摘要:
The invention discloses 726 novel phosphorylation sites identified in carcinoma and leukemia, peptides (including AQUA peptides) comprising a phosphorylation site of the invention, antibodies that specifically bind to a novel phosphorylation site of the invention, and diagnostic and therapeutic uses of the above.
摘要:
The exemplary embodiments disclosed herein incorporate transistor heating technology to create micro-heater arrays as the digital heating element for various marking applications. The transistor heaters are typically fabricated either on a thin flexible substrate or on an amorphous silicon drum and embedded below the working surface. Matrix drive methods may be used to address each individual micro-heater and deliver heat to selected surface areas. Depending on different marking applications, the digital heating element may be used to selectively tune the wettability of thermo-sensitive coating, selectively change ink rheology, selectively remove liquid from the surface, selectively fuse/fix toner/ink on the paper.
摘要:
The present invention provides an instrument for anorectal surgery, comprising a hollow main body, a suture junction disposed at a rear end of the main body and an inserting guider disposed at a front end of the main body. At an operating position, all or part of mucosa and tissues can get through the main body. At least one opening is made in the wall of the main body, and all or part of the mucosa and tissues can get into a hollow interior of the main body through the opening. Because of the openings on the wall of the main body, the present invention can be operated to perform the anorectal surgery of local and non-annular cutting, which facilitates a quick surgical operation, further allays the pain of the patients, and a better operation effect is obtained.
摘要:
An imaging member is disclosed having a surface layer comprising a heat-sensitive material whose surface compatibility to printing agents, such as toners and inks, can be substantially reversed in response to small changes in temperature. The imaging member is suitable for use in lithographic and printing applications, permitting reversible switching between compatibility states of printing agents, such as between hydrophilic and hydrophobic states or oleophilic and oleophobic states, and enabling rapid production of images on a recording medium.
摘要:
A method of predicting user purchase intent from user-centric data includes applying a classification model to a user-centric clickstream, where the classification model predicting a likelihood of a future user purchase by a user within one or more product categories, and customizing content displayed to the user based on the likelihood of future user purchase. A system of predicting user purchase intent from user-centric data includes a computer programmed to record a user's clickstream data as a user accesses a plurality of different websites. The computer is also loaded with a classification model configured to predict a likelihood of a future user purchase by the user within one or more product categories based on the clickstream data. A method of predicting user purchase intent from user-centric data includes, with a user's own computer, recording user-centric clickstream data based on visits to a plurality of different websites; and storing a smart cooked based on the clickstream data on the user's own computer.
摘要:
The charged-particle beam system includes a non-axisymmetric diode forms a non-axisymmetric beam having an elliptic cross-section. A focusing element utilizes a magnetic field for focusing and transporting the non-axisymmetric beam, wherein the non-axisymmetric beam is approximately matched with the channel of the focusing element.
摘要:
The present invention provides a method for in vitro detection of malignant potential of dysplasia by aberrant methylation of p16 CpG islands, comprising extraction of genomic DNA from a tissue or body fluid sample, analysis of methylation status of p16 CpG islands in the extracted DNA, and evaluation of malignant potential of the tested tissue. The present invention also provides DNA compositions having artificial sequences of p16 CpG islands with or without methylation.
摘要:
The charged-particle beam system includes a non-axisymmetric diode forms a non-axisymmetric beam having an elliptic cross-section. A focusing element utilizes a magnetic field for focusing and transporting the non-axisymmetric beam, wherein the non-axisymmetric beam is approximately matched with the channel of the focusing element.
摘要:
Compositions and methods for promoting weight management are taught by the present invention. Preferably, the methods include the step of administering a composition of bio-active compounds further including 4-hydroxyisoleucine and one or more amino acids selected from the group consisting of arginine, aspartate, threonine, serine, glutamate, proline, glycine, alanine, cysteine, valine, methionine, isoleucine, leucine, tryptophan, phenylalanine, ornithine, lysine, histidine, and gamma-aminobutyrate. In one presently preferred embodiment of the present invention, the bio-active compounds are extracted from fenugreek seeds. The methods of the present invention preferably include a composition of bio-active compounds with between about 10% and 70% of 4-hydroxyisoleucine and between about 20% and 40% of the amino acids. In presently preferred embodiments of the present invention, methods may work independently of or synergistically with insulin to stimulate the activity of glucose transport receptors located in muscle. More particularly, methods of the present invention may stimulate the activity of glucose transport receptor type 4. In another presently preferred embodiment of the present invention, a method for weight management includes the steps of: (1) performing a weight management analysis on an individual experiencing nutritional and metabolic deficiencies which impact proper metabolism of glucose and carbohydrates; (2) extracting a composition of bio-active compounds from fenugreek; and (3) administering the composition of bio-active compounds from fenugreek in an amount effective to enhance muscle glucose transportation within the body of the individual.
摘要:
The present invention relates to recombinant DNA that encodes the BsmBI restriction endonuclease as well as BsmBI methyltransferase, expression of BsmBI restriction endonuclease and BsmBI methylase in E. coli cells containing the recombinant DNA. It also relates to a method for purification of the recombinant BsmBI restriction endonuclease.