公开(公告)号：US20190015665A1

公开(公告)日：2019-01-17

申请号：US16110439

申请日：2018-08-23

Applicant: Medtronic, Inc.

Inventor： Timothy J. Denison ,  Pedram Afshar ,  Scott R. Stanslaski

IPC: A61N1/36 ,  A61B5/00 ,  A61B5/048 ,  A61N1/05

Abstract: Systems and method may be used for interfacing with a patient. Systems may include a plurality of electrodes in electrical communication with a processor. The processor may be configured to receive sense signals from electrodes and to determine the reliability of the received signal. A test tone signal comprising a test tone frequency may be applied, and the magnitude of the test tone frequency may be analyzed in the received signal. If it is determined that the magnitude of the test tone frequency is below a threshold, the system may take action, such as lowering the gain on an amplifier. Stimulation signals may be applied to the patient at a stimulation frequency simultaneously with one or both of receiving sense signals and providing the test tone signal.

公开(公告)号：US20180304082A1

公开(公告)日：2018-10-25

申请号：US16023508

申请日：2018-06-29

Applicant: Medtronic, Inc.

Inventor： Pedram Afshar ,  Timothy J. Denison ,  David E. Linde ,  Scott R. Stanslaski

IPC: A61N1/36 ,  G06F19/00 ,  G16H20/40

Abstract: The disclosure describes a method and system or controlling symptoms of patients suffering from Parkinson's Disease. In some examples, one or more biomarkers indicative of a patient's present symptoms are determined. The biomarkers may be used to control therapy delivered to the patient in a closed-loop manner. In addition, biomarkers may be used as an indication of therapy effectiveness.

公开(公告)号：US20160346548A1

公开(公告)日：2016-12-01

申请号：US14725998

申请日：2015-05-29

Applicant: Medtronic, Inc.

Inventor： Timothy J. Denison ,  Pedram Afshar ,  Scott R. Stanslaski

IPC: A61N1/36 ,  A61N1/05 ,  A61B5/048

CPC classification number: A61N1/36135 ,  A61B5/048 ,  A61B5/4082 ,  A61B5/4836 ,  A61B5/7221 ,  A61N1/0534 ,  A61N1/36067

Abstract: Systems and method may be used for interfacing with a patient. Systems may include a plurality of electrodes in electrical communication with a processor. The processor may be configured to receive sense signals from electrodes and to determine the reliability of the received signal. A test tone signal comprising a test tone frequency may be applied, and the magnitude of the test tone frequency may be analyzed in the received signal. If it is determined that the magnitude of the test tone frequency is below a threshold, the system may take action, such as lowering the gain on an amplifier. Stimulation signals may be applied to the patient at a stimulation frequency simultaneously with one or both of receiving sense signals and providing the test tone signal.

Abstract translation: 系统和方法可以用于与患者接口。 系统可以包括与处理器电连通的多个电极。 处理器可以被配置为从电极接收感测信号并且确定接收信号的可靠性。 可以应用包括测试音频率的测试音信号，并且可以在所接收的信号中分析测试音频率的大小。 如果确定测试音频率的幅度低于阈值，则系统可以采取动作，诸如降低放大器的增益。 刺激信号可以以刺激频率与接收感测信号中的一个或两个同时施加到患者，并提供测试音调信号。