公开(公告)号：US20060251666A1

公开(公告)日：2006-11-09

申请号：US10525831

申请日：2003-08-29

申请人： Tetsuya Nakatsura ,  Yasuharu Nishimura

发明人： Tetsuya Nakatsura ,  Yasuharu Nishimura

IPC分类号： A61K39/00 ,  C12Q1/68 ,  G01N33/574 ,  C07H21/04 ,  C12P21/06 ,  C12N5/08 ,  C07K14/82

CPC分类号： G01N33/57419 ,  A61K39/00 ,  C07K14/4748 ,  G01N33/57438

摘要： An object of the present invention to provide: a human pancreatic cancer antigen and/or a human colon cancer antigen that can be applied to the diagnosis and/or treatment of various types of cancers or tumors including pancreatic cancer and colon cancer as representative examples; a gene encoding the same; an anti-cancer vaccine using the same; or the like. The present invention provides a cancer antigen comprising a protein having the amino acid sequence shown in SEQ ID NO: 1; a peptide comprising a portion of said protein and having immune-stimulating activity; an anti-cancer vaccine comprising said peptide; a DNA having the nucleotide sequence shown in SEQ ID NO: 2, or its complementary sequence or a part or full length of these sequence; an anti-cancer vaccine comprising said DNA; and use thereof.

摘要翻译： 本发明的目的是提供：可用于诊断和/或治疗包括胰腺癌和结肠癌的各种类型的癌症或肿瘤的人胰腺癌抗原和/或人结肠癌抗原作为代表性实例; 编码该基因的基因; 使用其的抗癌疫苗; 或类似物。 本发明提供包含具有SEQ ID NO：1所示氨基酸序列的蛋白质的癌抗原; 包含所述蛋白质的一部分并具有免疫刺激活性的肽; 包含所述肽的抗癌疫苗; 具有SEQ ID NO：2所示核苷酸序列的DNA或其互补序列或这些序列的部分或全长; 包含所述DNA的抗癌疫苗; 及其用途。