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公开(公告)号：US09114144B2
公开(公告)日：2015-08-25
申请号：US13228300
申请日：2011-09-08
申请人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
发明人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US20120015881A1
公开(公告)日：2012-01-19
申请号：US13228300
申请日：2011-09-08
申请人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
发明人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US20080226655A1
公开(公告)日：2008-09-18
申请号：US11929685
申请日：2007-10-30
申请人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
发明人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
IPC分类号： A61K39/395
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US07153829B2
公开(公告)日：2006-12-26
申请号：US10953902
申请日：2004-09-27
申请人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
发明人： Robert C. Ladner , Arthur C. Ley , Shirish Hirani , Anthony Williams , Maria Grazia De Simoni , Luigi Bergamaschini
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
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公开(公告)号：US20080152656A1
公开(公告)日：2008-06-26
申请号：US11931635
申请日：2007-10-31
IPC分类号： A61K39/395 , A61P43/00
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US07064107B2
公开(公告)日：2006-06-20
申请号：US10456986
申请日：2003-06-06
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g., coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中的缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应，例如冠状动脉旁路移植术和其他外科手术，特别是当这样 手术涉及体外循环，如体外循环。
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公开(公告)号：US08710007B2
公开(公告)日：2014-04-29
申请号：US12951543
申请日：2010-11-22
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US08124586B2
公开(公告)日：2012-02-28
申请号：US11929729
申请日：2007-10-30
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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公开(公告)号：US08034775B2
公开(公告)日：2011-10-11
申请号：US11929822
申请日：2007-10-30
CPC分类号： A61K38/57
摘要： Methods are described for preventing or reducing ischemia, e.g., cerebral ischemia, and/or reperfusion injury, e.g., reperfusion injury associated with cerebral ischemia, in a patient.
摘要翻译： 描述了用于预防或减少患者中局部缺血，例如脑缺血和/或再灌注损伤（例如与脑缺血相关的再灌注损伤）的方法。
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公开(公告)号：US20110086801A1
公开(公告)日：2011-04-14
申请号：US12951543
申请日：2010-11-22
CPC分类号： A61K38/57 , A61K9/0019 , A61K38/55 , C12N9/6445
摘要： Methods are described for preventing or reducing ischemia and/or systemic inflammatory response in a patient such as perioperative blood loss and/or systemic inflammatory response in a patient subjected to cardiothoracic surgery, e.g. coronary artery bypass grafting and other surgical procedures, especially when such procedures involve extra-corporeal circulation, such as cardiopulmonary bypass.
摘要翻译： 描述了用于预防或减少患者中缺血和/或全身炎症反应的方法，例如进行心胸外科手术的患者中的围手术期失血和/或全身炎症反应。 冠状动脉旁路移植术等外科手术，特别是当此类手术涉及体外循环，如体外循环时。
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