公开(公告)号：US11033512B2

公开(公告)日：2021-06-15

申请号：US16623034

申请日：2018-06-25

Applicant: LTS LOHMANN Therapie-Systeme AG

Inventor： Patrick Mohr ,  René Rietscher ,  René Eifler ,  Olga Bourquain

IPC: A61K9/70 ,  A61P25/18 ,  A61K31/407

Abstract: The present invention relates to transdermal therapeutic systems (TTS) for the transdermal administration of asenapine comprising an asenapine-containing layer structure, said asenapine-containing layer structure comprising A) a backing layer and B) an asenapine-containing layer, wherein the transdermal therapeutic system comprises a silicone acrylic hybrid polymer.

公开(公告)号：US09895521B2

公开(公告)日：2018-02-20

申请号：US15042493

申请日：2016-02-12

Applicant: LTS LOHMANN THERAPIE-SYSTEME AG

Inventor： Patrick Mohr

IPC: A61M37/00 ,  A61M5/145

CPC classification number: A61M37/0015 ,  A61M5/14593 ,  A61M2037/0023

Abstract: A transdermal therapeutic system with a system support, at least one advancing element which is embedded into the system support, and at least one active ingredient reservoir which can be elastically deformed at least in some regions and which is embedded into the advancing element. On the application side of the transdermal therapeutic system, the system support surrounds the advancing element, and the advancing element surrounds the active ingredient reservoir. The advancing element comprises a swelling body which can be expanded by means of a liquid intake. The system support is designed to be rigid at least in some regions. A transdermal therapeutic system is developed which enhances the effect of the advancing element.