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14 条记录 (耗时 0.017 秒)

    Substituted sulfonamides
    11.
    发明申请
    Substituted sulfonamides 审中-公开
    取代磺酰胺

    公开(公告)号：US20070105914A1

    公开(公告)日：2007-05-10

    申请号：US10571842

    申请日：2004-09-14

    申请人： Helen Armstrong ,  Linda Chang ,  Ravindra Guthikonda ,  William Hagmann ,  Linus Lin ,  Shrenik Shah

    发明人： Helen Armstrong ,  Linda Chang ,  Ravindra Guthikonda ,  William Hagmann ,  Linus Lin ,  Shrenik Shah

    IPC分类号： A61K31/44 ,  A61K31/277 ,  A61K31/18

    CPC分类号： C07C311/06 ,  A61K31/18 ,  A61K31/277 ,  A61K31/44 ,  C07C311/03 ,  C07C311/13 ,  C07C311/16 ,  C07C311/17 ,  C07C311/19 ,  C07C311/29 ,  C07D209/08

    摘要： The substituted sulfonamides of the invention are antagonists and/or inverse agonists of the Cannabinoid-1 (CB1) receptor and are useful in the treatment, prevention and suppression of diseases mediated by the CB1 receptor. The compounds of the present invention are useful as centrally acting drugs in the treatment of psychosis, memory deficits, cognitive disorders, migraine, neuropathy, neuro-inflammatory disorders including multiple sclerosis and Guillain-Barre syndrome and the inflammatory sequelae of viral encephalitis, cerebral vascular accidents, and head trauma, anxiety disorders, stress, epilepsy, Parkinson's disease, movement disorders, and schizophrenia The compounds are also useful for the treatment of substance abuse disorders, the treatment of obesity or eating disorders, as well as the treatment of asthma, constipation, chronic intestinal pseudo-obstruction, and cirrhosis of the liver.

    摘要翻译： 本发明的取代磺酰胺是大麻素-1（CB1）受体的拮抗剂和/或反向激动剂，可用于治疗，预防和抑制由CB1受体介导的疾病。 本发明的化合物可用作治疗精神病，记忆缺陷，认知障碍，偏头痛，神经病，包括多发性硬化和神经 - 巴利综合征的神经炎症性疾病以及病毒性脑炎的炎症性后遗症，脑血管 事故和头部创伤，焦虑症，压力，癫痫，帕金森病，运动障碍和精神分裂症。该化合物还可用于治疗药物滥用障碍，治疗肥胖或进食障碍，以及治疗哮喘， 便秘，慢性肠假性梗阻和肝硬化。

    Case for a pair of far-sighted eyeglasses
    13.
    发明授权
    Case for a pair of far-sighted eyeglasses 失效
    一副有远见的眼镜的案例

    公开(公告)号：US06431351B1

    公开(公告)日：2002-08-13

    申请号：US09766621

    申请日：2001-01-23

    申请人： Linus Lin

    发明人： Linus Lin

    IPC分类号： B65D7100

    CPC分类号： A45C11/04 ,  A45C11/34

    摘要： A case for a pair of far-sighted eyeglasses includes an upper and a lower half case, a pair of far-sighted eyeglasses and a pen. The upper and the lower half case have a soft cloth, and the lower half case has a position block in an intermediate portion to stabilize the far-sighted eyeglasses with the nose bridge of the far-sighted eyeglasses lying on the position block. The lower half case has a shaped retaining block respectively at two opposite sides for keeping a pen stably. Thus the case contains both the pair of far-sighted eyeglasses and the pen for carrying to wear and write. A hang hook is also provided on an outer surface of the upper half case to be hanged on a pocket.

    摘要翻译： 一对有远见的眼镜的情况包括上半部和下半部，一对有远见的眼镜和一支笔。 上半壳和下半壳具有软布，下半壳在中间部分具有位置块，以使远视眼镜的望远镜眼睛的鼻梁位于位置块上。 下半壳分别在两个相对的两侧具有成形的保持块，用于稳定地保持笔。 因此，这种情况包含一对有远见的眼镜和用于承载和写入的笔。 挂钩还设置在上半壳的外表面上以挂在口袋上。