公开(公告)号：US20180340830A1

公开(公告)日：2018-11-29

申请号：US15989983

申请日：2018-05-25

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Daejong YANG ,  Hyunjun CHO ,  Youngzoon YOON ,  Hyuck CHOO

IPC: G01J3/44 ,  C23C18/08 ,  C23C18/06 ,  G01N21/65

Abstract: A substrate for sensing, a method of manufacturing the substrate, and an analyzing apparatus including the substrate are provided. The substrate for sensing includes: a support layer; a plurality of metal nanoparticle clusters arranged on the support layer; and a plurality of perforations arranged among the plurality of metal nanoparticle clusters. The plurality of metal nanoparticle clusters each comprise a plurality of metal nanoparticles stacked in a three-dimensional structure. Each of the plurality of perforations transmits incident light therethrough.

公开(公告)号：US20180335387A1

公开(公告)日：2018-11-22

申请号：US15986246

申请日：2018-05-22

Applicant: SAMSUNG ELECTRONICS CO., LTD. ,  CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Jeongoen LEE ,  Daejong YANG ,  Youngzoon YOON ,  Hyuck CHOO

IPC: G01N21/65

Abstract: An apparatus and method for quantitatively sensing and analyzing a concentration of biomolecules using Raman peak shift are disclosed. The quantitative molecular sensing apparatus includes an illumination optical system including a light source configured to irradiate excitation light onto an object, a detection optical system including an optical detector configured to detect light scattered from the object, and a signal processor configured to analyze properties of the object based on signal output by the detection optical system and to calculate a concentration of target molecules in the object based on a Raman peak shift value over a predetermined time period.