Biosensor and method of driving the same
    12.
    发明授权
    Biosensor and method of driving the same 失效
    生物传感器及其驱动方法

    公开(公告)号:US08164123B2

    公开(公告)日:2012-04-24

    申请号:US12703939

    申请日:2010-02-11

    IPC分类号: H01L29/78 H01L29/772

    CPC分类号: G01N27/4145

    摘要: Provided are a biosensor and a method of driving the same. The biosensor includes a transistor including a substrate including a source, a drain, and a channel formed between the source and the drain, a gate insulating layer formed on the channel, and a source electrode and a drain electrode respectively connected with the source and the drain, a fluid line for covering the transistor to have an inner space together with the transistor and in which a sample solution including target molecules flows, a reference electrode formed on an inner wall of the fluid line, and a probe molecule layer attached on the reference electrode and reacting with the target molecules. Accordingly, the reference electrode is formed on the inner wall of the fluid line, enabling miniaturization of the bio device. Also, the probe molecules are formed on the reference electrode to measure a change in threshold voltage according to a change in electric potential between the reference electrode and the gate insulating layer, such that the sensitivity and reaction rate can be remarkably improved.

    摘要翻译: 提供了一种生物传感器及其驱动方法。 生物传感器包括晶体管,其包括基板,该基板包括源极,漏极和形成在源极和漏极之间的沟道,形成在沟道上的栅极绝缘层以及分别与源极和漏极连接的源极和漏极 漏极,用于覆盖晶体管的流体线,其与晶体管一起具有内部空间,并且其中包含目标分子的样品溶液流动,形成在流体管线的内壁上的参考电极和附着在该流体管线上的探针分子层 参考电极并与靶分子反应。 因此,参考电极形成在流体管线的内壁上,使生物装置能够小型化。 此外,探针分子形成在参考电极上,以根据参考电极和栅极绝缘层之间的电位的变化来测量阈值电压的变化,从而可以显着提高灵敏度和反应速率。

    Method and apparatus for measuring isoelectric point using field effect transistor
    13.
    发明授权
    Method and apparatus for measuring isoelectric point using field effect transistor 失效
    使用场效应晶体管测量等电点的方法和装置

    公开(公告)号:US08628650B2

    公开(公告)日:2014-01-14

    申请号:US13058120

    申请日:2008-12-16

    IPC分类号: B03C5/02

    CPC分类号: G01N27/4145

    摘要: Provided are a method and apparatus for measuring an isoelectric point using a field effect transistor. The method includes providing a field effect transistor including a substrate, source and drain electrodes disposed on the substrate and spaced apart from each other, and a channel region between the source and drain electrodes, providing a first electrolyte solution having a first concentration to the channel region of the field effect transistor and measuring a first current value of the channel region between the source and drain electrodes, providing a second electrolyte solution having a second concentration greater than the first concentration and measuring a second current value of the channel region between the source and drain electrodes, and determining the isoelectric point of the field effect transistor or a material disposed on the field effect transistor using a difference between the first and second current values.

    摘要翻译: 提供了使用场效应晶体管测量等电点的方法和装置。 该方法包括提供场效应晶体管,该场效应晶体管包括衬底,设置在衬底上的源电极和漏极彼此间隔开的沟道区,以及在源电极和漏电极之间的沟道区域,提供具有第一浓度到沟道的第一电解质溶液 区域,并且测量源极和漏极之间的沟道区的第一电流值,提供具有大于第一浓度的第二浓度的第二电解质溶液,并测量源极之间的沟道区的第二电流值 和漏电极,并且使用第一和第二电流值之间的差来确定场效应晶体管的等电点或设置在场效应晶体管上的材料。

    Sensing device
    14.
    发明授权
    Sensing device 有权
    感应装置

    公开(公告)号:US08426900B2

    公开(公告)日:2013-04-23

    申请号:US13122273

    申请日:2009-05-27

    IPC分类号: G01N27/403

    CPC分类号: G01N27/4145 G01N27/4146

    摘要: Provided is a sensing device, which includes a reactive material layer (260) responding to a specific functional group in a fluid, a sensing capacitor (B) including first and second electrodes disposed on and under an insulating layer (230), the first electrode being disposed under the reactive material layer (260), and a field effect transistor including a gate electrode connected with the first electrode of the sensing capacitor. Here, the reactive material layer (260) is formed in a conductive three-dimensional structure to widen a surface area. Thus, the sensing device may have high sensitivity by maximizing a capacitor sharing effect and a change in voltage amount applied to a gate, which may be caused by widening a surface area of the conductive three-dimensional structure with respect to the fluid flow.

    摘要翻译: 提供了一种感测装置,其包括响应于流体中的特定官能团的反应性材料层(260),包括设置在绝缘层(230)上和下方的第一和第二电极的感测电容器(B),第一电极 设置在反应性材料层(260)下方的场效应晶体管,以及包括与感测电容器的第一电极连接的栅电极的场效应晶体管。 这里,反应性材料层(260)形成为导电三维结构以扩大表面积。 因此,感测装置可以通过最大化电容器共享效应和施加到栅极的电压量的变化而具有高灵敏度,这可能是通过相对于流体流动扩大导电三维结构的表面积而引起的。

    SENSING DEVICE
    15.
    发明申请
    SENSING DEVICE 有权
    感应装置

    公开(公告)号:US20110180856A1

    公开(公告)日:2011-07-28

    申请号:US13122273

    申请日:2009-05-27

    CPC分类号: G01N27/4145 G01N27/4146

    摘要: Provided is a sensing device, which includes a reactive material layer (260) responding to a specific functional group in a fluid, a sensing capacitor (B) including first and second electrodes disposed on and under an insulating layer (230), the first electrode being disposed under the reactive material layer (260), and a field effect transistor including a gate electrode connected with the first electrode of the sensing capacitor. Here, the reactive material layer (260) is formed in a conductive three-dimensional structure to widen a surface area. Thus, the sensing device may have high sensitivity by maximizing a capacitor sharing effect and a change in voltage amount applied to a gate, which may be caused by widening a surface area of the conductive three-dimensional structure with respect to the fluid flow.

    摘要翻译: 提供了一种感测装置,其包括响应于流体中的特定官能团的反应性材料层(260),包括设置在绝缘层(230)上和下方的第一和第二电极的感测电容器(B),第一电极 设置在反应性材料层(260)下方的场效应晶体管,以及包括与感测电容器的第一电极连接的栅电极的场效应晶体管。 这里,反应性材料层(260)形成为导电三维结构以扩大表面积。 因此,感测装置可以通过最大化电容器共享效应和施加到栅极的电压量的变化而具有高灵敏度,这可能是通过相对于流体流动扩大导电三维结构的表面积而引起的。

    CARTRIDGE FOR MEASURING BIOLOGICAL SAMPLE COMPONENT AND APPARATUS FOR MEASURING BIOLOGICAL SAMPLE COMPONENT
    18.
    发明申请
    CARTRIDGE FOR MEASURING BIOLOGICAL SAMPLE COMPONENT AND APPARATUS FOR MEASURING BIOLOGICAL SAMPLE COMPONENT 审中-公开
    用于测量生物样品组分的仪器和用于测量生物样品组分的装置

    公开(公告)号:US20110293479A1

    公开(公告)日:2011-12-01

    申请号:US12950964

    申请日:2010-11-19

    IPC分类号: G01N21/00 G01N33/48

    摘要: A cartridge for measuring a biological sample component and an apparatus for measuring a biological sample component are provided. The cartridge for measuring a biological sample component includes: an upper cartridge having a first chamber storing a biological sample, a first channel connected to the first chamber and delivering air pressure to the first chamber, and a third channel transferring the biological sample; and a lower cartridge having a third chamber storing a first reagent, a fifth chamber storing a second reagent, a fifth channel connecting the third and fifth chambers and transferring the second reagent to the third chamber, an eleventh channel delivering the biological sample delivered through the third channel to the third chamber, and a thirteenth channel delivering air pressure to the fifth chamber, wherein when the upper and lower cartridges are bounded by an external force, the third channel and the eleventh channel are connected.

    摘要翻译: 提供了用于测量生物样品组分的盒和用于测量生物样品组分的装置。 用于测量生物样品组分的盒包括:具有存储生物样品的第一室的上盒,连接到第一室的第一通道并将空气压力输送到第一室,以及传送生物样品的第三通道; 以及具有第三室的下部盒存储第一试剂,存储第二试剂的第五室,连接第三和第五室的第五通道并将第二试剂转移到第三室,第十一通道,其输送通过 第三通道到第三室,以及第十三通道,将空气压力传送到第五室,其中当上部和下部盒被外力界定时,第三通道和第十一通道连接。