公开(公告)号：US09040694B1

公开(公告)日：2015-05-26

申请号：US14337412

申请日：2014-07-22

Applicant: Vanderbilt University

Inventor： Charles C. Hong ,  Corey R. Hopkins ,  Antonis K. Hatzopoulos ,  Craig W. Lindsley ,  Jijun Hao

IPC: A61K31/5377 ,  C07D413/14 ,  C12N5/0735 ,  G01N33/50 ,  C07D487/04

CPC classification number: C12N5/0606 ,  A61K31/5377 ,  C07D413/14 ,  C07D487/04 ,  C12N2501/40 ,  G01N33/5026

Abstract: The presently-disclosed subject matter relates to compounds of the formula: and methods for use thereof. The presently-disclosed subject matter relates methods of selectively differentiating a stem cell, and methods of screening for compounds useful for enhancing terminal differentiation of committed cardiac progenitor cells.

Abstract translation: 目前公开的主题涉及下式的化合物及其使用方法。 目前公开的主题涉及选择性区分干细胞的方法和筛选用于增强确定的心脏祖细胞的末端分化的化合物的方法。