摘要:
Disclosed are compounds of the formula wherein Z1 is —CH2— or —C(O)—, R4 and R5 are carbon chains (and optionally, together can form a C2 bridge), u and v are independently an integer of 0-3 such that there sum is from 3 to 5, and R2 is heteroaryl, and R1 and R3 are as defined herein. Also disclosed are methods of treating pain using a compound of formula I.
摘要翻译:公开了下式的化合物其中Z 1是-CH 2 - 或-C(O) - ,R 4和R 4, 5是碳链(并且可选地,一起可以形成C 2 H 2桥),u和v独立地是0-3的整数,使得总和为3至5,并且 R 2是杂芳基,R 1和R 3如本文所定义。 还公开了使用式I化合物治疗疼痛的方法。