipfel
IPC分类号: C07D491/052 , A61K31/7056 , A61K38/21 , A61K31/4188 , A61K45/06
CPC分类号: C07D491/052 , A61K31/4188 , A61K31/7056 , A61K31/7064 , A61K31/7072 , A61K38/06 , A61K38/07 , A61K38/21 , A61K45/06 , A61K47/60 , C07D405/12 , C07F5/025 , Y10S514/894 , A61K2300/00
摘要: The disclosure is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
摘要翻译: 本公开涉及抗病毒化合物,含有这些化合物的组合物和包括施用这些化合物的治疗方法以及可用于制备这些化合物的方法和中间体。
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公开(公告)号:US20140051626A1
公开(公告)日:2014-02-20
申请号:US13932945
申请日:2013-07-01
申请人: Jeromy J. Cottell , John O. Link , Scott D. Schroeder , James Taylor , Winston C. Tse , Randall W. Vivian , Zheng-Yu Yang
发明人: Jeromy J. Cottell , John O. Link , Scott D. Schroeder , James Taylor , Winston C. Tse , Randall W. Vivian , Zheng-Yu Yang
IPC分类号: C07K5/083
CPC分类号: C07K5/0808 , A61K38/00 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D495/04 , C07K5/0804 , C07K5/0812 , C07K5/0821
摘要: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号:US08513186B2
公开(公告)日:2013-08-20
申请号:US12215601
申请日:2008-06-26
申请人: Jeromy J. Cottell , John O. Link , Scott D. Schroeder , James Taylor , Winston C. Tse , Randall W. Vivian , Zheng-Yu Yang
发明人: Jeromy J. Cottell , John O. Link , Scott D. Schroeder , James Taylor , Winston C. Tse , Randall W. Vivian , Zheng-Yu Yang
IPC分类号: A61K38/00
CPC分类号: C07K5/0808 , A61K38/00 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D495/04 , C07K5/0804 , C07K5/0812 , C07K5/0821
摘要: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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公开(公告)号:US20090186869A1
公开(公告)日:2009-07-23
申请号:US12215601
申请日:2008-06-26
申请人: Jeromy J. Cottell , John O. Link , Scott D. Schroeder , James Taylor , Winston C. Tse , Randall W. Vivian , Zheng-Yu Yang
发明人: Jeromy J. Cottell , John O. Link , Scott D. Schroeder , James Taylor , Winston C. Tse , Randall W. Vivian , Zheng-Yu Yang
IPC分类号: A61K31/397 , C07D401/14 , A61K31/4709 , A61K31/4725 , A61K31/4365 , C07D471/02 , C07D415/00 , C07D407/14 , C07D401/12 , C07D245/04 , A61K31/506 , C07D413/14 , A61K31/5377
CPC分类号: C07K5/0808 , A61K38/00 , C07D207/16 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D405/14 , C07D413/14 , C07D417/14 , C07D487/04 , C07D495/04 , C07K5/0804 , C07K5/0812 , C07K5/0821
摘要: The invention is related to anti-viral compounds, compositions containing such compounds, and therapeutic methods that include the administration of such compounds, as well as to processes and intermediates useful for preparing such compounds.
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