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11.
公开(公告)号:US20100087502A1
公开(公告)日:2010-04-08
申请号:US12529561
申请日:2008-03-05
申请人: Christopher Norbert Johnson , David G. Jones , Xi Liang , David Timothy Macpherson , Aaron B. Miller , Antoinette Naylor , Steven James Stanway , Andrew Kenneth Takle , Giancarlo Trani
发明人: Christopher Norbert Johnson , David G. Jones , Xi Liang , David Timothy Macpherson , Aaron B. Miller , Antoinette Naylor , Steven James Stanway , Andrew Kenneth Takle , Giancarlo Trani
IPC分类号: A61K31/416 , C07D231/56 , A61P9/00 , A61P25/00 , A61P29/00 , A61P37/00 , A61P3/00
CPC分类号: C07D231/56
摘要: The present invention relates to novel indazole derivatives having pharmacological activity, processes for their preparation, compositions containing them and uses of these compounds in the treatment of estrogen receptor beta mediated diseases.
摘要翻译: 本发明涉及具有药理学活性的新的吲唑衍生物,其制备方法,含有它们的组合物以及这些化合物在治疗雌激素受体β介导的疾病中的用途。
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公开(公告)号:US4492461A
公开(公告)日:1985-01-08
申请号:US357553
申请日:1982-03-12
申请人: David G. Jones , Oh K. Kwon
发明人: David G. Jones , Oh K. Kwon
CPC分类号: G01N15/0612
摘要: An improved method of producing a deposit of particles from a liquid medium carrier on a substrate for subsequent optical analysis of the particles, involves feeding the liquid medium carrying the particles to the substrate via a flexible tube which is not subjected to fluctuating lateral compressions. The invention has particular relevance to the making of Ferrograms from wear debris in a sample of machine lubricant.
摘要翻译: 一种从基材上的液体介质载体产生颗粒沉积物的改进方法,用于随后的颗粒的光学分析,包括通过未经受波动的侧向压缩的柔性管将携带颗粒的液体介质送入基板。 本发明与在机器润滑剂样品中的磨损碎屑的制造特别相关。
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公开(公告)号:USRE30987E
公开(公告)日:1982-06-29
申请号:US146387
申请日:1980-05-05
申请人: David G. Jones
发明人: David G. Jones
摘要: A clock has a clock face in the form of an axially symmetric solid, e.g. a sphere, a cone or a cylinder. Clock hands extend around the clock face following a helical path, and time-indicating markings are arranged on all the surfaces of the face. It is therefore possible for a complete set of these markings to be seen from any direction relative to the clock face. The hands are normally driven by a conventional clock movement, there being an hour hand and a minute hand. However, it would be possible in some applications to have only a single hand, e.g. a minute hand, and to drive the clock face relative to the hand. The markings are arranged along helical paths, corresponding to the helical shape of the hands.
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公开(公告)号:US20100324106A1
公开(公告)日:2010-12-23
申请号:US12864933
申请日:2009-02-17
申请人: Christopher Norbert Johnson , David G. Jones , Xi Liang , David Timothy Macpherson , Aaron B. Miller , Steven James Stanway , Andrew Kenneth Takle , Giancarlo Trani , Antoinette Wilson
发明人: Christopher Norbert Johnson , David G. Jones , Xi Liang , David Timothy Macpherson , Aaron B. Miller , Steven James Stanway , Andrew Kenneth Takle , Giancarlo Trani , Antoinette Wilson
IPC分类号: A61K31/404 , C07D209/12 , A61P9/00 , A61P29/00 , A61P35/00 , A61P25/00 , A61P3/00 , A61P3/04
CPC分类号: C07D209/08
摘要: The present invention relates to novel indole derivatives having pharmacological activity, processes for their preparation, compositions containing them and the use of these compounds in the treatment of estrogen receptor beta mediated diseases.
摘要翻译: 本发明涉及具有药理活性的新型吲哚衍生物,其制备方法,含有它们的组合物以及这些化合物在治疗雌激素受体β介导的疾病中的用途。
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公开(公告)号:US07956083B2
公开(公告)日:2011-06-07
申请号:US12864933
申请日:2009-02-17
申请人: Christopher Norbert Johnson , David G. Jones , Xi Liang , David Timothy MacPherson , Aaron B Miller , Steven James Stanway , Andrew Kenneth Takle , Giancarlo Trani , Antoinette Wilson
发明人: Christopher Norbert Johnson , David G. Jones , Xi Liang , David Timothy MacPherson , Aaron B Miller , Steven James Stanway , Andrew Kenneth Takle , Giancarlo Trani , Antoinette Wilson
IPC分类号: A01N43/38 , C07D209/04
CPC分类号: C07D209/08
摘要: The present invention relates to novel indole derivatives having pharmacological activity, processes for their preparation, compositions containing them and the use of these compounds in the treatment of estrogen receptor beta mediated diseases.
摘要翻译: 本发明涉及具有药理活性的新型吲哚衍生物,其制备方法,含有它们的组合物以及这些化合物在治疗雌激素受体β介导的疾病中的用途。
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公开(公告)号:US4144708A
公开(公告)日:1979-03-20
申请号:US761610
申请日:1977-01-24
申请人: David G. Jones
发明人: David G. Jones
CPC分类号: G04B19/04
摘要: A clock has a clock face in the form of an axially symmetric solid, e.g. a sphere, a cone or a cylinder. Clock hands extend around the clock face following a helical path, and time-indicating markings are arranged on all the surfaces of the face. It is therefore possible for a complete set of these markings to be seen from any direction relative to the clock face. The hands are normally driven by a conventional clock movement, there being an hour hand and a minute hand. However, it would be possible in some applications to have only a single hand, e.g. a minute hand, and to drive the clock face relative to the hand. The markings are arranged along helical paths, corresponding to the helical shape of the hands.
摘要翻译: 时钟具有轴对称固体形式的钟表面,例如。 球体,圆锥体或圆柱体。 时钟指针沿着螺旋路径延伸到时钟表面,时间指示标记布置在脸部的所有表面上。 因此,可以从相对于时钟面的任何方向看到一整套这些标记。 手通常由传统的时钟运动驱动,有一个时针和一只手。 然而,在一些应用中可能只有单手,例如, 一分钟的手,并相对于手驱动钟面。 标记沿着螺旋形路径布置,对应于手的螺旋形状。
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