专利检索 ap:("Vanderbilt University" OR "The Trustees of the University of Pennsylvania") AND inv:"Adegoke O. Adeniji" 第 2 页

11.

发明授权
Bifunctional AKR1C3 inhibitors/androgen receptor modulators and methods of use thereof 有权

公开(公告)号：US10071953B2

公开(公告)日：2018-09-11

申请号：US14993742

申请日：2016-01-12

申请人： The Trustees of the University of Pennsylvania

发明人： Trevor M. Penning , Adegoke O. Adeniji , Michael C. Byrns , Jeffrey Winkler , Barry Twenter

IPC分类号： C07C229/60 , A61K31/196 , A61P35/00 , C07C229/58 , A61K31/195 , A61K31/205 , A61K45/06 , A61K31/405

CPC分类号： C07C229/58 , A61K31/195 , A61K31/196 , A61K31/205 , A61K31/405 , A61K45/06 , C07C229/60 , A61K2300/00

摘要： The invention includes compositions comprising selective AKR1C3 inhibitors. The invention also includes compositions comprising bifunctional AKR1C3 inhibitors and selective androgen receptor modulators. The invention further includes methods of treatment using the compositions of the invention.

12.

发明申请
Bifunctional AKR1C3 Inhibitors/Androgen Receptor Modulators and Methods of Use Thereof 有权
标题翻译：双功能AKR1C3抑制剂/雄激素受体调节剂及其使用方法

公开(公告)号：US20140107085A1

公开(公告)日：2014-04-17

申请号：US14050937

申请日：2013-10-10

申请人： The Trustees of The University of Pennsylvania

发明人： Trevor M. Penning , Adegoke O. Adeniji , Michael C. Burns , Jeffrey Winkler , Barry Twenter

IPC分类号： C07C229/60 , A61K31/196 , A61K45/06 , A61K31/405

CPC分类号： C07C229/58 , A61K31/195 , A61K31/196 , A61K31/205 , A61K31/405 , A61K45/06 , C07C229/60 , A61K2300/00

摘要： The invention includes compositions comprising selective AKR1C3 inhibitors. The invention also includes compositions comprising bifunctional AKR1C3 inhibitors and selective androgen receptor modulators. The invention further includes methods of treatment using the compositions of the invention.

摘要翻译： 本发明包括包含选择性AKR1C3抑制剂的组合物。本发明还包括包含双功能AKR1C3抑制剂和选择性雄激素受体调节剂的组合物。本发明还包括使用本发明组合物的治疗方法。