专利检索 caee:"ENTERPRISE THERAPEUTICS LIMITED" 第 2 页

11.

发明申请
BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS 有权

公开(公告)号：US20210147432A1

公开(公告)日：2021-05-20

申请号：US17103559

申请日：2020-11-24

申请人： ENTERPRISE THERAPEUTICS LIMITED

发明人： Clive McCARTHY , Jonathan David HARGRAVE , Duncan Alexander HAY , Thomas Beauregard SCHOFIELD , Naomi WENT

IPC分类号： C07D487/04 , A61P11/12 , A61K9/00

摘要： Compounds of general formula (I) wherein R1, R2, R3, R4, R5 and X are as defined herein are inhibitors of the epithelial sodium channel (ENaC) and are useful for the treatment or prevention respiratory diseases and conditions, skin conditions and ocular conditions.