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11.发明申请Implantable Drug Delivery Devices Having Alternating Hyrdrophilic And Amphiphilic Polymer Layers 有权具有交替的亲和性和两亲性聚合物层的可植入药物递送装置公开(公告)号：US20090297575A1
公开(公告)日：2009-12-03
申请号：US12130162
申请日：2008-05-30
IPC分类号： A61F2/00
CPC分类号： A61L31/10 , A61L31/148 , A61L2420/08 , Y10T428/31551 , Y10T428/31562 , Y10T428/31591 , Y10T428/31736 , Y10T428/3175 , Y10T428/31786 , Y10T428/3179 , Y10T428/31855 , Y10T428/31891
摘要： An implantable drug delivery medical device with alternating hydrophilic and amphiphilic polymer layers and methods of using for the treatment of vascular disease are disclosed.
摘要翻译： 公开了具有交替的亲水和两亲性聚合物层的可植入药物递送医疗装置和用于治疗血管疾病的方法。
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12.发明授权Poly(amide) and poly(ester-amide) polymers and drug delivery particles and coatings containing same 有权聚（酰胺）和聚（酯 - 酰胺）聚合物和药物递送颗粒和含有它们的涂层公开(公告)号：US08916187B2
公开(公告)日：2014-12-23
申请号：US13221767
申请日：2011-08-30
CPC分类号： C08L77/12 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/62 , C08G69/44 , C08G69/48
摘要： The current invention relates to poly(amide) and poly(ester-amide) polymers, coatings including the polymers, and narrow polydispersity drug delivery particles including the polymers.
摘要翻译： 本发明涉及聚（酰胺）和聚（酯 - 酰胺）聚合物，包括聚合物的涂层和包括聚合物的窄多分散药物递送颗粒。
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公开(公告)号：US08333984B2
公开(公告)日：2012-12-18
申请号：US13206417
申请日：2011-08-09
IPC分类号： A61F2/00
CPC分类号： A61K47/32 , A61F2/82 , A61K45/06 , A61K47/65 , A61K47/6957 , A61L31/10 , A61L31/16 , A61L2300/00 , C08L33/26
摘要： An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.
摘要翻译： 提供了包括由丙烯酰胺类共聚物和生物活性剂形成的共轭物的可植入装置。
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14.发明申请Implantable Medical Device With Poly(Vinylidene Fluoride-Co-Hexafluoropropylene)/Zotarolimus Drug Layer 审中-公开具有聚（亚乙烯基氟化物 - 共 - 六氟丙烯）/佐他莫司药物层的可植入医疗器械公开(公告)号：US20110229548A1
公开(公告)日：2011-09-22
申请号：US12727175
申请日：2010-03-18
IPC分类号： A61F2/82 , A61K31/436 , A61F2/06
CPC分类号： A61L31/16 , A61L31/10 , A61L2300/416 , A61L2420/08 , C08L27/20 , C08L27/16
摘要： This invention relates to an implantable medical device for and method of treating a vascular disease where the device is preferably a stent comprising a drug reservoir layer comprising poly(vinylidene fluoride-co-hexafluoropropylene) and zotarolimus.
摘要翻译： 本发明涉及一种用于治疗血管疾病的可植入医疗装置及其方法，其中装置优选为支架，其包括含有聚（偏二氟乙烯 - 共 - 六氟丙烯）和佐他莫司的药物储存层。
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公开(公告)号：US08486135B2
公开(公告)日：2013-07-16
申请号：US11784886
申请日：2007-04-09
申请人： Yunbing Wang , David C. Gale , Bin Huang , Mikael O. Trollsas , Thierry Glauser , Florian Ludwig
发明人： Yunbing Wang , David C. Gale , Bin Huang , Mikael O. Trollsas , Thierry Glauser , Florian Ludwig
IPC分类号： A61F2/06
摘要： This invention relates to implantable medical devices, such as stents, fabricated from hyperbranched-like polymers, comb-like polymers, star polymers, dendrimer-like star polymers, dendrimers, and mixtures thereof.
摘要翻译： 本发明涉及由超支化聚合物，梳状聚合物，星形聚合物，树枝状大分子星形聚合物，树枝状大分子及其混合物制成的可植入医疗装置，例如支架。
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16.发明申请POLY(AMIDE) AND POLY(ESTER-AMIDE) POLYMERS AND DRUG DELIVERY PARTICLES AND COATINGS CONTAINING SAME 有权聚（酰胺）和聚（酰胺）聚合物和药物递送颗粒和包含它们的涂料公开(公告)号：US20110311596A1
公开(公告)日：2011-12-22
申请号：US13221767
申请日：2011-08-30
IPC分类号： A61K9/14 , A61K47/34 , A61K31/436 , A61K31/675 , B82Y5/00
CPC分类号： C08L77/12 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/62 , C08G69/44 , C08G69/48
摘要： The current invention relates to poly(amide) and poly(ester-amide) polymers, coatings including the polymers, and narrow polydispersity drug delivery particles including the polymers.
摘要翻译： 本发明涉及聚（酰胺）和聚（酯 - 酰胺）聚合物，包括聚合物的涂层和包括聚合物的窄多分散药物递送颗粒。
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17.发明申请Poly(Amide) And Poly(Ester-Amide) Polymers And Drug Delivery Particles And Coatings Containing Same 有权聚（酰胺）和聚（酯 - 酰胺）聚合物和药物递送颗粒和包含它们的涂料公开(公告)号：US20090324671A1
公开(公告)日：2009-12-31
申请号：US12165173
申请日：2008-06-30
CPC分类号： C08L77/12 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/62 , C08G69/44 , C08G69/48
摘要： The current invention relates to poly(amide) and poly(ester-amide) polymers, coatings including the polymers, and narrow polydispersity drug delivery particles including the polymers.
摘要翻译： 本发明涉及聚（酰胺）和聚（酯 - 酰胺）聚合物，包括聚合物的涂层和包括聚合物的窄多分散药物递送颗粒。
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公开(公告)号：US20080200377A1
公开(公告)日：2008-08-21
申请号：US11676175
申请日：2007-02-16
申请人： Mikael O. Trollsas , Thierry Glauser , Michael Ngo , Jinping Wan
发明人： Mikael O. Trollsas , Thierry Glauser , Michael Ngo , Jinping Wan
CPC分类号： A61K9/0019 , A61K9/5031 , A61K47/34
摘要： A composition including a solution suitable for introduction into a blood vessel comprising particles comprising a treatment agent and a polymeric product of at least one activated diamine and at least one activated dicarboxylic acid. A method including introducing a delivery device into a blood vessel; and introducing a solution into the blood vessel, the solution comprising particles comprising a treatment agent and a polymeric product of at least one activated diamine and at least one activated dicarboxylic acid, wherein the activated diamine comprises a product of a diol and an amino acid. A method including combining a treatment agent and a polymeric product of at least one activated diamine and at least one activated dicarboxylic acid; and forming particles of the combination suitable for delivery through a blood vessel.
摘要翻译： 一种包含适于引入血管的溶液的组合物，其包含包含至少一种活化二胺和至少一种活化二羧酸的处理剂和聚合物的颗粒。 一种包括将输送装置引入血管的方法; 并将溶液引入血管中，所述溶液包含包含至少一种活化二胺和至少一种活化二羧酸的处理剂和聚合物的颗粒，其中所述活化二胺包括二醇和氨基酸的产物。 一种方法，包括将处理剂和至少一种活化二胺和至少一种活化的二羧酸的聚合物组合; 以及形成适于通过血管输送的组合颗粒。
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19.发明授权公开(公告)号：US08765162B2
公开(公告)日：2014-07-01
申请号：US12165173
申请日：2008-06-30
IPC分类号： A61F2/02
CPC分类号： C08L77/12 , A61L31/10 , A61L31/16 , A61L2300/416 , A61L2300/602 , A61L2300/606 , A61L2300/62 , C08G69/44 , C08G69/48
摘要： The current invention relates to poly(amide) and poly(ester-amide) polymers, coatings including the polymers, and narrow polydispersity drug delivery particles including the polymers.
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公开(公告)号：US08017141B2
公开(公告)日：2011-09-13
申请号：US11639860
申请日：2006-12-15
IPC分类号： A61F2/00
CPC分类号： A61K47/32 , A61F2/82 , A61K45/06 , A61K47/65 , A61K47/6957 , A61L31/10 , A61L31/16 , A61L2300/00 , C08L33/26
摘要： An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.
摘要翻译： 提供了包括由丙烯酰胺类共聚物和生物活性剂形成的共轭物的可植入装置。
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