公开(公告)号：US20230243834A1

公开(公告)日：2023-08-03

申请号：US17793382

申请日：2021-01-16

Applicant: Mercy BioAnalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: G01N33/574 ,  C12Q1/6886 ,  C12Q1/6804

CPC classification number: G01N33/57449 ,  C12Q1/6804 ,  C12Q1/6886 ,  C12Q2600/158

Abstract: The present disclosure in one aspect provides technologies for detection of ovarian cancer, e.g., early detection of ovarian cancer. In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject determined to have or susceptible to ovarian cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by identifying biomarkers in woman’s blood samples that are associated with therapeutic response.

公开(公告)号：US20220155304A1

公开(公告)日：2022-05-19

申请号：US17435697

申请日：2020-02-28

Applicant: Mercy BioAnalytics, Inc.

Inventor： Joseph Charles Sedlak ,  Laura Teresa Bortolin ,  Daniel Parker Salem

IPC: G01N33/574 ,  G01N33/543 ,  C12Q1/6886 ,  C12Q1/6862 ,  C12Q1/6804

Abstract: The present disclosure provides technologies for target entity detection. One aspect of the present disclosure provides technologies for detection (e.g., early detection) of a disease, disorder, or condition (e.g., cancer). In another aspect, technologies provided herein are useful for selecting and/or monitoring and/or evaluating efficacy of, a treatment administered to a subject in need thereof, e.g., a subject determined to have or susceptible to cancer. In some embodiments, technologies provided herein are useful for development of companion diagnostics, e.g., by measuring tumor burdens and changes in tumor burdens in conjunction with therapeutics.