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公开(公告)号：US5110596A
公开(公告)日：1992-05-05
申请号：US513330
申请日：1990-04-20
CPC分类号： A61K9/0004 , A61M31/002
摘要： A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
摘要翻译： 公开了用于将有益剂递送到动物的递送系统。 递送系统包括围绕内腔的壁，所述壁包括限制流体进入系统的组合物和允许流体进入系统的组合物。 管腔包括有益剂和可膨胀构件。 递送系统包括用于递送有益剂的出口装置。
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公开(公告)号：US06180129B2
公开(公告)日：2001-01-30
申请号：US08956424
申请日：1997-10-23
IPC分类号： A61K914
CPC分类号： A61K9/0004 , A61M31/002
摘要： A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
摘要翻译： 公开了用于将有益剂递送到动物的递送系统。 递送系统包括围绕内腔的壁，所述壁包括限制流体进入系统的组合物和允许流体进入系统的组合物。 管腔包括有益剂和可膨胀构件。 递送系统包括用于递送有益剂的出口装置。
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公开(公告)号：US5037420A
公开(公告)日：1991-08-06
申请号：US513328
申请日：1990-04-20
CPC分类号： A61M31/002 , A61K9/0004
摘要： A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
摘要翻译： 公开了用于将有益剂递送到动物的递送系统。 递送系统包括围绕内腔的壁，所述壁包括限制流体进入系统的组合物和允许流体进入系统的组合物。 管腔包括有益剂和可膨胀构件。 递送系统包括用于递送有益剂的出口装置。
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公开(公告)号：US5174999A
公开(公告)日：1992-12-29
申请号：US512301
申请日：1990-04-20
CPC分类号： A61K9/0004 , A61M31/002
摘要： A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
摘要翻译： 公开了用于将有益剂递送到动物的递送系统。 递送系统包括围绕内腔的壁，所述壁包括限制流体进入系统的组合物和允许流体进入系统的组合物。 管腔包括有益剂和可膨胀构件。 递送系统包括用于递送有益剂的出口装置。
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公开(公告)号：US5034229A
公开(公告)日：1991-07-23
申请号：US283359
申请日：1988-12-13
CPC分类号： A61K9/0004 , A61M31/002
摘要： A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
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公开(公告)号：US4996060A
公开(公告)日：1991-02-26
申请号：US334251
申请日：1989-04-06
CPC分类号： A61K38/27 , A61K9/0004
摘要： A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.
摘要翻译： 公开了用于将有益剂递送到动物的递送装置。 该装置包括容纳内部空间的壁，该空间中的有益试剂，该空间中的可膨胀装置，用于使有益试剂从该装置输送，并在该空间中用于屏蔽有益试剂免受流体侵害的装置。
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17.发明授权Device comprising means for protecting and dispensing fluid sensitive medicament 失效装置包括用于保护和分配流体敏感药物的装置
公开(公告)号：US4855141A
公开(公告)日：1989-08-08
申请号：US173209
申请日：1988-03-25
CPC分类号： A61K9/0004 , A61K38/27
摘要： A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.
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公开(公告)号：US5059423A
公开(公告)日：1991-10-22
申请号：US513528
申请日：1990-04-23
CPC分类号： A61K9/0004 , A61M31/002
摘要： A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
摘要翻译： 公开了用于将有益剂递送到动物的递送系统。 递送系统包括围绕内腔的壁，所述壁包括限制流体进入系统的组合物和允许流体进入系统的组合物。 管腔包括有益剂和可膨胀构件。 递送系统包括用于递送有益剂的出口装置。
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公开(公告)号：US4959218A
公开(公告)日：1990-09-25
申请号：US291930
申请日：1988-12-28
CPC分类号： A61K9/0004 , A61K38/27
摘要： A delivery device is disclosed for delivering a beneficial agent to an animal. The device comprises a wall housing an internal space, a beneficial agent in the space, expandable means in the space for causing the beneficial agent to be delivered from the device and means in the space for shielding the beneficial agent from fluid.
摘要翻译： 公开了用于将有益剂递送到动物的递送装置。 该装置包括容纳内部空间的壁，该空间中的有益试剂，该空间中的可膨胀装置，用于使有益试剂从该装置输送，并在该空间中用于屏蔽有益试剂免受流体侵害的装置。
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公开(公告)号：US07655257B2
公开(公告)日：2010-02-02
申请号：US10645293
申请日：2003-08-20
申请人： John R. Peery , Keith E. Dionne , James B. Eckenhoff , Bonnie J. Eckenhoff, legal representative , Felix A. Landrau , Scott D. Lautenbach , Judy A. Magruder , Jeremy C. Wright
发明人： John R. Peery , Keith E. Dionne , James B. Eckenhoff , Felix A. Landrau , Scott D. Lautenbach , Judy A. Magruder , Jeremy C. Wright
CPC分类号： A61M5/14526 , A61K9/0004 , A61K9/0024 , A61K38/09 , A61M2005/14513 , A61M2206/10
摘要： The invention is directed to a device for delivering an active agent formulation for a predetermined administration period. An impermeable reservoir is divided into a water-swellable agent chamber and an active agent formulation chamber. Fluid from the environment is imbibed through a semipermeable plug into the water-swellable agent chamber and the active agent formulation is released through a back-diffusion regulating outlet. Delivery periods of up to 2 years are achieved.
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