公开(公告)号：US20190299210A1

公开(公告)日：2019-10-03

申请号：US16443727

申请日：2019-06-17

Applicant: Illumina, Inc. ,  Illumina Singapore Pte. Ltd.

Inventor： Richard L. Lemoine ,  James Osmus ,  Sz-Chin Steven Lin ,  Beng Keong Ang

IPC: B01L3/00 ,  G01N21/75 ,  G01N21/01 ,  F04B19/00

Abstract: A cartridge assembly comprises a housing having an illumination chamber and a well plate. The well plate is maintained within the housing and has liquid wells to receive desired amounts of liquids. The well plate includes a fluidics analysis station aligned with the illumination chamber, and an interface window and interface ports located at the fluidics analysis station. The well plate includes a valve station and pump station. A piercer unit is provided in the housing and positioned proximate to the wells. The piercer unit includes a piercer element and is to be moved to a piercing position where the piercer element pierces a cover for the corresponding well. A pump assembly on the well plate at the pump station manages fluid flow through the channels between the pump station and the fluidics analysis station. The housing includes a flow cell chamber to receive a removable flow cell cartridge.