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公开(公告)号：US20080016591A1
公开(公告)日：2008-01-17
申请号：US11776423
申请日：2007-07-11
申请人： Alison Eenennaam , Henry Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
发明人： Alison Eenennaam , Henry Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
CPC分类号： C12N9/1007 , C12N15/8243
摘要： The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methyltransferase activity. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express the aforementioned polypeptides. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway.
摘要翻译： 本发明涉及与生育酚生物合成途径相关的基因。 更具体地，本发明提供并包括与编码具有甲基转移酶活性的多肽的基因相关的核酸分子，蛋白质和抗体。 本发明还提供了利用这些试剂的方法，例如在基因分离，基因分析和转基因植物的生产中。 此外，本发明包括被修饰以表达上述多肽的转基因植物。 此外，本发明包括从生育酚生物合成途径生产产物的方法。
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12.发明申请Genes encoding 4-Hydroxyphenylpyruvate dioxygenase (HPPD) enzymes for plant metabolic engineering 有权编码用于植物代谢工程的4-羟基苯丙酮酸双加氧酶（HPPD）酶的基因公开(公告)号：US20050289664A1
公开(公告)日：2005-12-29
申请号：US11043542
申请日：2005-01-26
申请人： Farhad Moshiri , Ming Hao , Balasulojini Karunanandaa , Henry Valentin , Tyamagondlu Venkatesh , Yun-Hua Huang Wong
发明人： Farhad Moshiri , Ming Hao , Balasulojini Karunanandaa , Henry Valentin , Tyamagondlu Venkatesh , Yun-Hua Huang Wong
CPC分类号： C12N9/0069 , C12N15/8243 , C12N15/8273
摘要： The present invention is in the field of plant genetics and biochemistry. More specifically, the present invention relates to genes and polypeptides associated with the tocopherol biosynthesis pathway, namely those encoding 4-Hydroxyphenylpyruvate Dioxygenase activity, and uses thereof.
摘要翻译： 本发明在植物遗传学和生物化学领域。 更具体地，本发明涉及与生育酚生物合成途径相关的基因和多肽，即编码4-羟基苯丙酮酸双加氧酶活性的基因和多肽及其用途。
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公开(公告)号：US07906710B2
公开(公告)日：2011-03-15
申请号：US12477673
申请日：2009-06-03
申请人： Balasulojini Karunanandaa , Martha Post-Beittenmiller , Mylavarapu Venkatramesh , Ganesh M. Kishore , Gregory M. Thorne , John R. LeDeaux
发明人： Balasulojini Karunanandaa , Martha Post-Beittenmiller , Mylavarapu Venkatramesh , Ganesh M. Kishore , Gregory M. Thorne , John R. LeDeaux
CPC分类号： C12N9/0073 , C12N9/0006 , C12N9/0083 , C12N9/1007 , C12N15/8243 , C12N15/8247 , C12Y101/01034 , C12Y114/99007
摘要： Disclosed are constructs comprising sequences encoding 3-hydroxy-3methylglutaryl-Coenzyme A reductase and at least one other sterol synthesis pathway enzyme. Also disclosed are methods for using such constructs to alter sterol production and content in cells, plants, seeds and storage organs of plants. Also provided are oils and compositions containing altered sterol levels produced by use of the disclosed constructs. Novel nucleotide sequences useful in the alteration of sterol production are also provided. Also provided are cells, plants, seeds and storage organs of plants comprising sequences encoding 3-hydroxy-3methylglutaryl-Coenzyme A reductase, at least one other sterol synthesis pathway enzyme and at least one tocopherol synthesis enzyme.
摘要翻译： 公开了包含编码3-羟基-3甲基戊二酰辅酶A还原酶和至少一种其它甾醇合成途径酶的序列的构建体。 还公开了使用这种构建体来改变植物的细胞，植物，种子和储存器官中的固醇产生和含量的方法。 还提供了含有通过使用所公开的构建体产生的改变的固醇水平的油和组合物。 还提供了可用于改变甾醇生产的新型核苷酸序列。 还提供了包含编码3-羟基-3甲基戊二酰辅酶A还原酶，至少一种其它甾醇合成途径酶和至少一种生育酚合成酶的序列的植物的细胞，植物，种子和储存器官。
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公开(公告)号：US20100037354A1
公开(公告)日：2010-02-11
申请号：US12477673
申请日：2009-06-03
申请人： Balasulojini Karunanandaa , Martha Post-Beittenmiller , Mylavarapu Venkatramesh , Ganesh M. Kishore , Gregory M. Thorne , John R. LeDeaux
发明人： Balasulojini Karunanandaa , Martha Post-Beittenmiller , Mylavarapu Venkatramesh , Ganesh M. Kishore , Gregory M. Thorne , John R. LeDeaux
CPC分类号： C12N9/0073 , C12N9/0006 , C12N9/0083 , C12N9/1007 , C12N15/8243 , C12N15/8247 , C12Y101/01034 , C12Y114/99007
摘要： Disclosed are constructs comprising sequences encoding 3-hydroxy-3methylglutaryl-Coenzyme A reductase and at least one other sterol synthesis pathway enzyme. Also disclosed are methods for using such constructs to alter sterol production and content in cells, plants, seeds and storage organs of plants. Also provided are oils and compositions containing altered sterol levels produced by use of the disclosed constructs. Novel nucleotide sequences useful in the alteration of sterol production are also provided. Also provided are cells, plants, seeds and storage organs of plants comprising sequences encoding 3-hydroxy-3methylglutaryl-Coenzyme A reductase, at least one other sterol synthesis pathway enzyme and at least one tocopherol synthesis enzyme.
摘要翻译： 公开了包含编码3-羟基-3甲基戊二酰辅酶A还原酶和至少一种其它甾醇合成途径酶的序列的构建体。 还公开了使用这种构建体来改变植物的细胞，植物，种子和储存器官中的固醇产生和含量的方法。 还提供了含有通过使用所公开的构建体产生的改变的固醇水平的油和组合物。 还提供了可用于改变甾醇生产的新型核苷酸序列。 还提供了包含编码3-羟基-3甲基戊二酰辅酶A还原酶，至少一种其它甾醇合成途径酶和至少一种生育酚合成酶的序列的植物的细胞，植物，种子和储存器官。
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公开(公告)号：US07244877B2
公开(公告)日：2007-07-17
申请号：US10219810
申请日：2002-08-16
申请人： Alison Van Eenennaam , Henry E. Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
发明人： Alison Van Eenennaam , Henry E. Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
CPC分类号： C12N9/1007 , C12N15/8243
摘要： The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methyltransferase activity. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express the aforementioned polypeptides. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway.
摘要翻译： 本发明涉及与生育酚生物合成途径相关的基因。 更具体地，本发明提供并包括与编码具有甲基转移酶活性的多肽的基因相关的核酸分子，蛋白质和抗体。 本发明还提供了利用这些试剂的方法，例如在基因分离，基因分析和转基因植物的生产中。 此外，本发明包括被修饰以表达上述多肽的转基因植物。 此外，本发明包括从生育酚生物合成途径生产产物的方法。
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16.发明授权Nucleic acid molecule and encoded protein associated with sterol synthesis and metabolism 有权核酸分子和与甾醇合成和代谢相关的编码蛋白公开(公告)号：US06723837B1
公开(公告)日：2004-04-20
申请号：US09614221
申请日：2000-07-11
IPC分类号： C12N1509
CPC分类号： C12N15/8243 , C07K14/415
摘要： This invention relates to the field of biotechnology, particularly as it pertains to a nucleic acid molecule encoding a protein associated with sterol and phytosterol synthesis and metabolism. The invention also relates to methods of detection using the nucleic acid molecule, or the encoded protein as a probe or in a microarray.
摘要翻译： 本发明涉及生物技术领域，特别是涉及编码与甾醇和植物甾醇合成和代谢相关的蛋白质的核酸分子。 本发明还涉及使用核酸分子或编码的蛋白质作为探针或微阵列进行检测的方法。
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公开(公告)号：US20120005773A1
公开(公告)日：2012-01-05
申请号：US12998243
申请日：2009-09-30
申请人： Eric D. Aasen , Mark Scott Abad , Edwards Allen , Thandoni Rao Ambika , Veena S. Anil , Alice Clara Augustine , Stephanie L. Back , Pranesh Badami , Amarjit Basra , Kraig L. Brustad , Molian Deng , Todd Dezwaan , Charles Dietrich , Stephen M. Duff , Karen K. Gabbert , Steve He , Bill L. Hendrix , Hongwu Jia , Vidya Kammaradi Ramanath Bhat , Hongwu Jia , Vidya Kammaradi Ramanath Bhat , Balasulojini Karunanandaa , Kevin R. Kosola , Kempagangaiah Krishnamurthy , Ganesh Kumar , Saritha V. Kuriakose , Shantala Lakkanna , Mark E. Leibman , Linda Lutfiyya , Savitha Madappa , Sivalinganna Manjunath , Robert J. Meister , Bellur Narasimba Prasad , Sasha Preuss , Qungang Qi , Dhanalakshmi Ramachandra , S. Sangeetha , Scott Saracco , Chitresh Sharma , Vijay K. Sharma , Rajani Monnanda Somaiah , Padmini Sudarshana , Rebecca L. Thompson-Mize , Srikanth Venkatachalayya , Tyamagondlu V. Venkatesh , Huai Wang , Jingrui Wu , Xiaoyun Wu , Xiaofeng Sean Yang , Qin Zeng , Jianmin Zhao
发明人： Eric D. Aasen , Mark Scott Abad , Edwards Allen , Thandoni Rao Ambika , Veena S. Anil , Alice Clara Augustine , Stephanie L. Back , Pranesh Badami , Amarjit Basra , Kraig L. Brustad , Molian Deng , Todd Dezwaan , Charles Dietrich , Stephen M. Duff , Karen K. Gabbert , Steve He , Bill L. Hendrix , Hongwu Jia , Vidya Kammaradi Ramanath Bhat , Hongwu Jia , Vidya Kammaradi Ramanath Bhat , Balasulojini Karunanandaa , Kevin R. Kosola , Kempagangaiah Krishnamurthy , Ganesh Kumar , Saritha V. Kuriakose , Shantala Lakkanna , Mark E. Leibman , Linda Lutfiyya , Savitha Madappa , Sivalinganna Manjunath , Robert J. Meister , Bellur Narasimba Prasad , Sasha Preuss , Qungang Qi , Dhanalakshmi Ramachandra , S. Sangeetha , Scott Saracco , Chitresh Sharma , Vijay K. Sharma , Rajani Monnanda Somaiah , Padmini Sudarshana , Rebecca L. Thompson-Mize , Srikanth Venkatachalayya , Tyamagondlu V. Venkatesh , Huai Wang , Jingrui Wu , Xiaoyun Wu , Xiaofeng Sean Yang , Qin Zeng , Jianmin Zhao
CPC分类号： C12N15/8251 , C12N15/8247 , C12N15/8261 , C12N15/8273 , C12N15/8274 , C12N15/8275 , Y02A40/146
摘要： This invention provides transgenic plant cells with recombinant DNA for expression of proteins that are useful for imparting enhanced agronomic trait(s) to transgenic crop plants. This invention also provides transgenic plants and progeny seed comprising the transgenic plant cells where the plants are selected for having an enhanced trait selected from the group of traits consisting of enhanced water use efficiency, enhanced cold tolerance, increased yield, enhanced nitrogen use efficiency, enhanced seed protein and enhanced seed oil. Also disclosed are methods for manufacturing transgenic seed and plants with enhanced trait.
摘要翻译： 本发明提供具有用于表达蛋白质的重组DNA的转基因植物细胞，其可用于赋予转基因作物植物增强的农艺性状。 本发明还提供包含转基因植物细胞的转基因植物和后代种子，其中植物被选择用于具有增强的性状，所述性状选自由增强的水利用效率，增强的耐冷性，增加的产量，增强的氮利用效率，增强的氮利用效率， 种子蛋白和增强种子油。 还公开了用于制备具有增强特征的转基因种子和植物的方法。
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公开(公告)号：US07605244B2
公开(公告)日：2009-10-20
申请号：US11776441
申请日：2007-07-11
申请人： Alison Van Eenennaam , Henry E. Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
发明人： Alison Van Eenennaam , Henry E. Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
CPC分类号： C12N9/1007 , C12N15/8243
摘要： The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methyltransferase activity. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express the aforementioned polypeptides. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway.
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公开(公告)号：US20080016592A1
公开(公告)日：2008-01-17
申请号：US11776429
申请日：2007-07-11
申请人： Alison Eenennaam , Henry Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
发明人： Alison Eenennaam , Henry Valentin , Balasulojini Karunanandaa , Ming Hao , Eric Aasen , Charlene Levering
CPC分类号： C12N9/1007 , C12N15/8243
摘要： The present invention relates to genes associated with the tocopherol biosynthesis pathway. More particularly, the present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with genes that encode polypeptides that have methyltransferase activity. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express the aforementioned polypeptides. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway.
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公开(公告)号：US07238855B2
公开(公告)日：2007-07-03
申请号：US10137310
申请日：2002-05-03
CPC分类号： C12N9/001 , C07K14/47 , C12N9/90 , C12N15/8243
摘要： The present invention is in the field of plant genetics and biochemistry. More specifically, the invention relates to genes associated with the tocopherol biosynthesis pathway. The present invention provides and includes nucleic acid molecules, proteins, and antibodies associated with the genes of the tocopherol biosynthesis pathway. The present invention also provides methods for utilizing such agents, for example in gene isolation, gene analysis and the production of transgenic plants. Moreover, the present invention includes transgenic plants modified to express proteins associated with the tocopherol pathway. In addition, the present invention includes methods for the production of products from the tocopherol biosynthesis pathway.
摘要翻译： 本发明在植物遗传学和生物化学领域。 更具体地，本发明涉及与生育酚生物合成途径相关的基因。 本发明提供并包括与生育酚生物合成途径的基因相关的核酸分子，蛋白质和抗体。 本发明还提供了利用这些试剂的方法，例如在基因分离，基因分析和转基因植物的生产中。 此外，本发明包括被修饰以表达与生育酚途径相关的蛋白质的转基因植物。 此外，本发明包括从生育酚生物合成途径生产产物的方法。
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