公开(公告)号：US06224570B1

公开(公告)日：2001-05-01

申请号：US09188633

申请日：1998-11-09

申请人： Hieu V. Le ,  Michael J. Bonnette ,  John Edward Morris ,  Steven E. Wiesel ,  Debra M. Kozak ,  Cindy M. Setum ,  Robert G. Dutcher

发明人： Hieu V. Le ,  Michael J. Bonnette ,  John Edward Morris ,  Steven E. Wiesel ,  Debra M. Kozak ,  Cindy M. Setum ,  Robert G. Dutcher

IPC分类号： A61M5178

CPC分类号： A61B17/32037 ,  A61B2090/034

摘要： A rheolytic thrombectomy catheter and method of using same to remove thrombus from a body vessel or other body cavity. Several embodiments are disclosed. All embodiments include an outer catheter having a lumen and an inner high pressure tube of a size to enable it to be passed through the lumen of the catheter. The distal end of the inner high pressure tube extends beyond the distal end of the catheter and carries a jet cap for directing one or more jets of saline proximally toward the distal end of the catheter. In some embodiments, the catheter has a distally located inwardly directed stationary stop and the inner high pressure tube includes a distally located outwardly directed transitional stop for engaging the inwardly directed stationary stop to thereby position the jet cap at a defined distance from the distal end of the catheter. In other embodiments, a stationary stop is located at the proximal end of the catheter and a transitional stop is carried on the proximal end of the inner high pressure tube. In the embodiments having the stationary and transitional stops located proximally, the inner high pressure tube includes a flow director at its distal end. In use, thrombus is dislodged, entrained, and broken into pieces by the saline jets and evacuated proximally through the lumen of the catheter.

摘要翻译： 一种溶解性血栓切除术导管及其使用方法，从身体血管或其他体腔去除血栓。 公开了几个实施例。 所有实施例包括具有内腔和内部高压管的外导管，其尺寸使其能够穿过导管的内腔。 内部高压管的远端延伸超过导管的远端，并且携带用于将一个或多个盐水向近端引导到导管的远端的喷射帽。 在一些实施例中，导管具有远侧定位的向内指向的固定止动件，并且内部高压管包括远侧定位的向外指向的过渡止动件，用于接合向内指向的固定止动件，从而将喷射盖定位在距离 导管。 在其他实施例中，静止止动件位于导管的近端处，并且过渡停止件承载在内部高压管的近端上。 在具有位于近侧的静止和过渡止动件的实施例中，内部高压管在其远端包括导流器。 在使用中，血栓被移出，夹带并通过盐水喷射器破碎成碎片，并通过导管的内腔向近端排出。

公开(公告)号：US5989210A

公开(公告)日：1999-11-23

申请号：US19728

申请日：1998-02-06

申请人： John Edward Morris ,  Cindy M. Setum ,  William J. Drasler ,  Hieu V. Le ,  Robert G. Dutcher

发明人： John Edward Morris ,  Cindy M. Setum ,  William J. Drasler ,  Hieu V. Le ,  Robert G. Dutcher

IPC分类号： A61B17/22 ,  A61B19/00 ,  A61B17/20

CPC分类号： A61B17/32037 ,  A61B17/32075 ,  A61B2090/034

摘要： A surgical device and method for removal of tissue, such as thrombus, from a vessel in the body. The device has a first tube with a distal open end and an inward directed stop and a second tube with an outward directed stop for engaging the inward directed stop and thereby regulating the relationship between a retrograde jet and the distal open end. Thrombus is dislodged, entrained, and broken into pieces which are evacuated through the first tube.

摘要翻译： 用于从体内的血管中去除诸如血栓的组织的手术装置和方法。 该装置具有第一管，其具有远端开口端和向内指向的止动件，以及具有向外定向止动件的第二管，用于接合向内指向的止动件，从而调节逆行射流与远端开口端之间的关系。 血栓被移出，夹带并分解成通过第一管排出的碎片。

公开(公告)号：US07608063B2

公开(公告)日：2009-10-27

申请号：US11360148

申请日：2006-02-23

申请人： Hieu V. Le ,  Michael P. Schrom ,  Diana L. Dutcher ,  Kyle R. Matson ,  Dean A. Swanson ,  Kathleen C. Grant ,  James T. Klee

发明人： Hieu V. Le ,  Michael P. Schrom ,  Diana L. Dutcher ,  Kyle R. Matson ,  Dean A. Swanson ,  Kathleen C. Grant ,  James T. Klee

IPC分类号： A61M25/00

CPC分类号： A61M25/008 ,  A61B17/22 ,  A61M25/0032 ,  A61M25/0068 ,  A61M2025/0081

摘要： A dual lumen aspiration catheter system with an aspiration catheter, a hub and a flexible strain relief, and a suction assembly. The aspiration catheter includes multiple successively connected flexible tubular components each increasing in relative flexibility in the distal direction, the most proximal tubular component connectingly extending from the hub and through the flexible strain relief. The tubular components of the aspiration catheter include, in order proximally to distally, a composite tube, an intermediate tube, a dual lumen tube, and a flexible tip tube. The dual lumen tube includes eccentrically co-located large and small tubular portions forming eccentrically co-located large and small lumens to provide a minimum cross section. The distal end of the dual lumen tube includes a convex beveled edge. The convex beveled edge and the flexible tip tube singly or jointly inflict minimal traumatic contact with a vessel wall when urged along a tortuous vascular path.

摘要翻译： 具有抽吸导管，轮毂和柔性应变消除装置的双腔抽吸导管系统和抽吸组件。 抽吸导管包括多个连续连接的柔性管状部件，每个柔性管状部件在远端方向上相对柔性增加，最近端的管状部件从轮毂连接延伸并穿过柔性应变消除部。 抽吸导管的管状部件按照向远端方向依次包括复合管，中间管，双腔管和柔性末端管。 双腔管包括偏心地共同定位的大和小管状部分，形成偏心共同定位的大小腔，以提供最小横截面。 双腔管的远端包括凸出的斜边缘。 当沿着曲折的血管路径被推动时，凸出的斜边缘和柔性尖端管单独或联合地与血管壁产生最小的创伤性接触。

公开(公告)号：US06355027B1

公开(公告)日：2002-03-12

申请号：US09328761

申请日：1999-06-09

申请人： Hieu V. Le ,  John Edward Morris ,  Cindy M. Setum ,  Robert G. Dutcher

发明人： Hieu V. Le ,  John Edward Morris ,  Cindy M. Setum ,  Robert G. Dutcher

IPC分类号： A61M2500

CPC分类号： A61M25/0054 ,  A61M25/005 ,  A61M25/0053 ,  A61M2025/0042

摘要： Flexible microcatheter having regions of different flexibility integrally and strategically placed along and about the length of a one-piece composite catheter tube. Distally the flexible microcatheter exhibits pronounced flexibility with respect to locations or regions of flexibility located proximally for navigation along tortuous vascular paths. Different regions of flexibility are formed by applying resins of different Shore hardness readings either singularly or in combination along and about a braid which overlies an inner resin layer. The encapsulated braid provides resistance to kinking and bending of the flexible microcatheter as well as providing for torque transmission and pushability along the length of the flexible microcatheter.

摘要翻译： 柔性微导管具有不同柔性的区域，整体地并且沿着并且围绕一体式复合导管的长度有策略地放置。 远端地，柔性微导管相对于靠近曲折的血管路径导航的近端位置或柔性区域具有显着的灵活性。 不同的柔性区域通过单独或组合地施加不同邵氏硬度读数的树脂形成，并且围绕着位于内层树脂层上的编织物。 封装的编织物提供柔性微导管的扭结和弯曲的抗性，以及沿着柔性微导管的长度提供扭矩传递和推压性。