公开(公告)号：US20050137647A1

公开(公告)日：2005-06-23

申请号：US10744853

申请日：2003-12-22

申请人： Michael Wallace ,  Kamal Ramzipoor ,  Robert Garabedian ,  Robert Abrams

发明人： Michael Wallace ,  Kamal Ramzipoor ,  Robert Garabedian ,  Robert Abrams

IPC分类号： A61N1/05 ,  A61N1/18

CPC分类号： A61N1/0529 ,  A61N1/0531 ,  A61N1/0534

摘要： A method of treating a disorder in a patient is provided. The method comprises delivering a stimulation lead within a blood vessel, intralumenally puncturing a wall of the blood vessel to create an exit point, and then introducing the stimulation lead through the exit point into direct contact with tissue the stimulation of which treats the disorder. Optionally, the method comprises implanting a source of stimulation within the patient's body, and then electrically coupling the proximal end of the stimulation lead to the implanted stimulation source. Using the stimulation lead, the tissue can then be stimulated in order to treat the disorder.

摘要翻译： 提供了一种治疗患者疾病的方法。 该方法包括在血管内递送刺激引线，腔内穿刺血管的壁以产生出口点，然后将刺激引线通过出口点直接接触组织，其刺激治疗病症。 可选地，该方法包括将刺激源植入患者体内，然后将刺激引线的近端电耦合到植入的刺激源。 使用刺激铅，然后可以刺激组织以治疗该疾病。

公开(公告)号：US06478773B1

公开(公告)日：2002-11-12

申请号：US09501466

申请日：2000-02-09

申请人： Deepak Gandhi ,  Kamal Ramzipoor

发明人： Deepak Gandhi ,  Kamal Ramzipoor

IPC分类号： A61F712

CPC分类号： A61B17/12113 ,  A61B17/12 ,  A61B17/12022 ,  A61B17/12136 ,  A61B17/1214 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/12068 ,  A61B2017/12077 ,  A61B2017/1209 ,  A61B2018/00005 ,  A61B2090/037 ,  A61F2002/9505 ,  A61F2002/9511

摘要： The apparatus for deployment of a therapeutic device such as a micro-coil detachably mounts the therapeutic device to a distal portion of a pusher member. In one embodiment, the therapeutic device is detachably mounted to the distal portion of the pusher member by a tubular collar that can be heated by a heater such as an electrical resistance coil to expand the collar and release and deploy the therapeutic device. The apparatus for deployment of a therapeutic device such as a micro-coil may also provide for a pusher member and a connector fiber for securing the therapeutic device to the pusher member. The connector fiber passes through a heater within the distal portion of the pusher member, for heating and breaking the connector fiber to release the therapeutic device when a desired placement of the therapeutic device within the vasculature is achieved.

摘要翻译： 用于展开诸如微型线圈的治疗装置的装置将治疗装置可拆卸地安装到推动器构件的远侧部分。 在一个实施例中，治疗装置通过可被诸如电阻线圈的加热器加热的管状套环可拆卸地安装到推动器构件的远端部分，以扩大套环并释放和展开治疗装置。 用于展开诸如微型线圈的治疗装置的装置还可以提供用于将治疗装置固定到推动器构件的推动器构件和连接器纤维。 连接器纤维通过在推动器构件的远端部分内的加热器，用于加热和断开连接器纤维以在实现治疗装置在脉管系统期望的放置期间释放治疗装置。

公开(公告)号：US08974513B2

公开(公告)日：2015-03-10

申请号：US13540514

申请日：2012-07-02

申请人： Russell Ford ,  Scott McGill ,  Clifford Teoh ,  Michael Williams ,  Kamal Ramzipoor ,  Like Que ,  Ann Huang ,  Elena Oo ,  Christina Ma ,  Stella Chu

发明人： Russell Ford ,  Scott McGill ,  Clifford Teoh ,  Michael Williams ,  Kamal Ramzipoor ,  Like Que ,  Ann Huang ,  Elena Oo ,  Christina Ma ,  Stella Chu

IPC分类号： A61F2/06 ,  A61B17/12 ,  A61B17/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/12154 ,  A61B2017/00022 ,  A61B2017/12063

摘要： An implant assembly comprises an elongated pusher member, and an implantable device (e.g., a vaso-occlusive device) mounted to the distal end of the pusher member. The implant assembly further comprises an electrolytically severable joint disposed on the pusher member, wherein the implantable device detaches from the pusher member when the severable joint is severed, and a return electrode carried by the distal end of the pusher member (e.g., a coil disposed about the pusher member) in proximity to, but electrically isolated from, the severable joint. The implant assembly further comprises a terminal carried by the proximal end of the pusher member in electrical communication with the severable joint.

摘要翻译： 植入物组件包括细长的推动器构件和安装到推动器构件的远端的可植入装置（例如，血管闭塞装置）。 植入物组件还包括设置在推动器构件上的电解可分离的接头，其中当可切断接头被切断时，可植入装置与推动器构件分离，以及由推动器构件的远端（例如，线圈设置 围绕推动器构件）接近，但是与可分开的接头电隔离。 植入物组件还包括由推动器构件的近端承载的端子，其与可分离接头电连通。

公开(公告)号：US20120184979A1

公开(公告)日：2012-07-19

申请号：US13356605

申请日：2012-01-23

申请人： Deepak Gandhi ,  Kamal Ramzipoor

发明人： Deepak Gandhi ,  Kamal Ramzipoor

IPC分类号： A61M29/00

CPC分类号： A61B17/12113 ,  A61B17/12 ,  A61B17/12022 ,  A61B17/12136 ,  A61B17/1214 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/12068 ,  A61B2017/12077 ,  A61B2017/1209 ,  A61B2018/00005 ,  A61B2090/037 ,  A61F2002/9505 ,  A61F2002/9511

摘要： The apparatus for deployment of a therapeutic device such as a micro-coil detachably mounts the therapeutic device to a distal portion of a pusher member. In one embodiment, the therapeutic device is detachably mounted to the distal portion of the pusher member by a tubular collar that can be heated by a heater such as an electrical resistance coil to expand the collar and release and deploy the therapeutic device. The apparatus for deployment of a therapeutic device such as a micro-coil may also provide for a pusher member and a connector fiber for securing the therapeutic device to the pusher member. The connector fiber passes through a heater within the distal portion of the pusher member, for heating and breaking the connector fiber to release the therapeutic device when a desired placement of the therapeutic device within the vasculature is achieved.

摘要翻译： 用于展开诸如微型线圈的治疗装置的装置将治疗装置可拆卸地安装到推动器构件的远侧部分。 在一个实施例中，治疗装置通过可被诸如电阻线圈的加热器加热的管状套环可拆卸地安装到推动器构件的远端部分，以扩大套环并释放和展开治疗装置。 用于展开诸如微型线圈的治疗装置的装置还可以提供用于将治疗装置固定到推动器构件的推动器构件和连接器纤维。 连接器纤维通过在推动器构件的远端部分内的加热器，用于加热和断开连接器纤维以在实现治疗装置在脉管系统期望的放置期间释放治疗装置。

公开(公告)号：US08221483B2

公开(公告)日：2012-07-17

申请号：US12122636

申请日：2008-05-16

申请人： Russell Ford ,  Scott McGill ,  Clifford Teoh ,  Michael Williams ,  Kamal Ramzipoor ,  Like Que ,  Ann Huang ,  Elena Oo ,  Christina Ma ,  Stella Chu

发明人： Russell Ford ,  Scott McGill ,  Clifford Teoh ,  Michael Williams ,  Kamal Ramzipoor ,  Like Que ,  Ann Huang ,  Elena Oo ,  Christina Ma ,  Stella Chu

IPC分类号： A61F2/06

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/12154 ,  A61B2017/00022 ,  A61B2017/12063

摘要： An implant assembly comprises an elongated pusher member, and an implantable device (e.g., a vaso-occlusive device) mounted to the distal end of the pusher member. The implant assembly further comprises an electrolytically severable joint disposed on the pusher member, wherein the implantable device detaches from the pusher member when the severable joint is severed, and a return electrode carried by the distal end of the pusher member (e.g., a coil disposed about the pusher member) in proximity to, but electrically isolated from, the severable joint. The implant assembly further comprises a terminal carried by the proximal end of the pusher member in electrical communication with the severable joint.

摘要翻译： 植入物组件包括细长的推动器构件和安装到推动器构件的远端的可植入装置（例如，血管闭塞装置）。 植入物组件还包括设置在推动器构件上的电解可分离的接头，其中当可切断接头被切断时，可植入装置与推动器构件分离，以及由推动器构件的远端（例如，线圈设置 围绕推动器构件）接近，但是与可分开的接头电隔离。 植入物组件还包括由推动器构件的近端承载的端子，其与可分离接头电连通。

公开(公告)号：US07776054B2

公开(公告)日：2010-08-17

申请号：US12541057

申请日：2009-08-13

申请人： Deepak Gandhi ,  Kamal Ramzipoor

发明人： Deepak Gandhi ,  Kamal Ramzipoor

IPC分类号： A61F11/00 ,  A61F7/12 ,  A61M29/00

CPC分类号： A61B17/12113 ,  A61B17/12 ,  A61B17/12022 ,  A61B17/12136 ,  A61B17/1214 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/12068 ,  A61B2017/12077 ,  A61B2017/1209 ,  A61B2018/00005 ,  A61B2090/037 ,  A61F2002/9505 ,  A61F2002/9511

摘要： The apparatus for deployment of a therapeutic device such as a micro-coil detachably mounts the therapeutic device to a distal portion of a pusher member. In one embodiment, the therapeutic device is detachably mounted to the distal portion of the pusher member by a tubular collar that can be heated by a heater such as an electrical resistance coil to expand the collar and release and deploy the therapeutic device. The apparatus for deployment of a therapeutic device such as a micro-coil may also provide for a pusher member and a connector fiber for securing the therapeutic device to the pusher member. The connector fiber passes through a heater within the distal portion of the pusher member, for heating and breaking the connector fiber to release the therapeutic device when a desired placement of the therapeutic device within the vasculature is achieved.

公开(公告)号：US20100004731A1

公开(公告)日：2010-01-07

申请号：US12544977

申请日：2009-08-20

申请人： Deepak Gandhi ,  Kamal Ramzipoor

发明人： Deepak Gandhi ,  Kamal Ramzipoor

IPC分类号： A61F2/06

CPC分类号： A61B17/12113 ,  A61B17/12 ,  A61B17/12022 ,  A61B17/12136 ,  A61B17/1214 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/12068 ,  A61B2017/12077 ,  A61B2017/1209 ,  A61B2018/00005 ,  A61B2090/037 ,  A61F2002/9505 ,  A61F2002/9511

摘要： The apparatus for deployment of a therapeutic device such as a micro-coil detachably mounts the therapeutic device to a distal portion of a pusher member. In one embodiment, the therapeutic device is detachably mounted to the distal portion of the pusher member by a tubular collar that can be heated by a heater such as an electrical resistance coil to expand the collar and release and deploy the therapeutic device. The apparatus for deployment of a therapeutic device such as a micro-coil may also provide for a pusher member and a connector fiber for securing the therapeutic device to the pusher member. The connector fiber passes through a heater within the distal portion of the pusher member, for heating and breaking the connector fiber to release the therapeutic device when a desired placement of the therapeutic device within the vasculature is achieved.

公开(公告)号：US07608089B2

公开(公告)日：2009-10-27

申请号：US11022189

申请日：2004-12-22

申请人： Michael P. Wallace ,  Kamal Ramzipoor

发明人： Michael P. Wallace ,  Kamal Ramzipoor

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/12154 ,  A61B2017/00477 ,  A61B2017/12054 ,  A61B2017/12063 ,  A61B2017/12095

摘要： An assembly for occluding a vascular site (e.g., an aneurysm) of a human or veterinary patient includes a vaso-occlusive member, a pusher member having a distal end and a severable junction located proximal to the distal end, and a pivotable coupling that couples the pusher member to the occlusive member. A delivery catheter can be used to deliver the vaso-occlusive member to the vascular site. A method of using the assembly to occlude an aneurysm having an aneurysmal sac and an aneurysmal neck, includes locating the catheter within the aneurysmal neck, and manipulating the pusher member to place the vaso-occlusive member within the aneurysmal sac. The method further includes severing the severable junction to detach the vaso-occlusive member from the pusher member. As a result, an axial force is applied by the vaso-occlusive member in a proximal direction, which buckles the pivotable coupling to laterally deflect the axial force. The lateral deflection of the axial force caused by the buckling of the pivotable coupling prevents the catheter from being displaced from the aneurysmal neck by the axial force.

摘要翻译： 用于闭塞人或兽医患者的血管部位（例如，动脉瘤）的组件包括血管闭塞构件，具有远端的推动器构件和位于远端附近的可分离接合部以及可枢转联接件 推动器构件到闭塞构件。 输送导管可用于将血管闭塞成员递送至血管部位。 一种使用组件闭塞具有动脉瘤囊和动脉瘤颈部的动脉瘤的方法，包括将导管定位在动脉瘤颈内，以及操纵推动器构件以将血管闭塞构件置于动脉瘤囊内。 该方法还包括切断可分开的连接处以将血管闭塞构件与推动器构件分离。 结果，轴向力由近端方向由血管闭塞构件施加，该近侧方向使可枢转联接器弯曲以横向偏转轴向力。 由可枢转联轴器的弯曲引起的轴向力的横向偏转防止导管通过轴向力从动脉瘤颈部移位。

公开(公告)号：US07575582B2

公开(公告)日：2009-08-18

申请号：US11435362

申请日：2006-05-16

申请人： Deepak Gandhi ,  Kamal Ramzipoor

发明人： Deepak Gandhi ,  Kamal Ramzipoor

IPC分类号： A61F11/00 ,  A61F7/12 ,  A61M29/00

CPC分类号： A61B17/12113 ,  A61B17/12 ,  A61B17/12022 ,  A61B17/12136 ,  A61B17/1214 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/12068 ,  A61B2017/12077 ,  A61B2017/1209 ,  A61B2018/00005 ,  A61B2090/037 ,  A61F2002/9505 ,  A61F2002/9511

摘要： The apparatus for deployment of a therapeutic device such as a micro-coil detachably mounts the therapeutic device to a distal portion of a pusher member. In one embodiment, the therapeutic device is detachably mounted to the distal portion of the pusher member by a tubular collar that can be heated by a heater such as an electrical resistance coil to expand the collar and release and deploy the therapeutic device. The apparatus for deployment of a therapeutic device such as a micro-coil may also provide for a pusher member and a connector fiber for securing the therapeutic device to the pusher member. The connector fiber passes through a heater within the distal portion of the pusher member, for heating and breaking the connector fiber to release the therapeutic device when a desired placement of the therapeutic device within the vasculature is achieved.

公开(公告)号：US20070055302A1

公开(公告)日：2007-03-08

申请号：US11423934

申请日：2006-06-13

申请人： William Henry ,  Charles Daly ,  Russell Ford ,  Michael Williams ,  Hanh Duong ,  Hughie Devaney ,  Kamal Ramzipoor ,  Clifford Teoh ,  Richard Murphy ,  Andrew Huffmaster ,  Scott McGill

发明人： William Henry ,  Charles Daly ,  Russell Ford ,  Michael Williams ,  Hanh Duong ,  Hughie Devaney ,  Kamal Ramzipoor ,  Clifford Teoh ,  Richard Murphy ,  Andrew Huffmaster ,  Scott McGill

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/12154 ,  A61B2017/1205 ,  A61B2017/12054 ,  A61B2017/12063 ,  A61M25/09 ,  A61M2025/09133

摘要： A device for delivering an occlusive element includes an elongate sheath having a lumen therein. An elongate core member is disposed within the lumen and is formed from a proximal portion and distal portion connected via a joint. The distal portion of the elongate member includes a severable junction secured to the occlusive element. A marker coil is coaxially arranged around the distal portion of the elongate core member and is partially disposed inside the sheath lumen. A coil member is coaxially arranged around the distal portion of the elongate core member and coaxially arranged around at least a portion of the marker coil extending outside the lumen of the sheath. The coil member is secured at a distal end thereof to the distal portion of the elongate core member. The device resists axial compression while allowing for radial bending.

摘要翻译： 用于递送闭塞元件的装置包括其中具有内腔的细长护套。 细长的芯构件设置在内腔内，并且由通过接头连接的近端部分和远端部分形成。 细长构件的远端部分包括固定到闭塞元件的可分开的连接点。 标记线圈围绕细长芯构件的远端部分同轴布置，并且部分地设置在鞘腔内。 线圈构件围绕细长芯构件的远侧部分同轴地布置，并且围绕标记线圈的至少一部分同轴地布置，该标记线圈延伸到护套内腔的外侧。 线圈构件在其远端固定到细长芯构件的远端部分。 该装置抵抗轴向压缩同时允许径向弯曲。