公开(公告)号：US20230083661A1

公开(公告)日：2023-03-16

申请号：US17990454

申请日：2022-11-18

Applicant: University of Kansas ,  The Regents of the University of Michigan

Inventor： Xinmai Yang ,  Xueding Wang ,  Yannis M. Paulus

IPC: A61N7/02 ,  A61F9/008 ,  A61B5/107

Abstract: A method of removing microvessels includes applying a burst of acoustic energy at a target location, applying a pulse of optical energy at the target location, and promoting cavitation at the target location by synchronizing an arrival of the burst of acoustic energy and the optical energy at the target location. The burst of acoustic energy has a pressure below 5.0 MPa. The pulse of optical energy at the target location has a fluence less than 100 mJ/cm2. At least a portion of the pulse is concurrent with the burst and the optical energy has an optical area that is overlapping with an acoustic area of the acoustic energy at the target location.