专利检索 ap:("Nicola Mongelli" OR "Giovanni Biasoli" OR "Maria Grandi" OR "Marina Ciomei" OR "Maria C. Geroni") AND inv:"Giovanni Biasoli" 第 2 页

11.

发明授权
Isoindoline derivatives for treating pain 失效
标题翻译：用于治疗疼痛的异二氢吲哚衍生物

公开(公告)号：US4118504A

公开(公告)日：1978-10-03

申请号：US763522

申请日：1977-01-28

申请人： PierNicola Giraldi , Giuliano Nannini , Willy Logemann , Raffaele Tommasini , Ada Buttinoni , Giovanni Biasoli

发明人： PierNicola Giraldi , Giuliano Nannini , Willy Logemann , Raffaele Tommasini , Ada Buttinoni , Giovanni Biasoli

IPC分类号： C07D209/44 , C07D209/46 , C07D209/48 , A61K31/40

CPC分类号： C07D209/48 , C07D209/44 , C07D209/46

摘要： Isoindoline derivatives are disclosed, as for instance of the formula: ##STR1## and methods of preparation of these compounds, such as the reaction of o-cyano-benzylbromide with a compound of formula ##STR2## and subsequent saponification. The compounds possess analgesic and anti-inflammatory activity.

摘要翻译： 公开了异吲哚啉衍生物，例如下式：＆lt; IMAGE＆gt;和这些化合物的制备方法，例如邻氰基 - 苄基溴与式“IMAGE”化合物的反应和随后的皂化。

12.

发明授权
Acryloyl substituted distamycin derivatives, process for preparing them, and their use as antitumor and antiviral agents 有权
标题翻译：丙烯酰取代的雷霉霉素衍生物，其制备方法及其作为抗肿瘤剂和抗病毒剂的用途

公开(公告)号：US06482920B1

公开(公告)日：2002-11-19

申请号：US09147573

申请日：1999-01-22

申请人： Paolo Cozzi , Italo Beria , Giovanni Biasoli , Marina Caldarelli , Laura Capolongo , Cristina Franzetti

发明人： Paolo Cozzi , Italo Beria , Giovanni Biasoli , Marina Caldarelli , Laura Capolongo , Cristina Franzetti

IPC分类号： C07K508

CPC分类号： C07D207/34

摘要： The present invention relates to acrylol substituted distamycin derivatives, to pharmaceutical compositions comprising such derivatives as well as their use in methods of treating humans and animals, particularly as anti-tumor agents.

摘要翻译： 本发明涉及丙烯酰取代的雷霉霉素衍生物，包含这些衍生物的药物组合物以及它们在治疗人和动物，特别是作为抗肿瘤剂的方法中的用途。