公开(公告)号：US07999944B2

公开(公告)日：2011-08-16

申请号：US12256852

申请日：2008-10-23

申请人： Stephen J. Caracci ,  Michael J. Dailey, Jr. ,  William J. Miller ,  Robert A. Modavis ,  Deepti J. Mudaliar ,  David A. Pastel ,  Michael B. Webb ,  Qi Wu

发明人： Stephen J. Caracci ,  Michael J. Dailey, Jr. ,  William J. Miller ,  Robert A. Modavis ,  Deepti J. Mudaliar ,  David A. Pastel ,  Michael B. Webb ,  Qi Wu

IPC分类号： G01N21/55

CPC分类号： G01N21/253 ,  G01N21/39 ,  G01N21/45

摘要： A multi-channel swept wavelength optical interrogation system and a method are described herein that enable the interrogation of one or more biosensors which for example could be located within the wells of a microplate. In one embodiment, the optical interrogation system comprises: (a) a tunable laser that emits an optical beam which has a predetermined sequence of distinct wavelengths over a predetermined time period; (b) a distribution unit that splits the optical beam into a plurality of interrogation beams; (c) an array of optical interrogation units that receive and direct the interrogation beams towards an array of biosensors; (d) the array of optical interrogation units receive a plurality of reflected interrogation beams from the array of biosensors; (e) a data processing device that receives and processes information associated with the reflected interrogation beams to determine for example whether or not there was a biochemical interaction on anyone of the biosensors.

摘要翻译： 本文描述了多通道扫频波长光询问系统和方法，其能够询问一个或多个生物传感器，例如其可位于微板的孔内。 在一个实施例中，光学询问系统包括：（a）可调激光器，其在预定时间段内发射具有预定的不同波长序列的光束; （b）分配单元，其将光束分成多个询问光束; （c）光学询问单元的阵列，其接收并将询问光束定向到生物传感器的阵列; （d）光学询问单元的阵列从生物传感器阵列接收多个反射询问光束; （e）数据处理装置，其接收和处理与所反映的询问光束相关联的信息，以确定例如生物传感器中任何一个生化交互是否存在。

公开(公告)号：US07741598B2

公开(公告)日：2010-06-22

申请号：US12402901

申请日：2009-03-12

申请人： Robert A. Modavis ,  Qi Wu ,  Stephen J. Caracci ,  David A. Pastel

发明人： Robert A. Modavis ,  Qi Wu ,  Stephen J. Caracci ,  David A. Pastel

IPC分类号： G01J1/04 ,  G01J1/58

CPC分类号： G01N21/253 ,  G01N21/39 ,  G01N21/7743 ,  G01N2021/4742 ,  G01N2201/08

摘要： An optical interrogation system and a method are described herein that enable the interrogation of one or more biosensors which can be located within the wells of a microplate. In one embodiment, the optical interrogation system has a tunable laser, N-fiber launches, N-lenses and N-detectors that are set-up to interrogate N-biosensors. In another embodiment, the optical interrogation system has a tunable laser, N-fiber launches, N+1 lenses and N-detectors that are set-up to interrogate N-biosensors.

摘要翻译： 本文描述了光学询问系统和方法，其能够询问可以位于微板的孔内的一个或多个生物传感器。 在一个实施例中，光学询问系统具有可调谐激光器，N-纤维发射，N型透镜和N个检测器，其被设置成询问N-生物传感器。 在另一个实施例中，光学询问系统具有可调激光器，N-光纤发射，N + 1透镜和N个检测器，其被设置成询问N-生物传感器。

公开(公告)号：US20100129856A1

公开(公告)日：2010-05-27

申请号：US12624062

申请日：2009-11-23

申请人： Ye Fang ,  Vasiliy Nikolaevich Goral ,  Joydeep Lahiri ,  Deepti Jayaraman Mudaliar ,  Elizabeth Tran ,  Qi Wu

发明人： Ye Fang ,  Vasiliy Nikolaevich Goral ,  Joydeep Lahiri ,  Deepti Jayaraman Mudaliar ,  Elizabeth Tran ,  Qi Wu

IPC分类号： C12Q1/02 ,  C12M1/34

CPC分类号： G01N15/06 ,  G01N21/553 ,  G01N21/774 ,  G01N2015/0693

摘要： The disclosure provides a device for measuring cellular responses under controlled environments. The disclosure also provides an array of devices for measuring cellular responses under controlled environments. The disclosure also provides methods to study cell signaling using the devices. By using microfluidics, the disclosure enables study of cell signaling under well-defined environment conditions. Such capability can be used for differentiating long-acting ligands from short-acting ligands, for determining the kinetics of receptor resensitization and functional recovery of receptor signaling, and for differentiating the sensitivity of a cell type to laminar flow-induced stress force. Through combination with conventional static label-free cell assays, the full spectrum of a drug compound can be studied in details, thus creating a complete representation of its pharmacology acting on living cells.

摘要翻译： 本公开提供了一种用于在受控环境下测量细胞反应的装置。 本公开还提供了用于在受控环境下测量细胞反应的装置阵列。 本公开还提供了使用该装置研究细胞信号传导的方法。 通过使用微流体，本公开使得能够在明确的环境条件下研究细胞信号。 这种能力可以用于区分长效配体的长效配体，用于确定受体复苏的功能恢复和受体信号的功能恢复的动力学，以及区分细胞类型对层流引起的应力的敏感性。 通过与常规静态无标记细胞测定法的组合，可以详细研究药物化合物的全谱，从而创建其作用于活细胞的药理学的完整表示。

公开(公告)号：US20100014781A1

公开(公告)日：2010-01-21

申请号：US12351187

申请日：2009-01-09

申请人： Kai-Che Liu ,  Fu-Chiang Jan ,  Wen-Chao Chen ,  Cheng-Feng Wu ,  Tsu-Han Chen ,  Qi Wu

发明人： Kai-Che Liu ,  Fu-Chiang Jan ,  Wen-Chao Chen ,  Cheng-Feng Wu ,  Tsu-Han Chen ,  Qi Wu

IPC分类号： G06T15/00 ,  G06F17/30

CPC分类号： H04N13/261 ,  H04N13/128 ,  H04N2213/003

摘要： An example-based 2D to 3D image conversion method, a computer readable medium therefor, and a system are provided. The embodiments are based on an image database with depth information or with which depth information can be generated. With respect to a 2D image to be converted into 3D content, a matched background image is found from the database. In addition, graph-based segmentation and comparison techniques are employed to detect the foreground of the 2D image so that the relative depth map can be generated from the foreground and background information. Therefore, the 3D content can be provided with the 2D image plus the depth information. Thus, users can rapidly obtain the 3D content from the 2D image automatically and the rendering of the 3D content can be achieved.

摘要翻译： 提供了一种基于示例的2D到3D图像转换方法，其计算机可读介质和系统。 实施例基于具有深度信息的图像数据库或可以生成哪个深度信息。 对于要转换为3D内容的2D图像，从数据库中找到匹配的背景图像。 此外，采用基于图的分割和比较技术来检测2D图像的前景，从而可以从前景和背景信息生成相对深度图。 因此，3D内容可以提供2D图像加上深度信息。 因此，用户可以自动从2D图像快速获得3D内容，并可以实现3D内容的渲染。

公开(公告)号：US20090085254A1

公开(公告)日：2009-04-02

申请号：US11904697

申请日：2007-09-28

申请人： Anatoli Anatolyevich Abramov ,  Weiwei Luo ,  Qi Wu ,  Wei Xu ,  Naiyue Zhou

发明人： Anatoli Anatolyevich Abramov ,  Weiwei Luo ,  Qi Wu ,  Wei Xu ,  Naiyue Zhou

IPC分类号： B29C35/08

CPC分类号： C03B33/093 ,  C03B33/0222 ,  C03B33/091

摘要： Disclosed are systems and methods for scoring glass sheets. A laser beam can be generated having a substantially uniform peak energy density along at least a portion of its length. The laser beam is moved across the glass sheet to create a score line. Further, the glass sheet can be separated along the score line. In some aspects, the laser beam is bimodal and comprises approximately 60-70% TEM00 mode and approximately 30-40% TEM01* mode.

摘要翻译： 公开了用于评分玻璃板的系统和方法。 可以产生沿其长度的至少一部分具有基本均匀的峰值能量密度的激光束。 激光束移动穿过玻璃板以创建刻痕线。 此外，玻璃板可以沿着刻痕线分离。 在一些方面，激光束是双峰的并且包括大约60-70％的TEM00模式和大约30-40％的TEM01 *模式。

公开(公告)号：US06608276B2

公开(公告)日：2003-08-19

申请号：US09822153

申请日：2001-03-30

申请人： Qi Wu

发明人： Qi Wu

IPC分类号： B23K2604

CPC分类号： G01J1/32 ,  B23K26/032 ,  B23K26/034 ,  G01J2005/0081 ,  G01N21/718 ,  G02B6/2551 ,  G02B6/2552 ,  H01S3/0675

摘要： A heating apparatus includes: (i) a laser providing at least one beam of light capable of heating a small area of an object; (ii) a laser driver adapted to adjust optical power of this beam of light; (iii) a photo-detector adapted to detect and measure thermal radiation from the small area; and (iv) a control loop operatively linked to the laser driver and the photo-detector, the control loop providing a signal to the laser driver to adjust optical power of the beam of light based on amount thermal radiation detected by the photo-detector. According to one embodiment of the present the laser is a CO2 laser and the small area is less than 0.25 mm in width. According to another embodiment it is a Nd: YAG laser.

摘要翻译： 一种加热装置包括：（i）提供能够加热物体的小面积的至少一束光的激光; （ii）适于调节该光束的光功率的激光驱动器; （iii）适于检测和测量来自该小区域的热辐射的光检测器; 以及（iv）可操作地连接到激光驱动器和光检测器的控制回路，所述控制回路基于由光检测器检测到的热辐射量，向激光驱动器提供信号以调节光束的光功率。 根据本发明的一个实施例，激光器是CO2激光器，并且小面积的宽度小于0.25mm。 根据另一实施例，它是Nd：YAG激光器。

公开(公告)号：US09226281B2

公开(公告)日：2015-12-29

申请号：US13519758

申请日：2010-12-23

申请人： Hai Wang ,  Qi Wu ,  Seong-Hyeon Chae ,  Xufeng Zheng

发明人： Hai Wang ,  Qi Wu ,  Seong-Hyeon Chae ,  Xufeng Zheng

IPC分类号： H04W72/04

CPC分类号： H04W72/042

摘要： A method, a transmitter and a receiver for generating a resource allocation indication message are provided. The method includes, if M serving zones provide one of at least two service types, mapping each of one of N and N−1 resource units to a resource mapping identity represented by one bit, and generating the resource allocation indication message using at least one resource mapping identity, wherein the resource allocation indication message indicates the allocation of N resource units numbered for M serving zones, wherein the M is an integer equal to or larger than 1, and wherein the N is an integer equal to or larger than M.

摘要翻译： 提供了一种用于生成资源分配指示消息的方法，发送器和接收器。 该方法包括：如果M个服务区域提供至少两种服务类型中的一种，将N个和N-1个资源单元之一映射到由一个比特表示的资源映射标识，并使用至少一个 资源映射标识，其中所述资源分配指示消息指示为M个服务区域编号的N个资源单元的分配，其中，M是等于或大于1的整数，并且其中N是等于或大于M的整数。

公开(公告)号：US08912973B2

公开(公告)日：2014-12-16

申请号：US13464492

申请日：2012-05-04

申请人： Douglas H. Werner ,  Erik Lier ,  Bonnie G. Martin ,  Jeremiah P. Turpin ,  Qi Wu

发明人： Douglas H. Werner ,  Erik Lier ,  Bonnie G. Martin ,  Jeremiah P. Turpin ,  Qi Wu

IPC分类号： H01Q21/00 ,  H01Q15/02 ,  H01Q19/06 ,  H01Q15/00

CPC分类号： H01Q15/02 ,  H01Q15/0053 ,  H01Q19/062

摘要： Examples of the present invention include metamaterials, including metamaterial lenses, having material properties that approximate the behavior of a material with low (0

摘要翻译： 本发明的实例包括超材料，包括超材料透镜，具有近似具有低（0

公开(公告)号：US08654697B2

公开(公告)日：2014-02-18

申请号：US12704835

申请日：2010-02-12

申请人： Qi Wu ,  Hai Wang

发明人： Qi Wu ,  Hai Wang

IPC分类号： H04H20/71 ,  H04L12/28 ,  H04L12/56

CPC分类号： H04L1/1829 ,  H04L2001/0092 ,  H04W4/06

摘要： An intelligent assisted transmission method is provided. In the method, a Multicast and Broadcast Service (MCBCS) Server transmits Multicast Broadcast Service (MBS) data to a base station in an MBS area. The base station transmits the MBS data to a user equipment. If the user equipment cannot correctly receive the MBS data, it returns a Not Acknowledgement (NACK) message to the base station. The base station transmits an intelligent assisted transmission prompt to the MCBCS Server. The MCBCS Server transmits an intelligent assisted transmission request to adjacent base stations of the base station. When the intelligent assisted transmission request is received, the adjacent base stations return an intelligent assisted transmission response. The MCBCS Server transmits the MBS data to the adjacent base stations, and the adjacent base stations transmit the MBS data to the user equipment.

摘要翻译： 提供智能辅助传输方法。 在该方法中，多播和广播服务（MCBCS）服务器向MBS区域中的基站发送组播广播服务（MBS）数据。 基站向用户设备发送MBS数据。 如果用户设备无法正确接收MBS数据，则向基站返回不确认（NACK）消息。 基站向MCBCS服务器发送智能辅助传输提示。 MCBCS服务器向基站的相邻基站发送智能辅助传输请求。 当接收到智能辅助传输请求时，相邻基站返回智能辅助传输响应。 MCBCS服务器将MBS数据发送到相邻的基站，相邻的基站向用户设备发送MBS数据。

公开(公告)号：US08510082B2

公开(公告)日：2013-08-13

申请号：US13151605

申请日：2011-06-02

申请人： Jacques Gollier ,  Garrett A. Piech ,  Michael B. Webb ,  Qi Wu

发明人： Jacques Gollier ,  Garrett A. Piech ,  Michael B. Webb ,  Qi Wu

IPC分类号： H03F1/26

CPC分类号： G01J3/28 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/1895 ,  G01J3/2803 ,  G01N21/7743

摘要： An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects. In one embodiment, the optical interrogation system is capable of interrogating a biosensor and using an oversampling/smoothing algorithm to reduce oscillations in the estimated location of an optical resonance caused by the problematical pixelation effect which makes it easier to determine whether or not a biological event occurred on the biosensor.

摘要翻译： 本文描述了一种光询问系统，其可以询问标签无关检测（LID）生物传感器并在生物传感器顶部监测生物事件，而不会遇到有问题的寄生反射和/或有问题的像素化效应。 在一个实施例中，光学询问系统能够询问生物传感器并使用过采样/平滑算法来减少由有问题的像素化效应引起的光学共振的估计位置中的振荡，这使得更容易确定生物事件 发生在生物传感器上。