专利检索 ap:("Paolo Carminati" OR "Giovanni Salvatori" OR "Romani Luigina") AND inv:"Giovanni Salvatori" 第 2 页

11.

发明授权
Esters of L-carnitine of alkanoyl L-carnitines useful as cationic lipids for the intracellular delivery of pharmacologically active compounds 失效
标题翻译：用作阳离子脂质的烷酰基L-肉碱的左旋肉碱的酯用于细胞内递送药理学活性化合物

公开(公告)号：US07629003B2

公开(公告)日：2009-12-08

申请号：US10624645

申请日：2003-07-23

申请人： Claudio Pisano , Maria Ornella Tinti , Mosé Santaniello , Luciana Critelli , Giovanni Salvatori

发明人： Claudio Pisano , Maria Ornella Tinti , Mosé Santaniello , Luciana Critelli , Giovanni Salvatori

IPC分类号： A61K9/127

CPC分类号： C07C229/22 , A61K8/14 , A61K8/44 , A61K9/0019 , A61K9/127 , A61K9/1272 , A61K9/1277 , A61K9/19 , A61K31/225 , A61K48/00 , A61Q19/00

摘要： Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine and alkanoyl L-carnitines of formula (I) are also disclosed wherein the R groups are as defined in the description.

摘要翻译： 描述了左旋肉碱和烷酰基L-肉碱的酯，其可用作阳离子脂质用于药理学活性化合物的细胞内递送。还公开了式（I）的L-肉碱和烷酰基L-肉毒碱的新酯，其中R基团如说明书中所定义。