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16 条记录 (耗时 0.025 秒)

    DERMAL REGENERATION ENHANCER
    12.
    发明申请
    DERMAL REGENERATION ENHANCER 审中-公开
    永久再生增强剂

    公开(公告)号：US20090017123A1

    公开(公告)日：2009-01-15

    申请号：US11912959

    申请日：2006-04-28

    申请人： Yoko Yamaguchi ,  Rie Igarashi

    发明人： Yoko Yamaguchi ,  Rie Igarashi

    IPC分类号： A61K9/14 ,  A61K31/07 ,  A61K31/11 ,  A61K31/70 ,  A61K38/44

    CPC分类号： A61K8/0295 ,  A61K8/86 ,  A61Q19/02 ,  A61Q19/08

    摘要： An object of the present invention is to provide a novel dermal regeneration enhancer. In accordance with the present invention, there is provided a dermal regeneration enhancer as a novel pharmaceutical use of lyotropic liquid crystal which has been utilized as a basic material for pharmaceutical preparations for external application and for cosmetics, and the dermal regeneration enhancer of the present invention achieves an excellent suppressive effect to aging of the skin, generation of spots, etc.

    摘要翻译： 本发明的目的是提供一种新颖的皮肤再生增强剂。 根据本发明，提供了作为用作外用药用制剂和化妆品的基础材料的溶致液晶的新药用途的真皮再生增强剂，本发明的皮肤再生增强剂 对皮肤老化，斑点产生等产生极好的抑制作用

    THERAPEUTIC AGENT FOR LOCAL INFLAMMATION
    13.
    发明申请
    THERAPEUTIC AGENT FOR LOCAL INFLAMMATION 审中-公开
    局部炎症治疗剂

    公开(公告)号：US20110081410A1

    公开(公告)日：2011-04-07

    申请号：US11993209

    申请日：2006-06-23

    申请人： Rie Igarashi

    发明人： Rie Igarashi

    IPC分类号： A61K9/48 ,  A61K31/203 ,  A61K31/07 ,  A61P29/00 ,  A61P19/02

    CPC分类号： A61K9/0014 ,  A61K9/5115 ,  A61K31/07 ,  A61K31/203

    摘要： The agents of the present invention comprise, as a main ingredient, a polyvalent metal inorganic-salt nanocapsule which encapsulates a retinoid such as retinoic acid. The agents could penetrate into a joint when applied to the skin and induce hyaluronic acid production in a synovial membrane or chondrocyte. Moreover, application of the nanocapsule of the present invention to the skin for a certain period of time lowered the values of inflammatory cytokines and MMPs in the blood.

    摘要翻译： 作为主要成分，本发明的药剂含有视黄酸等视黄酸类的多价金属无机盐纳米胶囊。 当施用于皮肤并且在滑膜或软骨细胞中诱导透明质酸产生时，所述药剂可以渗透到关节中。 此外，本发明的纳米胶囊在皮肤上施用一定时间降低了血液中炎性细胞因子和MMP的值。

    TRANSDERMAL ABSORPTION ENHANCER
    14.
    发明申请
    TRANSDERMAL ABSORPTION ENHANCER 审中-公开
    超吸收增强剂

    公开(公告)号：US20090075860A1

    公开(公告)日：2009-03-19

    申请号：US11912964

    申请日：2006-04-28

    申请人： Yoko Yamaguchi ,  Rie Igarashi

    发明人： Yoko Yamaguchi ,  Rie Igarashi

    IPC分类号： A61K38/02 ,  A61K47/44 ,  A61K47/34 ,  A61K47/06 ,  A61K31/711

    CPC分类号： A61K31/23 ,  A61K9/0014 ,  A61K9/06 ,  A61K9/1274 ,  A61K31/203 ,  A61K47/12 ,  A61K47/44

    摘要： An object of the present invention is to provide a transdermal absorption enhancer by which various active ingredients are transdermally absorbed. In accordance with a transdermal absorption enhancer of the present invention which effective ingredient is lyotropic liquid crystal which has been utilized as a basic material for pharmaceutical preparations for external application and for cosmetics, transdermal absorption of a macromolecular substance and a water-soluble substance was able to be improved.

    摘要翻译： 本发明的目的是提供一种经皮吸收增强剂，通过其可以透皮吸收各种活性成分。 根据本发明的透皮吸收增强剂，其有效成分是已经用作外用药物制剂和化妆品的基础材料的溶致液晶，能够对大分子物质和水溶性物质进行经皮吸收 要改进

    Retinoic Acid-Containing Antidiabetic Agent
    15.
    发明申请
    Retinoic Acid-Containing Antidiabetic Agent 审中-公开
    含视黄酸的抗糖尿病药

    公开(公告)号：US20080274193A1

    公开(公告)日：2008-11-06

    申请号：US10586775

    申请日：2005-01-21

    申请人： Yoko Yamaguchi ,  Rie Igarashi

    发明人： Yoko Yamaguchi ,  Rie Igarashi

    IPC分类号： A61K31/203 ,  C07C57/03 ,  A61K9/14 ,  A61P3/10

    CPC分类号： A61K31/203

    摘要： The present invention aims to provide a novel agent for treating and/or preventing diabetes which agent can not only control a blood sugar level but also fundamentally treat a patient with type I diabetes suffering from destruction of β cells and a patient with type II diabetes suffering from dysfunction in insulin secretion. The present invention provides an agent for treating and/or preventing diabetes, the agent containing retinoic acid as an active ingredient. Retinoic acid incorporated as an active ingredient may be all-trans retinoic acid, an isomer thereof, a derivative thereof, a salt thereof or a prodrug thereof. Retinoic acid may be incorporated singly. Alternatively, composite particles of retinoic acid and an appropriate inorganic or organic substance are prepared, and the retinoic acid composite particles may be incorporated.

    摘要翻译： 本发明的目的在于提供一种用于治疗和/或预防糖尿病的新型药剂，其不仅可以控制血糖水平，而且可以从根本上治疗患有β细胞破坏的I型糖尿病患者和患有II型糖尿病的患者 从胰岛素分泌功能障碍。 本发明提供了用于治疗和/或预防糖尿病的药剂，其含有视黄酸作为活性成分。 作为活性成分掺入的视黄酸可以是全反式视黄酸，其异构体，其衍生物，其盐或其前药。 维甲酸可以单独加入。 或者，制备视黄酸和合适的无机或有机物质的复合颗粒，并且可以加入视黄酸复合颗粒。